LOCUS YSCPDR1 4339 bp DNA linear PLN 27-APR-1993
DEFINITION Yeast (S.cerevisiae) PDR1 gene encoding multidrug resistance,
complete cds.
ACCESSION J03487
VERSION J03487.1
KEYWORDS multidrug resistance.
SOURCE Saccharomyces cerevisiae (brewer's yeast)
ORGANISM Saccharomyces cerevisiae
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 4339)
AUTHORS Balzi,E., Chen,W., Ulaszewski,S., Capieaux,E. and Goffeau,A.
TITLE The multidrug resistance gene PDR1 from Saccharomyces cerevisiae
JOURNAL J. Biol. Chem. 262 (35), 16871-16879 (1987)
PUBMED 3316228
COMMENT Original source text: Yeast (S.cerevisiae, strain IL125-2B) DNA,
clone pA-B6.5.
Draft entry and computer-readable sequence for [1] kindly provided
by E.Balzi, 03-DEC-1987.
FEATURES Location/Qualifiers
source 1..4339
/organism="Saccharomyces cerevisiae"
/mol_type="genomic DNA"
/db_xref="taxon:4932"
CDS 457..3648
/note="multidrug-resistance protein"
/codon_start=1
/protein_id="AAA34849.1"
/translation="MRGLTPKNGVHIETGPDTESSADSSNFSTGFSGKIRKPRSKVSK
ACDNCRKRKIKCNGKFPCASCEIYSCECTFSTRQGGARIKNLHKTSLEGTTVQVKEET
DSSSTSFSNPQRCTDGPCAVEQPTKFFENFKLGGRSSGDNSGSDGKNDDDVNRNGFYE
DDSESQATLTSLQTTLKNLKEMAHLGTHVTSAIESIELQISDLLKRWEPKVRTKELAT
TKFYPNKSIETQLMKNKYCDVVHLTRYAAWSNNKKDQDTSSQPLIDEIFGLYSPFQFL
SLQGIGKCFQNYRSKSKCEIFPRTAKETIYIMLRFFDVCFHHINQGCVSIANPLENYL
QKMNLLPSTPSSISSAGSPNTAHTKSHVALVINHLPQPFVRNITGISNSELLSEMNND
ISMFGILLKMLDMHKNSYKNFLMEITSNPSVAKNTQSIDVLQEFIHYCQAGEALIALC
YSYYNSTLYNYVDFTCDITHLEQLLYFLDLLFWLSEIYGFEKVLNVAVHFVSRVGLSR
WEFYVGLDENFAERRRNLWWKAFYFEKTLASKLGYPSNIDDSKINCLLPKNFRDVGFL
DNRDFIENVHLVRRSEAFDNMCISDLKYYGELAVLQIVSHFSSSVLFNEKFTSIRNTS
KPSVVREKLLFEVLEIFNETEMKYDAIKEQTGKLFDIAFSKDSTELKVSREDKIMASK
FVLFYEHHFCRMVNESDNIVARLCVHRRPSILIENLKIYLHKIYKSWTDMNKILLDFD
NDYSVYRSFAHYSISCIILVSQAFSVAEFIKVNDVVNMIRVFKRFLDIKIFSENETNE
HVFNSQSFKDYTRAFSFLTIVARIMLLAYGESSSTNLDVISKYIDENAPDLKGIIELV
LDTNSCAYRFLLEPVQKSGFHLTVSQMLKNRKFQEPLMSNEDNKQMKHNSGKNLNPDL
PSLKTGISCLLNGIESPQLPFNGRSAPSPVRNNSLPEFAQLPSFRSLSVSDMINPDYA
QPTNGQNNSQVQSNKPINAQQQIPTSVQVPFMNTNEINNNNNKNNINNINNNNSNNFS
ATSFNLGTLDEFVNNGDLEDLYSILWSDVYPDS"
BASE COUNT 1438 a 834 c 787 g 1280 t
ORIGIN 1 bp upstream of XhoI site.
1 ctcgaggata tataattctg cttttccata gtaacgccaa acgatcgcgt aataccggca
61 attacgggat gcacgaaaat agcgccaagg aacgaaaaag aaatgagtct cgtttagtta
121 ttaaacgaga agaaacgagc cctgatttac attctcaggg tccaataggg ctttgttgga
181 aacagacgca taccctaaat ggagtttctt ttcttgttca agacctaatg agtggcaata
241 agaggcgcta attaaagctc ttcaaaacaa ccttattcgc ctattacaca tgatcagcca
301 ctctttcatt gtcaacaata gcatgatagc aggaccatag cggccatata gacattacca
361 ggagtgagtt ttggctaaaa aaagacaatt tgcacatcac ttgctaacta ttcatctcag
421 ccaagaatat acagaaaaga atccaagaaa ctggagatgc gaggcttgac acctaagaac
481 ggtgtacata ttgagacggg tccggataca gaatcgtccg cggactccag caacttttct
541 acaggtttca gcggcaagat tcgtaagcca aggtcgaaag taagtaaagc gtgcgataac
601 tgtagaaaaa gaaagataaa atgtaatggg aagtttccct gcgcaagctg tgagatatat
661 tcatgtgagt gcacgttcag cactagacaa ggtggcgctc gaataaaaaa ccttcacaag
721 acgagtttgg aaggtacaac cgtacaagtc aaagaggaaa cagattccag ttcgacttct
781 ttttctaatc ctcagcgatg tacagacggg ccatgcgcag tggaacaacc aacgaaattt
841 tttgagaatt tcaagctagg tggtcgtagt agtggtgata atagcggaag tgatgggaag
901 aatgacgacg atgtgaatag aaacggtttt tatgaagacg atagcgaatc acaggcaact
961 ttgacatctc tacaaaccac tctgaaaaat ttgaaggaga tggctcattt aggtacacat
1021 gtaacctcag ccatcgagag cattgaactt cagataagtg acttgcttaa gcgatgggaa
1081 cccaaagtga ggaccaaaga attagcaaca acgaaatttt accctaataa atcaatagaa
1141 actcaattga tgaaaaacaa atactgtgat gtggtacatt tgacaagata tgccgcttgg
1201 tcaaacaata agaaggacca agatacttct agtcaacctt tgatcgacga aatctttggt
1261 ttgtactctc ctttccaatt tttgtcactt caaggtattg gtaaatgttt ccaaaattat
1321 agatccaaat ccaaatgcga gatttttccc aggaccgcca aggaaaccat atacatcatg
1381 ttaaggtttt tcgacgtttg ttttcatcac atcaaccaag gctgtgtctc catagctaat
1441 cccctggaaa actacctaca gaaaatgaat cttttacctt caaccccatc ttcgatatca
1501 tctgcaggga gcccgaatac agcacacaca aaatcgcatg ttgcgttagt gataaatcac
1561 ttaccgcagc cctttgtgag aaatataacc ggaataagta attctgagct actaagcgaa
1621 atgaataatg atatcagcat gtttggcatt ttattgaaga tgttggatat gcataaaaat
1681 tcctacaaga acttcctaat ggaaatcaca tctaacccct ccgtggctaa aaacacgcag
1741 tcaattgatg tcttgcagga attcatccat tattgtcaag ctggagaggc gctaatcgcc
1801 ttatgttaca gctattataa ttctacatta tacaactacg tggacttcac atgcgacata
1861 acgcatttag agcaacttct atactttttg gatctgctat tttggctatc ggaaatatac
1921 ggttttgaaa aagtcttgaa cgtagcagtt cattttgttt caagagttgg tttatcaagg
1981 tgggaatttt acgtgggtct tgatgaaaac tttgctgaaa gaagaagaaa tctctggtgg
2041 aaagctttct atttcgagaa aactttagcc tctaaacttg gctatccttc gaacattgat
2101 gactccaaaa tcaattgttt attacctaag aattttcgag atgttgggtt cttggacaat
2161 agagatttta tcgagaacgt ccacttagtt cgcaggagcg aagcttttga caacatgtgc
2221 atatccgact taaaatacta tggcgaatta gctgtcttac aaatagtcag ccatttctca
2281 tcatctgttt tattcaatga aaaattcacg tcaattagga atacatcaaa accatctgtt
2341 gttagagaga aactactctt cgaggtactc gagattttta acgaaacaga aatgaaatat
2401 gatgctatca aagagcaaac tggaaaattg ttcgatatcg cattctctaa agatagtact
2461 gaactcaaag tttcaagaga ggataagatt atggcttcaa aatttgttct attttacgag
2521 caccatttct gcagaatggt taacgaatct gataatattg tcgccagatt atgcgtgcac
2581 agaaggccct caatactaat tgaaaacttg aaaatatacc ttcacaagat ttacaaatca
2641 tggaccgata tgaacaaaat cttattagac tttgacaacg attattccgt ataccgttcg
2701 ttcgcccatt attctatcag ttgcattatt ttggtatcac aagcattctc agtggccgaa
2761 ttcattaaag taaatgacgt tgtgaatatg attagagtct tcaaaagatt tttggatata
2821 aaaatttttt ccgaaaatga gaccaatgag catgtcttca acagccaaag ctttaaagac
2881 tatacaagag ctttttcttt cctgacaatc gtcgctcgta tcatgctttt ggcatacgga
2941 gagtcctcta gcaccaacct cgatgttatc tccaaatata ttgatgagaa tgcgccagat
3001 ttaaaaggta taatagaact tgtcttggat acaaactctt gcgcttatcg atttttatta
3061 gaacctgttc agaagtcagg attccattta acggtctcac aaatgttgaa aaatagaaag
3121 tttcaggaac cactaatgtc aaatgaagat aataagcaga tgaagcataa ttcgggaaaa
3181 aatttgaatc cggatctccc aagtcttaag acgggcattt catgcttact aaatggcatt
3241 gaatcgcctc aattgccatt caatggtcgc tcagcacctt ccccagtgag aaacaactca
3301 ctaccggagt ttgcacaatt gccttcattt aggtcattat ccgtgtctga tatgatcaat
3361 cccgattacg cgcaaccaac aaatgggcaa aataattcgc aagtccaatc taataaacca
3421 atcaatgctc agcagcaaat acccacttca gtacaagtac catttatgaa cacaaatgaa
3481 atcaacaaca acaacaataa aaacaatatt aacaatatta acaacaacaa cagtaacaat
3541 ttttctgcaa ctagttttaa tttggggaca ctagatgaat ttgttaataa cggtgatctt
3601 gaggacctct acagtatcct gtggagcgac gtttatccag atagttaaac gtatacgttt
3661 gtatagataa aagttctcaa aaacttcctt cctttttttt ttcttttgag tttacttatt
3721 taaataagaa cattctgttt tctagggcga tctccttctc ttatttcttc aacactattt
3781 accagtatac cataaagtga aaattcctat tttttttgct ttggatattc atttgatcct
3841 caacgaaaaa aaaaatgatg tattttagta ttgtacaaaa gatattatat gaggctaacg
3901 taaaaaaagc taaactgagg atatatgtat caactatgaa tctaaatgta acattccgat
3961 gattctttta ccatgaggtg tatttcttat ggggcccacc agtaaaggcg ccacaatctc
4021 tgatagtctt ttatagagat agtcattttg cttatgagaa atgtctaatg ctgtctgtaa
4081 aacgtaattt ccgtagctat cattcaacaa tgattgaata cccgtctcgc caccattatt
4141 taaaatttcc agaatcattg gctccgaaac aatagctgtc ttcaagattt tttcaatcac
4201 atttgatcca aatttatgga tagaaagttc gatggctctt ggtttcaaca ggtggacaat
4261 tttatgcgta taatcatatt tgttcttctc agcctctttg gtaattatat attgcaccac
4321 atagttgcca aatggatcc
//