LOCUS X07698 1111 bp mRNA linear ROD 03-APR-1995
DEFINITION Mouse mRNA for CD8 molecule Ly-3 chain.
ACCESSION X07698
VERSION X07698.1
KEYWORDS CD8 antigen; cell surface antigen; glycoprotein; immunoglobulin
superfamily; Ly-3 protein; T-cell surface glycoprotein.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 1111)
AUTHORS Blanc D., Bron C., Gabert J., Letourneur F., MacDonald H.R.,
Malissen B.
TITLE Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular
complex: co-transfer with the Ly-2 polypeptide gene results in
detectable cell surface expression of the Ly-3 antigenic
determinants
JOURNAL Eur. J. Immunol. 18(4), 613-619(1988).
PUBMED 2452747
COMMENT The region from amino acid 22 to 136 shows clear homology to Ig and
T cell receptor variable (V) regions.
Data kindly reviewed (06-Mar-1989) by Malissen B.
FEATURES Location/Qualifiers
source 1..1111
/organism="Mus musculus"
/mol_type="mRNA"
/clone_lib="KB5-C20 CTL"
/clone="pLy-3-23.1"
/db_xref="taxon:10090"
CDS 50..691
/note="Ly-3 precursor protein"
/db_xref="GOA:P10300"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013106"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036179"
/db_xref="InterPro:IPR042414"
/db_xref="MGI:MGI:88347"
/db_xref="PDB:2ATP"
/db_xref="PDB:3B9K"
/db_xref="PDB:3DMM"
/db_xref="UniProtKB/Swiss-Prot:P10300"
/protein_id="CAA30537.1"
/translation="MQPWLWLVFSMKLAALWSSSALIQTPSSLLVQTNHTAKMSCEVK
SISKLTSIYWLRERQDPKDKYFEFLASWSSSKGVLYGESVDKKRNIILESSDSRRPFL
SIMNVKPEDSDFYFCATVGSPKMVFGTGTKLTVVDVLPTTAPTKKTTLKMKKKKQCPF
PHPETQKGLTCSLTTLSLLVVCILLLLAFLGVAVYFYCVRRRARIHFMKQFHK"
sig_peptide 50..112
/note="leader peptide (AA -21 to -1)"
mat_peptide 113..688
/note="mat. CD8 Ly-3 chain (AA 1-192)"
BASE COUNT 288 a 296 c 273 g 254 t
ORIGIN
1 tttcagttga cagagcactg aggggaacag tgtccccaaa agcgccaaga tgcagccatg
61 gctctggctg gtcttcagta tgaagctggc agctctctgg agcagctctg ccctcattca
121 gaccccttcg tccctgctgg ttcaaaccaa ccatacggca aagatgtcct gtgaggttaa
181 aagcatctct aagttaacaa gcatctactg gctgcgggag cgccaggacc ccaaggacaa
241 gtactttgag ttcctggcct cctggagttc ttccaaagga gttttgtatg gtgaaagtgt
301 ggacaagaaa agaaatataa ttcttgagtc ttcagactca agacggccct ttctcagtat
361 catgaatgtg aagccagagg acagtgactt ctacttctgc gcgacggttg ggagccccaa
421 gatggtcttt gggacaggga cgaagctgac tgtggttgat gtccttccta caactgcccc
481 aaccaagaag actaccctga agatgaagaa gaagaagcaa tgcccgttcc cccacccaga
541 gacccagaag ggcctgacat gcagccttac caccctcagc ctgctggtag tctgcatcct
601 gcttctgctg gcattcctcg gagtggccgt ctacttttac tgtgtgcgga ggagagcccg
661 aattcacttc atgaaacagt ttcacaaatg atcagcgccc acaacactga tagcctgcta
721 gcaataaaag gactgtaact caatcaaagc aagatttgaa ctagtgagag acagcgcatt
781 caagactgga gaggcccttg cccttgctca agctgcctgc tttgaactgc tgcaagctct
841 gtgtgtggtc tggggtctca cagggaaggc cccagaaccc aagctcactc acagagtggc
901 tgaagaacca agaactccca caccaccatg tactcttctt ggactgggcc ttggacagtg
961 gccttccagc cactgtcttt gtcagttgct tggtatgaca gccttattga ctctttggcc
1021 tttcatggaa aagagctagc cgggaccctg gagaagactg caaatcctca cacagagaag
1081 ccacctcatg aataaagttt tctgcaaaca g
//