LOCUS HUMANTCD2 1504 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human surface antigen CD2 mRNA, complete cds.
ACCESSION M16445
VERSION M16445.1
KEYWORDS surface antigen.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1504)
AUTHORS Seed,B. and Aruffo,A.
TITLE Molecular cloning of the CD2 antigen, the T-cell erythrocyte
receptor, by a rapid immunoselection procedure
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (10), 3365-3369 (1987)
PUBMED 2437578
COMMENT Original source text: Human HPB-ALL T-cell leukemia cell line, cDNA
to mRNA.
Draft entry and computer-readable sequence for [1] kindly provided
by B.Seed, 13-OCT-1987. A polyadenylation signal is located at
positions 1490-1495.
FEATURES Location/Qualifiers
source 1..1504
/db_xref="H-InvDB:HIT000194449"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1p13"
gene 1..1504
/gene="CD2"
CDS 7..1062
/gene="CD2"
/note="surface antigen CD2 precursor"
/codon_start=1
/protein_id="AAA51738.1"
/db_xref="GDB:G00-118-735"
/translation="MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLD
IPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQ
DIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQ
DGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICG
GGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPQQIPASTPQNP
ATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQ
PKPPHGAAENSLSPSSN"
sig_peptide 7..63
/gene="CD2"
/note="surface antigen CD2 signal peptide"
mat_peptide 64..1059
/gene="CD2"
/product="surface antigen CD2"
BASE COUNT 462 a 356 c 328 g 358 t
ORIGIN Chromosome 1p13.
1 cctaagatga gctttccatg taaatttgta gccagcttcc ttctgatttt caatgtttct
61 tccaaaggtg cagtctccaa agagattacg aatgccttgg aaacctgggg tgccttgggt
121 caggacatca acttggacat tcctagtttt caaatgagtg atgatattga cgatataaaa
181 tgggaaaaaa cttcagacaa gaaaaagatt gcacaattca gaaaagagaa agagactttc
241 aaggaaaaag atacatataa gctatttaaa aatggaactc tgaaaattaa gcatctgaag
301 accgatgatc aggatatcta caaggtatca atatatgata caaaaggaaa aaatgtgttg
361 gaaaaaatat ttgatttgaa gattcaagag agggtctcaa aaccaaagat ctcctggact
421 tgtatcaaca caaccctgac ctgtgaggta atgaatggaa ctgaccccga attaaacctg
481 tatcaagatg ggaaacatct aaaactttct cagagggtca tcacacacaa gtggaccacc
541 agcctgagtg caaaattcaa gtgcacagca gggaacaaag tcagcaagga atccagtgtc
601 gagcctgtca gctgtccaga gaaaggtctg gacatctatc tcatcattgg catatgtgga
661 ggaggcagcc tcttgatggt ctttgtggca ctgctcgttt tctatatcac caaaaggaaa
721 aaacagagga gtcggagaaa tgatgaggag ctggagacaa gagcccacag agtagctact
781 gaagaaaggg gccggaagcc ccaacaaatt ccagcttcaa cccctcagaa tccagcaact
841 tcccaacatc ctcctccacc acctggtcat cgttcccagg cacctagtca tcgtcccccg
901 cctcctggac accgtgttca gcaccagcct cagaagaggc ctcctgctcc gtcgggcaca
961 caagttcacc agcagaaagg cccgcccctc cccagacctc gagttcagcc aaaacctccc
1021 catggggcag cagaaaactc attgtcccct tcctctaatt aaaaaagata gaaactgtct
1081 ttttcaataa aaagcactgt ggatttctgc cctcctgatg tgcatatccg tacttccatg
1141 aggtgttttc tgtgtgcaga acattgtcac ctcctgaggc tgtgggccac agccacctct
1201 gcatcttcga actcagccat gtggtcaaca tctggagttt ttggtctcct cagagagctc
1261 catcacacca gtaaggagaa gcaatataag tgtgattgca agaatggtag aggaccgagc
1321 acagaaatct tagagatttc ttgtcccctc tcaggtcatg tgtagatgcg ataaatcaag
1381 tgattggtgt gcctgggtct cactacaagc agcctatctg cttaagagac tctggagttt
1441 cttatgtgcc ctggtggaca cttgcccacc atcctgtgag taaaagtgaa ataaaagctt
1501 tgac
//