LOCUS HUMCD1A 2072 bp mRNA linear HUM 01-NOV-1994
DEFINITION Human thymocyte antigen CD1a mRNA, complete cds.
ACCESSION M28825
VERSION M28825.1
KEYWORDS cell surface antigen.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2072)
AUTHORS Aruffo,A. and Seed,B.
TITLE Expression of cDNA clones encoding the thymocyte antigens CD1a, b,
c demonstrates a hierarchy of exclusion in fibroblasts
JOURNAL J. Immunol. 143 (5), 1723-1730 (1989)
PUBMED 2701945
COMMENT Original source text: Human, cDNA to mRNA (HPB-ALL library).
FEATURES Location/Qualifiers
source 1..2072
/db_xref="H-InvDB:HIT000195290"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1q22-q23"
gene 1..2072
/gene="CD1A"
CDS 534..1517
/gene="CD1A"
/note="CD1a antigen precursor"
/codon_start=1
/protein_id="AAA51931.1"
/db_xref="GDB:G00-120-575"
/translation="MLFLLLPLLAVLPGDGNADGLKEPLSFHVIWIASFYNHSWKQNL
VSGWLSDLQTHTWDSNSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYA
HELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKH
FCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGH
LQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADL
SCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPLLLLIGLALWFRKRCFC"
sig_peptide 534..581
/gene="CD1A"
/note="CD1a signal peptide; G00-120-575"
mat_peptide 582..1514
/gene="CD1A"
/product="CD1a antigen; G00-120-575"
BASE COUNT 530 a 444 c 522 g 576 t
ORIGIN
1 gggcagtcgt aggagactct gaaaaagcaa ataaatcaat gttaaatcag aaatgtgaat
61 gtagtaaggg gctgaagaga caggggaaga gaatacatgg gaaaatattg aaaaggacag
121 agtgatcaaa aaaagcaggg acatgggagc attgggcagc acactgggag ccatttactt
181 tatgctctta ttgtatgatt gagaaaaaaa atgtccttag tggttaagtg gcttttcaat
241 gccacatcag acttgttcca tagcagttga attaggggaa ggtgaataag ttggaggttg
301 gtgacaagga gagaagctgg aacagagagg agagtcagaa ccagagggaa atgagagact
361 gagtaggcat ctcagggttt ttgaaggagt ggattttctt tgttgcagtc aggggaggtt
421 tgtctgttgg ctgcagaaag aagtcagaat agagatatcg tggggtaggt ttgtttggaa
481 cagaaatcaa agaccaattt ttctgagaga aggaaataac atctgcaaat gatatgctgt
541 ttttgctact tccattgtta gctgttctcc caggtgatgg caatgcagac gggctcaagg
601 agcctctctc cttccatgtc atctggatcg catcctttta caaccattcc tggaaacaaa
661 atctggtctc aggttggctg agtgatttgc agactcatac ctgggacagc aattccagca
721 ccatcgtttt cctgtggccc tggtccaggg gaaacttcag caatgaggag tggaaggaac
781 tggaaacatt attccgtata cgcaccattc ggtcatttga gggaattcgt agatacgccc
841 atgaattgca gtttgaatat ccttttgaga tacaggtgac aggaggctgt gagctgcact
901 ctggaaaggt ctcaggaagc ttcttgcagt tagcttatca aggatcagac tttgtgagct
961 tccagaacaa ttcatggttg ccatatccag tggctgggaa tatggccaag catttctgca
1021 aagtgctcaa tcagaatcag catgaaaatg acataacaca caatcttctc agtgacacct
1081 gcccacgttt catcttgggt cttcttgatg caggaaaggc acatctccag cggcaagtga
1141 agcccgaggc ctggctgtcc catggcccca gtcctggccc tggccatctg cagcttgtgt
1201 gccatgtctc aggattctac ccaaagcccg tgtgggtgat gtggatgcgg ggtgagcagg
1261 agcagcaggg cactcagcga ggggacatct tgcccagtgc tgatgggaca tggtatctcc
1321 gcgcaaccct ggaggtggcc gctggggagg cagctgacct gtcctgtcgg gtgaagcaca
1381 gcagtctaga gggccaggac atcgtcctct actgggagca tcacagttcc gtgggcttca
1441 tcatcttggc ggtgatagtg cctttacttc ttctgatagg tcttgcgctt tggttcagga
1501 aacgctgttt ctgttaagac acaccatgag cctcctcgtc acccttctcc ttttggggtg
1561 agagaccagc agcccaaggg ctccagacac acctgaacac atcgtgatga tgacgtcctc
1621 tcaactctct ttgtaaaaat tttgttattt ttgcttgttt ctgattaatg attgtttgtc
1681 aatataagct caatttaatt ttgcaggatt tgttgttctg acctgggttc tgggactttt
1741 aaattcaaat tttatctcca gatggaatgg ggtcctagca acctccacat gttcacctat
1801 taatggatca tcaggcctgt tttagatatc ccttactcca gagggccttc cctgacttac
1861 aagtgggaag cagtctcttc ctggtctgaa ctcccgccac attttagccg tactttgcta
1921 actgtgctcc tcacttcctc ttcttcattg cagttattta gatcccccct ttccttctaa
1981 tttttcagct ccttcaatgc aaagtacatg tatttttaat atatgcatcc ctggtgaagg
2041 atcttgcctg catgaaacat gttctcaata aa
//