LOCUS X06180 1656 bp mRNA linear HUM 18-APR-2005
DEFINITION Human mRNA for CD7 antigen (gp40).
ACCESSION X06180
VERSION X06180.1
KEYWORDS CD7 antigen; cell surface glycoprotein; signal peptide; T-cell
leukemia antigen.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1656)
AUTHORS Aruffo A.
TITLE Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a
COS cell expression system
JOURNAL EMBO J. 6(11), 3313-3316(1987).
PUBMED 3501369
FEATURES Location/Qualifiers
source 1..1656
/db_xref="H-InvDB:HIT000321161"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
sig_peptide 58..132
/note="put.signal peptide (AA -25 to -1)"
CDS join(58..139,570..1210)
/note="CD7 antigen"
/db_xref="GOA:P09564"
/db_xref="H-InvDB:HIT000321161.12"
/db_xref="HGNC:HGNC:1695"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013106"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036179"
/db_xref="InterPro:IPR039090"
/db_xref="UniProtKB/Swiss-Prot:P09564"
/protein_id="CAA29546.1"
/translation="MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASV
NITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMH
RLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSA
LPDPQTASALPDPPAASALPAALAVISFLLGLGLGVACVLARTQIKKLCSWRDKNSAA
CVVYEDMSHSRCNTLSSPNQYQ"
mat_peptide join(133..139,570..1207)
/note="mature CD7 antigen"
intron 140..569
/note="intron I"
misc_feature 620..628
/note="pot.N-linked glycosylation site"
misc_feature 773..781
/note="pot.N-linked glycostylation site"
misc_feature 1029..1090
/note="put.transmembrane domain"
misc_feature 1637..1642
/note="polyA signal"
polyA_site 1656..1656
/note="polyA site"
BASE COUNT 293 a 614 c 479 g 270 t
ORIGIN
1 tagacccaga gaggctcagc tgcactcgcc cggctgggag agctgggtgt ggggaacatg
61 gccgggcctc cgaggctcct gctgctgccc ctgcttctgg cgctggctcg cggcctgcct
121 ggggccctgg ctgcccaagg taagagcttc ccaggctctc catggccaca gctccggagc
181 tctccctgcc ccatgagctc agagccccca gtctgagcca cagcacagcc cccaggaagc
241 gggtggggtg ctgagcggcc tccagtgtct gaggactcat ttaagagaag gaaaaagggt
301 ggacccggtg gggagtggcc ggggctgtcc aggcagggcc gctgctttgg gaggaagaag
361 cccacagtct cggaacacga ggacagcacc tcccccaaca ccacagccgg tgcccagatc
421 tgctccatgc cccgtaaggc accgtgtctt tggcgacatg tcagccctgg gctgtctcag
481 ggccccacca tccccaccac tgtcccctgc agggaggaca ttctctgtcc ttctggccag
541 actgatggtg acagcccagg tcctcccaga ggtgcagcag tctccccact gcacgactgt
601 ccccgtggga gcctccgtca acatcacctg ctccaccagc gggggcctgc gtgggatcta
661 cctgaggcag ctcgggccac agccccaaga catcatttac tacgaggacg gggtggtgcc
721 cactacggac agacggttcc ggggccgcat cgacttctca gggtcccagg acaacctgac
781 tatcaccatg caccgcctgc agctgtcgga cactggcacc tacacctgcc aggccatcac
841 ggaggtcaat gtctacggct ccggcaccct ggtcctggtg acagaggaac agtcccaagg
901 atggcacaga tgctcggacg ccccaccaag ggcctctgcc ctccctgccc caccgacagg
961 ctccgccctc cctgacccgc agacagcctc tgccctccct gacccgccag cagcctctgc
1021 cctccctgcg gccctggcgg tgatctcctt cctcctcggg ctgggcctgg gggtggcgtg
1081 tgtgctggcg aggacacaga taaagaaact gtgctcgtgg cgggataaga attcggcggc
1141 atgtgtggtg tacgaggaca tgtcgcacag ccgctgcaac acgctgtcct cccccaacca
1201 gtaccagtga cccagtgggc ccctgcacgt cccgcctgtg gtccccccag caccttccct
1261 gccccaccat gccccccacc ctgccacacc cctcaccctg ctgtcctccc acggctgcag
1321 cagagtttga agggcccagc cgtgcccagc tccaagcaga cacacaggca gtggccaggc
1381 cccacggtgc ttctcagtgg acaatgatgc ctcctccggg aagccttccc tgcccagccc
1441 acgccgccac cgggaggaag cctgactgtc ctttggctgc atctcccgac catggccaag
1501 gagggctttt ctgtgggatg ggcctggcac gcggccctct cctgtcagtg ccggcccacc
1561 caccagcagg cccccaaccc ccaggcagcc cggcagagga cgggaggaga ccagtccccc
1621 acccagccgt accagaaata aaggcttctg tgcttc
//