LOCUS X02751 2436 bp mRNA linear HUM 23-OCT-2008
DEFINITION Human N-ras mRNA and flanking regions.
ACCESSION X02751
VERSION X02751.1
KEYWORDS oncogene; ras oncogene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2436)
AUTHORS Hall A., Brown R.
TITLE Human N-ras: cDNA cloning and gene structure
JOURNAL Nucleic Acids Res. 13(14), 5255-5268(1985).
PUBMED 2991860
COMMENT Data kindly reviewed (26-JUN-1986) by R. Brown
FEATURES Location/Qualifiers
source 1..2436
/db_xref="H-InvDB:HIT000320943"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
repeat_region 296..301
/note="GGGCGG with pot. regulatory function"
misc_feature 464..477
/note="palindrome"
repeat_region 464..470
/note="imp. inverted repeat A"
repeat_region 471..477
/note="imp. inverted repeat A"
misc_feature 474..478
/note="transcription start site"
misc_feature 484..488
/note="alternative transcription start site"
repeat_region 493..498
/note="GGGCGG with pot. regulatory function"
repeat_region 549..554
/note="GGGCGG with pot. regulatory function"
repeat_region 591..596
/note="GGGCGG with pot. regulatory function"
misc_feature 709..710
/note="exon 1/exon 2 boundary"
CDS 727..1296
/note="N-ras gene product (aa 1-189)"
/db_xref="GOA:P01111"
/db_xref="H-InvDB:HIT000320943.14"
/db_xref="HGNC:HGNC:7989"
/db_xref="InterPro:IPR001806"
/db_xref="InterPro:IPR005225"
/db_xref="InterPro:IPR020849"
/db_xref="InterPro:IPR027417"
/db_xref="PDB:2N9C"
/db_xref="PDB:3CON"
/db_xref="PDB:5UHV"
/db_xref="UniProtKB/Swiss-Prot:P01111"
/protein_id="CAA26529.1"
/translation="MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQV
VIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKR
VKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLV
REIRQYRMKKLNSSDDGTQGCMGLPCVVM"
misc_feature 837..838
/note="exon 2/exon 3 boundary"
misc_feature 1016..1017
/note="exon 3/exon 4 boundary"
misc_feature 1176..1177
/note="exon 4/exon 5 boundary"
misc_feature 1300..1301
/note="exon 5/exon 6 boundary"
misc_feature 1339..1340
/note="exon 6/exon 7 boundary"
misc_feature 2416..2421
/note="pot. polyadenylation signal"
polyA_site 2436..2436
/note="polyadenylation site"
BASE COUNT 670 a 477 c 543 g 746 t
ORIGIN
1 ctgcagcttc taggacccgg tttcttttac tgatttaaaa acaaaacaaa aaaaaataaa
61 aaagttgtgc ctgaaatgaa tcttgttttt tttttataag tagccgcctg gttactgtgt
121 cctgtaaaat acagacattg acccttggtg tagcttctgt tcaactttat atcacgggaa
181 tggatgggtc tgatttcttg gccctcttct tgaattggcc atatacaggg tccctggcca
241 gtggactgaa ggctttgtct aagatgacaa gggtcagctc aggggatgtg ggggagggcg
301 gttttatctt cccccttgtc gtttgaggtt ttgatctctg ggtaaagagg ccgtttatct
361 ttgtaaacac gaaacatttt tgctttctcc agttttctgt taatggcgaa agaatggaag
421 cgaataaagt tttactgatt tttgagacac tagcacctag cgctttcatt attgaaacgt
481 cccgtgtggg aggggcgggt ctgggtgcgg ctgccgcatg actcgtggtt cggaggccca
541 cgtggccggg gcggggactc aggcgcctgg cagccgactg attacgtagc gggcggggcc
601 ggaagtgccg ctccttggtg ggggctgttc atggcggttc cggggtctcc aacatttttc
661 ccggtctgtg gtcctaaatc tgtccaaagc agaggcagtg gagcttgagg ttcttgctgg
721 tgtgaaatga ctgagtacaa actggtggtg gttggagcag gtggtgttgg gaaaagcgca
781 ctgacaatcc agctaatcca gaaccacttt gtagatgaat atgatcccac catagaggat
841 tcttacagaa aacaagtggt tatagatggt gaaacctgtt tgttggacat actggataca
901 gctggacaag aagagtacag tgccatgaga gaccaataca tgaggacagg cgaaggcttc
961 ctctgtgtat ttgccatcaa taatagcaag tcatttgcgg atattaacct ctacagggag
1021 cagattaagc gagtaaaaga ctcggatgat gtacctatgg tgctagtggg aaacaagtgt
1081 gatttgccaa caaggacagt tgatacaaaa caagcccacg aactggccaa gagttacggg
1141 attccattca ttgaaacctc agccaagacc agacagggtg ttgaagatgc tttttacaca
1201 ctggtaagag aaatacgcca gtaccgaatg aaaaaactca acagcagtga tgatgggact
1261 cagggttgta tgggattgcc atgtgtggtg atgtaacaag atacttttaa agttttgtca
1321 gaaaagagcc actttcaagc tgcactgaca ccctggtcct gacttcctgg aggagaagta
1381 ttcctgttgc tgtcttcagt ctcacagaga agctcctgct acttccccag ctctcagtag
1441 tttagtacaa taatctctat ttgagaagtt ctcagaataa ctacctcctc acttggctgt
1501 ctgaccagag aatgcacctc ttgttactcc ctgttatttt tctgccctgg gttcttccac
1561 agcacaaaca cacctcaaca cacctctgcc accccaggtt tttcatctga aaagcagttc
1621 atgtctgaaa cagagaacca aaccgcaaac gtgaaattct attgaaaaca gtgtcttgag
1681 ctctaaagta gcaactgctg gtgatttttt ttttcttttt actgttgaac ttagaactat
1741 gcctaatttt tggagaaatg tcataaatta ctgttttgcc aagaatatag ttattattgc
1801 tgtttggttt gtttataatg ttatcggctc tattctctaa actggcatct gctctagatt
1861 cataaataca aaaatgaata ctgaattttg agtctatcct agtcttcaca actttgacgt
1921 aattaaatcc aacttttcac agtgaagtgc ctttttccta gaagtggttt gtagactcct
1981 ttataatatt tcagtggaat agatgtctca aaaatcctta tgcatgaaat gaatgtctga
2041 gatacgtctg tgacttatct accattgaag gaaagctata tctatttgag agcagatgcc
2101 attttgtaca tgtatgaaat tggttttcca gaggcctgtt ttggggcttt cccaggagaa
2161 agatgaaact gaaagcatat gaataatttc acttaataat ttttacctaa tctccacttt
2221 tttcataggt tactacctat acaatgtatg taatttgttt cccctagctt actgataaac
2281 ctaatattca atgaacttcc atttgtattc aaatttgtgt cataccagaa agctctacat
2341 ttgcagatgt tcaaatattg taaaactttg gtgcattgtt atttaatagc tgtgatcagt
2401 gattttcaaa cctcaaatat agtatattaa caaatt
//