LOCUS HUMCD2A 1522 bp mRNA linear HUM 01-NOV-1994
DEFINITION Human T-cell surface antigen CD2 (T11) mRNA, complete cds, clone
PB1.
ACCESSION M16336
VERSION M16336.1
KEYWORDS CD2 surface antigen; T-cell antigen; glycoprotein; immunoglobulin
superfamily.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1522)
AUTHORS Sayre,P.H., Chang,H.C., Hussey,R.E., Brown,N.R., Richardson,N.E.,
Spagnoli,G., Clayton,L.K. and Reinherz,E.L.
TITLE Molecular cloning and expression of T11 cDNAs reveal a
receptor-like structure on human T lymphocytes
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (9), 2941-2945 (1987)
PUBMED 2883656
COMMENT Original source text: Human Jurkat cell line, cDNA to mRNA, clone
PB1.
FEATURES Location/Qualifiers
source 1..1522
/db_xref="H-InvDB:HIT000194444"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1p13"
gene 1..1522
/gene="CD2"
mRNA <1..1522
/gene="CD2"
/product="CD2 mRNA"
CDS 24..1106
/gene="CD2"
/note="CD2 surface antigen"
/codon_start=1
/protein_id="AAA51946.1"
/db_xref="GDB:G00-118-735"
/translation="MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLD
IPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQ
DIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQ
DGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICG
GGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNP
ATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQ
PKPPMGQQKTHCPLPLIKKDRNCLFQ"
sig_peptide 24..95
/gene="CD2"
/note="CD2 surface antigen signal peptide"
mat_peptide 96..1103
/gene="CD2"
/product="CD2 surface antigen"
BASE COUNT 471 a 359 c 332 g 360 t
ORIGIN Chromosome 1p13.
1 aaaagaggaa accaacccct aagatgagct ttccatgtaa atttgtagcc agcttccttc
61 tgattttcaa tgtttcttcc aaaggtgcag tctccaaaga gattacgaat gccttggaaa
121 cctggggtgc cttgggtcag gacatcaact tggacattcc tagttttcaa atgagtgatg
181 atattgacga tataaaatgg gaaaaaactt cagacaagaa aaagattgca caattcagaa
241 aagagaaaga gactttcaag gaaaaagata catataagct atttaaaaat ggaactctga
301 aaattaagca tctgaagacc gatgatcagg atatctataa ggtatcaata tatgatacaa
361 aaggaaaaaa tgtgttggaa aaaatatttg atttgaagat tcaagagagg gtctcaaaac
421 caaagatctc ctggacttgt atcaacacaa ccctgacctg tgaggtaatg aatggaactg
481 accccgaatt aaacctgtat caagatggga aacatctaaa actttctcag agggtcatca
541 cacacaagtg gaccaccagc ctgagtgcaa aattcaagtg cacagcaggg aacaaagtca
601 gcaaggaatc cagtgtcgag cctgtcagct gtccagagaa aggtctggac atctatctca
661 tcattggcat atgtggagga ggcagcctct tgatggtctt tgtggcactg ctcgttttct
721 atatcaccaa aaggaaaaaa cagaggagtc ggagaaatga tgaggagctg gagacaagag
781 cccacagagt agctactgaa gaaaggggcc ggaagcccca ccaaattcca gcttcaaccc
841 ctcagaatcc agcaacttcc caacatcctc ctccaccacc tggtcatcgt tcccaggcac
901 ctagtcatcg tcccccgcct cctggacacc gtgttcagca ccagcctcag aagaggcctc
961 ctgctccgtc gggcacacaa gttcaccagc agaaaggccc gcccctcccc agacctcgag
1021 ttcagccaaa acctcccatg gggcagcaga aaactcattg tccccttcct ctaattaaaa
1081 aagatagaaa ctgtcttttt caataaaaag cactgtggat ttctgccctc ctgatgtgca
1141 tatccgtact tccatgaggt gttttctgtg tgcagaacat tgtcacctcc tgaggctgtg
1201 ggccacagcc acctctgcat cttcgaactc agccatgtgg tcaacatctg gagtttttgg
1261 tctcctcaga gagctccatc acaccagtaa ggagaagcaa tataagtgtg attgcaagaa
1321 gtgtagagga ccgagccaga aatcttagag atttcttgtc ccctctcagg tcatgtgtag
1381 atgcgataaa tcaagtgatt ggtgtgcctg ggtctcacta caagcagcct atctgcttaa
1441 gagactctgg agtttcttat gtgccctggt ggacacttgc ccaccatcct gtgagtaaaa
1501 gtgaaataaa agctttgact ag
//