LOCUS AH002809 3356 bp DNA linear HUM 01-AUG-2016
DEFINITION Homo sapiens antigen B7 (B7) gene, complete cds.
ACCESSION AH002809 M83071 M83072 M83073 M83074 M83075 M83077
VERSION AH002809.2
KEYWORDS B-lymphocyte activation antigen B7; antigen B7.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3356)
AUTHORS Selvakumar,A., Mohanraj,B.K., Eddy,R.L., Shows,T.B., White,P.C. and
Dupont,B.
TITLE Genomic organization and chromosomal location of the human gene
encoding the B-lymphocyte activation antigen B7
JOURNAL Immunogenetics 36 (3), 175-181 (1992)
PUBMED 1377173
COMMENT On or before Aug 1, 2016 this sequence version replaced M83071.1,
M83072.1, M83073.1, M83074.1, M83075.1, M83077.1, AH002809.1.
FEATURES Location/Qualifiers
source 1..3356
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/cell_type="B-lymphocyte"
gene 98..3245
/gene="B7"
mRNA join(98..272,594..893,1199..1516,1845..2126,2443..2538,
2868..3245)
/gene="B7"
/product="antigen B7"
exon 98..272
/gene="B7"
/note="putative"
/number=1
5'UTR 98..272
/gene="B7"
intron order(273..374,475..593)
/gene="B7"
/number=1
gap 375..474
/estimated_length=unknown
exon 594..893
/gene="B7"
/number=2
CDS join(794..893,1199..1516,1845..2126,2443..2538,2868..2938)
/gene="B7"
/codon_start=1
/product="antigen B7"
/protein_id="AAA58390.1"
/translation="MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKE
VATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIV
ILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRI
ICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLI
KYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRR
NERLRRESVRPV"
sig_peptide 794..871
/gene="B7"
mat_peptide join(872..893,1199..1516,1845..2126,2443..2538,2868..2935)
/gene="B7"
/product="antigen B7"
intron order(894..995,1096..1198)
/gene="B7"
/number=2
gap 996..1095
/estimated_length=unknown
exon 1199..1516
/gene="B7"
/number=3
intron order(1517..1622,1723..1844)
/gene="B7"
/number=3
gap 1623..1722
/estimated_length=unknown
exon 1845..2126
/gene="B7"
/number=4
intron order(2127..2232,2333..2442)
/gene="B7"
/number=4
gap 2233..2332
/estimated_length=unknown
exon 2443..2538
/gene="B7"
/number=5
intron order(2539..2646,2747..2867)
/gene="B7"
/number=5
gap 2647..2746
/estimated_length=unknown
exon 2868..3245
/gene="B7"
/number=6
3'UTR 2936..3245
/gene="B7"
regulatory 3228..3233
/regulatory_class="polyA_signal_sequence"
/gene="B7"
BASE COUNT 814 a 626 c 555 g 861 t
ORIGIN
1 cagcctctac aaaagcaact agaagaagac ggcagcagag ggcgcttctt caaacaccct
61 gtccaactcc tggcactgac aagtactgag tgaactcaaa ccctctgtaa agtaacagaa
121 gttagaaggg gaaatgtcgc ctctctgaag attacccaaa gaaaaagtga tttgtcattg
181 ctttatagac tgtaagaaga gaacatctca gaagtggagt cttaccctga aatcaaagga
241 tttaaagaaa aagtggaatt tttcttcagc aagtaagtac atttactatt atcttactat
301 gggatagctt ggtagaacta gttaccagca acctcactgc tttttaaaca aacaatacct
361 ctgctaccac ctccnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngcttta
481 gaggttgctt aggttaagct ctccggaagg ttttagcagg caactcgaga gttttgcaac
541 tcaaagtagg cacaccttcc ttcctgaatg acttttattt gttccttttt caggctgtga
601 aactaaatcc acaacctttg gagacccagg aacaccctcc aatctctgtg tgttttgtaa
661 acatcactgg agggtcttct acgtgagcaa ttggattgtc atcagccctg cctgttttgc
721 acctgggaag tgccctggtc ttacttgggt ccaaattgtt ggctttcact tttgacccta
781 agcatctgaa gccatgggcc acacacggag gcagggaaca tcaccatcca agtgtccata
841 cctcaatttc tttcagctct tggtgctggc tggtctttct cacttctgtt caggtaagca
901 actttcagga acttaactga gtcaactgct acagggttaa gagaaaggac atggggttct
961 ctgagctgct cccttctatt atcctataag ctggannnnn nnnnnnnnnn nnnnnnnnnn
1021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1081 nnnnnnnnnn nnnnngacac aacattttaa gttctgttac tgccgacttt ggattcctga
1141 ccatcgagga atctgtattt aataaatata caatcttgtt ctgtttgcct ctccataggt
1201 gttatccacg tgaccaagga agtgaaagaa gtggcaacgc tgtcctgtgg tcacaatgtt
1261 tctgttgaag agctggcaca aactcgcatc tactggcaaa aggagaagaa aatggtgctg
1321 actatgatgt ctggggacat gaatatatgg cccgagtaca agaaccggac catctttgat
1381 atcactaata acctctccat tgtgatcctg gctctgcgcc catctgacga gggcacatac
1441 gagtgtgttg ttctgaagta tgaaaaagac gctttcaagc gggaacacct ggctgaagtg
1501 acgttatcag tcaaaggttg gtgggatttt ctgattttac tctaggccgg cagattctta
1561 atgcccttaa agacacatgg ctattgattt aggtgaaaat tttaccaaag agggatgtat
1621 ctnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncccgatat atatcctctc
1741 ccctttatca attcttatta aagctagaaa attatttaaa aataaacctc tacacacata
1801 ggtttctaag tatacgtaat tatatattct tgttctttct ttagctgact tccctacacc
1861 tagtatatct gactttgaaa ttccaacttc taatattaga aggataattt gctcaacctc
1921 tggaggtttt ccagagcctc acctctcctg gttggaaaat ggagaagaat taaatgccat
1981 caacacaaca gtttcccaag atcctgaaac tgagctctat gctgttagca gcaaactgga
2041 tttcaatatg acaaccaacc acagcttcat gtgtctcatc aagtatggac atttaagagt
2101 gaatcagacc ttcaactgga atacaagtga cattgttctg gggagtttct actatatcga
2161 atctaaaaag acaatatagt cgtgtcattt aatgatgtgg atacattttg agaaatgcat
2221 cattaggcaa ttnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnacgtgacc
2341 aggcaaagaa tacctccaca gttcgatcaa tagaaaagga cagaatgagt atcaggcagt
2401 aggaaataca ttacagctga cattattctt ttccccccat agccaagcaa gagcattttc
2461 ctgataacct gctcccatcc tgggccatta ccttaatctc agtaaatgga atttttgtga
2521 tatgctgcct gacctactgt aagtactatc ataccatcat cctgatctca attctggaag
2581 atcaaacttt attaccatgg ttcggcatct ctctgaggtt ttagcctatt cgcttctcat
2641 gtttacnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnntata agaacaactg
2761 ctccagttct aagccagtct gaagccttgc taaagtaaat attaacatat gggcacaatt
2821 caagggaaac ttacttatca tttttattgt ttgttcttgt ctccaaggct ttgccccaag
2881 atgcagagag agaaggagga atgagagatt gagaagggaa agtgtacgcc ctgtataaca
2941 gtgtccgcag aagcaagggg ctgaaaagat ctgaaggtag cctccgtcat ctcttctggg
3001 atacatggat cgtggggatc atgaggcatt cttcccttaa caaatttaag ctgttttacc
3061 cactacctca ccttcttaaa aacctctttc agattaagct gaacagttac aagatggctg
3121 gcatccctct cctttctccc catatgcaat ttgcttaatg taacctcttc ttttgccatg
3181 tttccattct gccatcttga attgtcttgt cagccaattc attatctatt aaacactaat
3241 ttgagttcat cttgaatatt cctgtggtaa cttcttattc tgatcattca tttttccctc
3301 tatctctcag tattgatgga catgggttgg ggtcactttg tattaacacg gtaaca
//