LOCUS HSU05259 5670 bp DNA linear HUM 04-AUG-1994
DEFINITION Human MB-1 gene, complete cds.
ACCESSION U05259
VERSION U05259.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5641)
AUTHORS Ha,H., Barnoski,B.L., Sun,L., Emanuel,B.S. and Burrows,P.D.
TITLE Structure, chromosomal localization, and methylation pattern of the
human mb-1 gene
JOURNAL J. Immunol. 152 (12), 5749-5757 (1994)
PUBMED 8207205
REFERENCE 2 (bases 670 to 781; 2385 to 2684; 2926 to 3044; 4059 to 4128;
4256 to 4758)
AUTHORS Ha,H.J., Kubagawa,H. and Burrows,P.D.
TITLE Molecular cloning and expression pattern of a human gene homologous
to the murine mb-1 gene
JOURNAL J. Immunol. 148 (5), 1526-1531 (1992)
PUBMED 1538135
REFERENCE 3 (bases 1 to 5670)
AUTHORS Burrows,P.D.
TITLE Direct Submission
JOURNAL Submitted (20-JAN-1994) Peter D. Burrows, University of Alabama at
Birmingham, Microbiology, UAB Station, Birmingham, AL 35294, USA
FEATURES Location/Qualifiers
source 1..5670
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.2-13.3"
/clone="HMB1"
/sex="male"
/tissue_type="placenta"
/clone_lib="946205-Stratagene, La Jolla, CA"
/dev_stage="fetus"
regulatory 1..666
/regulatory_class="promoter"
protein_bind 287
/bound_moiety="early B cell factor (EBF)"
protein_bind 476
/bound_moiety="early B cell factor (EBF)"
protein_bind 612
/bound_moiety="SP1"
protein_bind 621
/bound_moiety="Ets-1"
protein_bind 628
/bound_moiety="SP1"
mRNA join(<667..781,2385..2684,2926..3044,4059..4127,
4255..4758)
exon <667..781
/number=1
gene join(703..781,2385..2684,2926..3044,4059..4127,4255..4368)
/gene="MB-1"
CDS join(703..781,2385..2684,2926..3044,4059..4127,4255..4368)
/gene="MB-1"
/codon_start=1
/protein_id="AAA20495.1"
/translation="MPGGPGVLQALPATIFLLFLLSAVYLGPGCQALWMHKVPASLMV
SLGEDAHFQCPHNSSNNANVTWWRVLHGNYTWPPEFLGPGEDPNGTLIIQNVNKSHGG
IYVCRVQEGNESYQQSCGTYLRVRQPPPRPFLDMGEGTKNRIITAEGIILLFCAVVPG
TLLLFRKRWQNEKLGLDAGDEYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGSLNI
GDVQLEKP"
intron 782..2384
/number=1
exon 2385..2684
/gene="MB-1"
/number=2
intron 2685..2925
/number=2
exon 2926..3044
/gene="MB-1"
/number=3
intron 3045..4958
/number=3
exon 4059..4127
/gene="MB-1"
/number=4
intron 4128..4254
/number=4
exon 4255..4758
/number=5
BASE COUNT 1267 a 1630 c 1616 g 1157 t
ORIGIN
1 cagtaaagag ctgatcatgg ttctcactcc ttgaatacca ggaacaccat ctcgtatcac
61 ataatgagac agggagacat tctggtcctc atctcacaga tgaaaaatgt caagcttcga
121 aggatcaaag tgcccaccta gtcacacggg tagtcagcca caggtcagcc tgccttattt
181 attcttcatg agtatttata gtgactaaca tttactgggc gcctactgtg ggccatttct
241 gtgcatgtga caaccccttt aagtccttgt ttctaatccc aagaagcaag gaaatggggt
301 cagggaaggg acaaggtttg cccaagtcca ggcaggggga gaggtcaagc tcagaaccat
361 cacctgccca tgacacatgc ccaggactca ggttccctag gcttccttcc aaaggctcag
421 cagtgacgag ccagcccttg aaccagcctc ttcccccacc caagcagcca cctctcaggg
481 gaattgtggc caccacaggt gcagggagca gtttctctcc actcacagcc tgaagcatac
541 ccggcagggg ctgtccccag gcccaacaag caaagggccc agtagcgagg gccactggag
601 cccatctccg gggggctggg caggaagtag ggtggggttt ggggtaggga tctggtaccc
661 tgggactgct gcaactcaaa ctaaccaacc cactgggaga agatgcctgg gggtccagga
721 gtcctccaag ctctgcctgc caccatcttc ctcctcttcc tgctgtctgc tgtctacctg
781 ggtatgtggc caaagggcag gaactggcgg gaggtggggg aagctgtgga ggctgcagag
841 agggcacagg cagagggaag ggggctcagg gaaaggggaa gaggaggcag aggatagggg
901 acccagggaa gatgcctata gaaatcgtat ctgtgccaag atgggccaag gtggggctgg
961 agggagccca gcagaggaga aggggcgtcc acagtctcac acagggaggc aggagcaaga
1021 gtcacctccc ccacctcctg ttccccacag gccaaaataa ggaactaaag ttgctcttga
1081 ctgagcacca gggctggggg caggaagggg acttaggggt agcagcattc agcgtctgtc
1141 aaggggagaa aaagctttct ctgccttaaa cctcaggtgc ctctctctgt tgggagtccc
1201 ttctcagcac tgggggaatg ggtgtctcat ggactccccc tcacctgctc aaggacagct
1261 ggcaggggct gtggcacgct aacccaggag ttcagagaaa aaggttcccc acccaaggga
1321 cactgggagc aaggattgga gttcacgtct gagtcttaag cccgtgacga tgagggtgct
1381 cggcccctct ccccatctct tcctccttct ctcttcctca cctccctcct ccacctacct
1441 ccagaagagg ggactggcca tgtgggaggc ctggctgaga gctggggctt cccagaggag
1501 cccggattgg acactgcagc cagcctgagc cgcctcgtct cactcagaga cacccccagt
1561 ctccaccccg ctctgagccc cttcaatcac cagcagccca gcccaaggac tgaactcacc
1621 cctgacccct aggttgacac atacaactta cagagaatga gggccaggca cagggtcaca
1681 ggccagggca ggccacagac tggctcctca gcccaggcag ggagaggcca gggagccaag
1741 agtttgaacc cagtgccact cctgactgcc tggtgatgct ggcaacccgc ctgccctccc
1801 agagcctcag ccatccctcc tgtaaaatgg ggctaaggag agaacctact tctagggttc
1861 tgtgaatgat tacacaagaa aaagcgccag gtgctgggcc tggctgaggc tggggtgcaa
1921 aaatggaccg ggaaggctgc gggaggaggg gacgcctgca ctgcttctgg aaggagctgt
1981 ctggacagcg tcctccagtg cctggaacaa acatccaaaa tccagagagt tcacagggcc
2041 agagtacaaa gtgggtatgc gggaggggga caagagatgg cgctgcagag gtgagaaggg
2101 cctcccaggg gtcttaccat cccagggagt ctcattctcc tctcccagga tatcctcacc
2161 caccccaacc aggtatgtcc tctctccttc ccaggggctt cttcactttc ccgcatcccc
2221 cctctcccca ggatgtatca gcccctgtca ggggctctct ctctccctcc ccacccagga
2281 gagtcctcac cctcttccca ggagtgctgg aactgcaggg gccagggctg gggaaatgtg
2341 tcaccatccc cagtccctga cccacccacc ctgtctctcc acaggccctg ggtgccaggc
2401 cctgtggatg cacaaggtcc cagcatcatt gatggtgagc ctgggggaag acgcccactt
2461 ccaatgcccg cacaatagca gcaacaacgc caacgtcacc tggtggcgcg tcctccatgg
2521 caactacacg tggccccctg agttcttggg cccgggcgag gaccccaatg gtacgctgat
2581 catccagaat gtgaacaaga gccatggggg catatacgtg tgccgggtcc aggagggcaa
2641 cgagtcatac cagcagtcct gcggcaccta cctccgcgtg cgccgtgagt ggcccagccc
2701 tggcccctac tcccactgtc ccgctgggca ctcggtttat ctttgaagtg gggatagagc
2761 cagtaccttc aatgtgggtt tcaaaccggc ttggacagag ggacggacat tctcctctgc
2821 agagtggggt ctctgggggg tctggggcct tgcaggaggt gggcggggca ggaggctagg
2881 gagggcaaga ggggccaggg ctctgagcat actacctcct tgcagagccg ccccccaggc
2941 ccttcctgga catgggggag ggcaccaaga accgaatcat cacagccgag gggatcatcc
3001 tcctgttctg cgcggtggtg cctgggacgc tgctgctgtt cagggtgagc cccctcggac
3061 ctctgagtca gccgggcgag ggctgggcga gggaccccca atacccaggt agccctctag
3121 agcctgaggt tccccatcca aaacttggga gaatgaaagc acccaccata taggggctgt
3181 gggagttaaa tgaatgaata taaagaaggg acttgaactg gcgctgagcc agggggtgtc
3241 ttcaatttag tttccccttc tggctgtcct cacgtccacc tccccccaag aagagtctca
3301 ttcttctccc taagagtgtc ctcactcccc tcctgccctc acccaggagt gtggttaccc
3361 tccaggtgta gccaagacca gggaaggtgg ggcctggtcc tcccagaatc tctgatctgt
3421 accagcctct ccttaggcac tacagaaagt gtgactgtta ttgttattat tcatggagaa
3481 tagtaaggga gtggagactc aagaagacgc tagcttggga ggccgaggca agaggatcac
3541 ttgaggccac aagtttgaga ccagcctggg caacacagca agaccctatc tctacacaca
3601 caaagtctta aaaaaaaatt agccaggcat ggtggcacac acctatagtc ccagctactc
3661 aggaggctga ggtgggagga ttgcttgagc ccaggagttc aaggctgcag tgaaatatga
3721 tgttgccaca gcacttccag cctgggcaac tgagggagaa gaaagagaga gagagagaaa
3781 gagagagaga gagagagaga gagagagagg gccagaggga gggagggaag gaagggaagg
3841 gaagggaagg aaggaaggaa ggaaggaagg aaggaaggaa ggaaggaagg aaggagaaca
3901 ctggttgtag actcagagag aactgttaca taaccagtat gtggccttgg ggacatctct
3961 taccctttct ggaaaagtac ttcctggcat ccaggagggt ctgaaagata ttcacctccc
4021 cctgctcact gaggcaccca ccccacccac ccctacagaa acgatggcag aacgagaagc
4081 tcgggttgga tgccggggat gaatatgaag atgaaaacct ttatgaagtg agtgaagggt
4141 ggggatgggg taggggcagt tgtgttaggg gtgggggtgt tcctctgggg gtggctgggg
4201 gcagggaccc caggtgtcag ggtgctgatg ttcgctgcct catttccatc ccagggcctg
4261 aacctggacg actgctccat gtatgaggac atctcccggg gcctccaggg cacctaccag
4321 gatgtgggca gcctcaacat aggagatgtc cagctggaga agccgtgaca cccctactcc
4381 tgccaggctg cccccgcctg ctgtgcaccc agctccagtg tctcagctca cttccctggg
4441 acattctcct ttcagccctt ctgggggctt ccttagtcat attcccccag tggggggtgg
4501 gagggtaacc tcactcttct ccaggccagg cctccttgga ctcccctggg ggtgtcccac
4561 tcttcttccc tctaaactgc cccacctcct aacctaatcc ccacgccccg ctgcctttcc
4621 caggctcccc tcacccagcg ggtaatgagc ccttaatcgc tgcctctagg ggagctgatt
4681 gtagcagcct cgttagtgtc accccctcct ccctgatctg tcagggccac ttagtgataa
4741 taaattcttc ccaactgcag accttggcag gagtcgtgga tcttacggaa accgcctctc
4801 ccacatgtcc ctcagaccca ggagtcccag cccaagccac tccctgccca ctccccacac
4861 ctgggaccag gtagccagtc tgggctgccc tcctgggaga acaagatgtc tcttgggaag
4921 gtccccagac caactgaagg actggtttgg ccctctttgc agggctcacc ctagggtcat
4981 atccttaagc aagaaggggg acaagatcaa gatggctgtg gctaccaaat tacttacact
5041 tttttttttt tttttttttt ttgagacaga gtctcactct gttgcccagg ttggagtgct
5101 cactgcaacc tctgcctcct gggttcaagc gattctcctg cctcagcctc ccaagtagct
5161 gggattacag gcgcctgcca ccatgcccag ctaatttttg tatttttagt agaggcgggg
5221 tttcaccatg ttggccagac tggtcttgaa cctctgacct caggtgatcc acctaccttg
5281 gcctcccaaa gtgctgggat tacaggcgcc tgcaccacgc ccggccgctt tttttttttt
5341 tttttttttt tgaggcagag tctgactctg tcgcccaggc tggagtgcag tggcgcaatc
5401 tcagcccact tcaacctcca cctcaagcga ttcttgtacc tcaggctccc gagtagctgg
5461 gatgacaggc atgtgctacc acacccagct aatttttgtt ttagtagaga cagggtttcg
5521 ccatgttggc cgggctggtc tcgaactcct gacctcaagt gatccaccat gcttcggcct
5581 cccaaagtgc tgggattaca gcatgagcca ctttatgcgt atttaagcct tggaaacaca
5641 gggactatct tgtggattgg ggctagtaca
//