LOCUS HUMCTLA4A 1664 bp DNA linear HUM 01-NOV-1994
DEFINITION Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4) gene, 5'
end.
ACCESSION M74363
VERSION M74363.1
KEYWORDS cytotoxic T-lymphocyte-associated protein 4; immunoglobulin
superfamily.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1664)
AUTHORS Harper,K., Balzano,C., Rouvier,E., Mattei,M.G., Luciani,M.F. and
Golstein,P.
TITLE CTLA-4 and CD28 activated lymphocyte molecules are closely related
in both mouse and human as to sequence, message expression, gene
structure, and chromosomal location
JOURNAL J. Immunol. 147 (3), 1037-1044 (1991)
PUBMED 1713603
FEATURES Location/Qualifiers
source 1..1664
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/map="2q33"
/cell_line="LY67"
/cell_type="cytotoxic T lymphocyte"
gene 1193..1664
/gene="CTLA4"
CDS 1193..>1301
/gene="CTLA4"
/codon_start=1
/product="cytotoxic T-lymphocyte-associated protein 4"
/protein_id="AAA52127.1"
/db_xref="GDB:G00-119-818"
/translation="MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCK"
intron 1302..>1664
/gene="CTLA4"
/note="G00-119-818"
/number=1
BASE COUNT 444 a 325 c 359 g 536 t
ORIGIN
1 ctgcagagtc tcctctgctg tgctgaggtg tggacaatgg gaaaccatgg acggactgga
61 gtaggcaaat gtcatattcc ctgttgcaac tgtctgtttg catgtcagcc ttctagaagc
121 cccttaaggt atcaactatg tttttgtttt gtcatcattc aatcctaagt gcacagaatt
181 ccgggcatat tacaggttcc ccataaatgt ttctttcttt attaaaatgt atgaaaactc
241 tccagattta aggaaggtcc tcaatgtttc aaattctttt tgttagatca gttggtcctg
301 tctacagctg tcacaaattt aaggactctg gttatattta atcttcactt ttgaattttc
361 tgcttgaaaa atttgtatta gaaaaaaaag tctatccttt tatggacggc tctaatctct
421 tgaatcattt gggttggctt ttctttggac cttcttcaac tctgttttgt ctctgttgag
481 ttaaggcttt taagaacacc tgaattcttt ccttctgcaa aaccagaggc agcttctttt
541 ccgcctattt tcagtttatt tcttgtgatt ttagtttttt tctcttaacc aaatgctaaa
601 tggatttagg agaaataaac ttatttgtaa agctgtcaag ggaccattag aaggatggtg
661 cttcacagat agaatacagt ttttattaat gatgcctaga caatcctgcc attacgcaag
721 gctcagaagt tagcagccta gtagtttgag atgtcaatga aatgaattgg actggatggt
781 taaggatgcc cagaagattg aataaaattg ggatttagga ggacccttgt actccaggaa
841 attctccaag tctccactta gttatccaga tcctcaaagt gaacatgaag cttcagtttc
901 aaattgaata cattttccat ccatggattg gcttgttttg ttcagttgag tgcttgaggt
961 tgtcttttcg acgtaacagc taaacccacg gcttcctttc tcgtaaaacc aaaacaaaaa
1021 ggctttctat tcaagagcct tctgtgtgtg cacatgtgta atacatatct ggatcaaagc
1081 tatctatata aagtccttga ttctgtgtgg gttcaaacac atttcaaagc ttcaggatcc
1141 tgaaaggttt tgctctactt cctgaagacc tgaacaccgc tcccataaag ccatggcttg
1201 ccttggattt cagcggcaca aggctcagct gaacctggct accaggacct ggccctgcac
1261 tctcctgttt tttcttctct tcatccctgt cttctgcaaa ggtgagtgag acttttggag
1321 catgaagatg gaggaggtgt ttctcctacc tgggtttcat ttgtttcagc agtcaagggc
1381 agtcatttat agcaaagcca gaagttaaag gtaaaactca atctggcttg gctggctctg
1441 tattccaggg ccagcaggga gcagttgggc gccagaataa ggcaaaagag atagctcgag
1501 aacagagcgc caggtattta gtaggggctt catgaatgca tgtgagttgg tttagtagag
1561 agacacaggc aatttcagac ccttctatga gactggaagt gatttaagag ggaaaggata
1621 gccatagtaa tgaatacatt tgagctgggt ttcaggatga gctc
//