LOCUS HUMBGPI 2197 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human biliary glycoprotein I (BGP I) mRNA, complete cds.
ACCESSION J03858
VERSION J03858.1
KEYWORDS biliary glycoprotein a; carcinoembryonic gene family; transmembrane
protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2197)
AUTHORS Hinoda,Y., Neumaier,M., Hefta,S.A., Drzeniek,Z., Wagener,C.,
Shively,L., Hefta,L.J., Shively,J.E. and Paxton,R.J.
TITLE Molecular cloning of a cDNA coding biliary glycoprotein I: primary
structure of a glycoprotein immunologically crossreactive with
carcinoembryonic antigen
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (18), 6959-6963 (1988)
PUBMED 2457922
REMARK Erratum:[Proc Natl Acad Sci U S A 1989 Mar;86(5):1668]
REFERENCE 2 (bases 1482 to 1483)
AUTHORS Hinoda,Y., Neumaier,M., Hefta,S.A., Drzeniek,Z., Wagner,C.,
Shively,L., Hefta,L.J.F., Shively,J.E. and Paxton,R.J.
TITLE Medical Sciences: Correction
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 1668-1668 (1989)
COMMENT Original source text: Human adult colon epithilial cell, cDNA to
mRNA, clones [4,26,36,18].
[2] revises [1]; c -> ag.
Draft entry and computer-readable sequence for [1] kindly provided
by R.J.Paxton, 18-JAN-1989.
FEATURES Location/Qualifiers
source 1..2197
/db_xref="H-InvDB:HIT000191213"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="19q13.2"
gene 1..2197
/gene="BGP"
CDS 82..1662
/gene="BGP"
/note="biliary glycoprotein I precursor"
/codon_start=1
/protein_id="AAA51826.1"
/db_xref="GDB:G00-127-992"
/translation="MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFN
VAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIY
PNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDK
DAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQ
NPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGT
FQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASK
TTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAG
TYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALAC
FLHFGKTGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLNFEAQQPTQPTS
ASPSLTATEIIYSEVKKQ"
sig_peptide 82..183
/gene="BGP"
/note="biliary glycoprotein I signal peptide"
mat_peptide 184..1659
/gene="BGP"
/product="biliary glycoprotein I"
BASE COUNT 616 a 649 c 456 g 476 t
ORIGIN 462 bp upstream of BglII site.
1 gtgacagagc agccgtgctc gaagcgttcc tggagcccaa gctctcctcc acaggtgaag
61 acagggccag caggagacac catggggcac ctctcagccc cacttcacag agtgcgtgta
121 ccctggcagg ggcttctgct cacagcctca cttctaacct tctggaaccc gcccaccact
181 gcccagctca ctactgaatc catgccattc aatgttgcag aggggaagga ggttcttctc
241 cttgtccaca atctgcccca gcaacttttt ggctacagct ggtacaaagg ggaaagagtg
301 gatggcaacc gtcaaattgt aggatatgca ataggaactc aacaagctac cccagggccc
361 gcaaacagcg gtcgagagac aatatacccc aatgcatccc tgctgatcca gaacgtcacc
421 cagaatgaca caggattcta caccctacaa gtcataaagt cagatcttgt gaatgaagaa
481 gcaactggac agttccatgt atacccggag ctgcccaagc cctccatctc cagcaacaac
541 tccaaccctg tggaggacaa ggatgctgtg gccttcacct gtgaacctga gactcaggac
601 acaacctacc tgtggtggat aaacaatcag agcctcccgg tcagtcccag gctgcagctg
661 tccaatggca acaggaccct cactctactc agtgtcacaa ggaatgacac aggaccctat
721 gagtgtgaaa tacagaaccc agtgagtgcg aaccgcagtg acccagtcac cttgaatgtc
781 acctatggcc cggacacccc caccatttcc ccttcagaca cctattaccg tccaggggca
841 aacctcagcc tctcctgcta tgcagcctct aacccacctg cacagtactc ctggcttatc
901 aatggaacat tccagcaaag cacacaagag ctctttatcc ctaacatcac tgtgaataat
961 agtggatcct atacctgcca cgccaataac tcagtcactg gctgcaacag gaccacagtc
1021 aagacgatca tagtcactga gctaagtcca gtagtagcaa agccccaaat caaagccagc
1081 aagaccacag tcacaggaga taaggactct gtgaacctga cctgctccac aaatgacact
1141 ggaatctcca tccgttggtt cttcaaaaac cagagtctcc cgtcctcgga gaggatgaag
1201 ctgtcccagg gcaacaccac cctcagcata aaccctgtca agagggagga tgctgggacg
1261 tattggtgtg aggtcttcaa cccaatcagt aagaaccaaa gcgaccccat catgctgaac
1321 gtaaactata atgctctacc acaagaaaat ggcctctcac ctggggccat tgctggcatt
1381 gtgattggag tagtggccct ggttgctctg atagcagtag ccctggcatg ttttctgcat
1441 ttcgggaaga ccggcagggc aagcgaccag cgtgatctca cagagcacaa accctcagtc
1501 tccaaccaca ctcaggacca ctccaatgac ccacctaaca agatgaatga agttacttat
1561 tctaccctga actttgaagc ccagcaaccc acacaaccaa cttcagcctc cccatcccta
1621 acagccacag aaataattta ttcagaagta aaaaagcagt aatgaaacct gtcctgctca
1681 ctgcagtgct gatgtatttc aagtctctca ccctcatcac taggagattc ctttccctgt
1741 aggggtagag gggtggggac agaaacaact ttctcctact cttccttcct aataggcatc
1801 tccaggctgc ctggtcactg cccctctctc agtgtcaata gatgaaagta cattgggagt
1861 ctgtaggaaa cccaaccttc ttgtcattga aatttggcaa agctgacttt gggaaagagg
1921 gaccagaact tcccctccct tccccttttc ccaacctgga cttgttttaa acttgcctgt
1981 tcagagcact cattccttcc cacccccagt cctgtcctat cactctaatt cggatttgcc
2041 atagccttga ggttatgtcc ttttccatta agtacatgtg ccaggaaaca agagagagag
2101 aaagtaaagg cagtaatgcc ttctcctatt tctccaaagc cttgtgtgaa ctcaccaaac
2161 acaagaaaat ctaaatatat aaccaatagt gaaatgc
//