LOCUS D86992 24132 bp DNA linear HUM 27-MAR-2002
DEFINITION Homo sapiens immunoglobulin lambda gene locus DNA, clone:123E1
upstream contig.
ACCESSION D86992
VERSION D86992.1
KEYWORDS immunoglobulin light chain.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 24132)
AUTHORS Shimizu,N.
TITLE Direct Submission
JOURNAL Submitted (08-AUG-1996) to the DDBJ/EMBL/GenBank databases.
Contact:Nobuyoshi Shimizu
Keio University School of Medicine, Department of Molecular
Biology; 35 Shinanomachi, Shinjuku-ku, Tokyo 160, Japan
REFERENCE 2
AUTHORS Kawasaki,K., Minoshima,S., Mine,E., Shibuya,K., Shintani,A.,
Schmeits,J.L., Wang,J. and Shimizu,N.
TITLE One-megabase sequence analysis of the human immunoglobulin lambda
gene locus
JOURNAL Genome Res. 7, 250-261 (1997)
COMMENT
FEATURES Location/Qualifiers
source 1..24132
/chromosome="22"
/clone="123E1, upstream contig"
/clone_lib="specific cosmid library; LL22NC03"
/db_xref="taxon:9606"
/map="22q11.2"
/mol_type="genomic DNA"
/organism="Homo sapiens"
/tissue_type="human/rodent somatic cell hybrid"
misc_feature 1..24132
/note="itv-region III"
CDS join(18391..18436,18523..18914)
/codon_start=1
/db_xref="IMGT/LIGM:D86992"
/gene="VpreB"
/protein_id="BAA19987.1"
/translation="MSWAPVLLMLFVYCTGCGPQPVLHQPPAMSSALGTTIRLTCTLR
NDHDIGVYSVYWYQQRPGHPPRFLLRYFSQSDKSQGPQVPPRFSGSKDVARNRGYLSI
SELQPEDEAMYYCAMGARSSEKEEREREWEEEMEPTAARTRVP"
exon 18391..18436
/number=1
exon 18523..18914
/number=2
BASE COUNT 6219 a 5791 c 5738 g 6384 t
ORIGIN
1 gatcaatcac cccaaacagt ccagtgaccc ctgatggttg agcagcagca ctagaacccc
61 aaatttctag gggagaccca gcttccagtt tattaagttc catgcactta attcttgttc
121 tgcttgattt tgggtcagca gttacatgaa ctcacgtgtt tctcaaccag tgttctggag
181 atctggctca gtgcagggct gtggtttcaa agttattcaa gcaatgccac caaaagcctg
241 taccccagaa tacctgccat aggccatcct gtctatccct ggagacagtc ccttcttatt
301 gaagatgaag cactttggcc cgtagctggt tgccagagct ttcagaaaag cgtcggagta
361 aaacaaccat ctctgatgac aaaagactta aaatggctgt gaagagctct attaattcct
421 caaatattca ttgctctatt ttttatctcc ttttataact cctactgcca ggctattggc
481 ctttctactt ctatcctctc cccgacattc ccatcttagt aaatgactcc acaagtactt
541 cagctcccat tcaaggacct tggattaccc ttgggtcctc tctcttactc aacagcccat
601 cctatgccaa gtctcaccaa ttcttctctc tctctacaca cacacatata caaacttatt
661 tgtaaacaat tattttaaaa aatctctctt ctgaggttcc agctttcttc ttcttttatt
721 tttttgagac tgagtctcgc tttgtcaccc aggctggaat gcagtgacac gatcttggct
781 cactgcaatc tctgcctcct ggtttcaagt gattctcatg cctcagcctc ctgaggagct
841 gggactacag gcatgcatca ccacgcccag ctaatttttt tgtattttta gtaaagacag
901 gatttcacta tgttggcctg gctggtctca aactcctgac ctcagataat ctgcccacct
961 tggcctccaa agtgctagta ttacacgatg agccactgtc cccagcctct ctctcttttt
1021 tttttttttt tttttttgag acagggtctt actctgtcgc ccaggctaga gtgcagtggt
1081 atgatcttgg cttactgcag ccatgatctc ccaggctcag gccatcccac ctcagcctcc
1141 tgactagctg ggaccacagg catgctccac catgcccagc taatttgtgt attttttttg
1201 tagatacagg gtttcactat gttgcccagg ctggtgtcag gctcctaggc tccagtgata
1261 cccccacctc ggcatcccaa agtactggga ttacaggggt gagccaccac acccagtcac
1321 agctttcttt ttagagttca ccacagtttg agtgattatt tggaattttt aagtggcaaa
1381 aattacaaca atatatttgt aaatgaaaga gaattgtgaa atgtatttga aattttaact
1441 ttaagatttt ctttaaaata cccatattga atgaagagta tcaaagtaac tattgcttaa
1501 aaaatggggc ttcatttggg ttaaaacaca agaatcatga acatgatcaa aattcttcaa
1561 agtgcttgct tggaatgata cagagaggat tagcaaatac aaatagtttt tttttgtttg
1621 tttgtttttt tttttttttt tttttttttt ttttttaaga gatgcggtct cactatgttg
1681 ctcaggctgg tttcaaactc ctgagctaaa gcaatcctcc tgtcttggcc tccccaagtg
1741 ctaggattac aggcattgag tcaccactgc tggccaagat gctgatcttt ttgttgttgt
1801 tgttgttgcc taggctggag tgcagtggcc tgatctcagc tcaccacaac ctccgcctcc
1861 cagattcaag caattctcct gcctcagcct cctaagtagc tgggattaca ggcatgcgcc
1921 accacgcccg gctacttttt gtgtatttag tagagagggg tttctccatg ttgcccaggt
1981 tggtcttgaa ctcctgacct caggtgatcc acctgcctca ggctcccaaa gtgctggtat
2041 tacaggcatg agccaccgcg cccagtgatg ctaatcttat gaaagacaac caacaacaaa
2101 ttctgaatac taaagtgtgc gaaatgtatt taattctttt catagcacag atgagttaac
2161 ccacgatgtg ttgtcccagg cactatggag tcatcttgaa tttcatgttc taaacaaaca
2221 cccttggcct ggaggaatgc acctgcatat cacgacagga cctagtgtct cagatttagt
2281 ccggcagctt tgaatttgga aatcctcttt ggagcttctt ctgacacagc atcttttctc
2341 tctgggaagg taggtgacac ctgagaacag aggcatggtg tggcatcaga gatggaggta
2401 agaattattt ttctaccaca atcccaggaa aagactctcc tgttcctggt gagggtgaga
2461 gctctggctg aggatgtcct ctttcttctt tcttctccag aggatttttc agtctctctg
2521 caaatggctg cttcacagcc agggttcatc gaaacccctg gatcgtcatg gccagtggtt
2581 tgcgtctctc cagcgccact ccatacgagg gtctttctgc atcctgctct catggtggac
2641 ttctgagggc catgctcctc atttgcaggg ctcacaaata ttctgtaaat atccaccagt
2701 gttctgataa cggggtgacc caggacaaac tgaccgtctc cagggttcag gtcccaggca
2761 tgtctagctc cctctttcct ttcactgaaa actaatgtcc tgtttttttc cgtatctata
2821 tggacctttc tgggttcagt ggtgtgggaa aaatagattg ttggtgaaga ctcatcttca
2881 tctcctgaac tgccatcatt gcagtgttca gagtggggat ggtgcttgga atcattccct
2941 tgaccttgcc ttcgaccttg cattagtttt gactttaaaa tgtccttatg aaaattcccc
3001 caagtacgga agcccatagt ctcatcagag atcccacctt ttccctgttc ccctccattt
3061 ttttttcttt tttgaaatgg agtctcactc tgttgcccag gctggagtgc agtggcgtga
3121 tctcggctca ctgcaacctc cacctcccag gttcaagcga ttctcctgcc tcagcctccc
3181 gagtagctgg gactacaggt gcccgccacc atgcccggcc aatttttttt atttttagta
3241 gagacggggt ttcaccatat tggccaggct ggtctcgaaa ttctgatgtt gtgatctgtc
3301 tgccttggcc tcccaaagtg ttgggattac aggcatgagg cactgcaccc agccccttcc
3361 cctctgtttg tgaactccat cccaggatca tggttgagtt cacccagcag gttttcttgc
3421 ctctccagtt cttccagtcg agcccacagt tcctcatttg taagtaagca tccttggact
3481 tgagatcatt ttcaaaacct gaggttttgg attttgaatc aggtttatgt gcaatccagg
3541 gttttctctt taattcagac ttgttttgaa catgttttct taggtcaaca agatctccat
3601 ccccatcacc ccatccctgc agatctgctg tgaatgcaac tttagattca aagtttctcc
3661 tggcttttgt aaagtcatgt agtgctttcc tcacacactc cttcctatgc tccactaacc
3721 ccactgcttg ctttgcagag cactggcaaa accagttgtc cccgaggaga agagtgattt
3781 tgctggtatc cacaagcctt cctggtatag aaggcaagag gcccagttgg caccatgagc
3841 tcgtaagaca gcctattggg caaggtttgg agtcgctctt ggagggtatt acagtccccc
3901 tttacctttt gccagtgtgc aatttcatct tggcacctag agatcatctt ttcctgttct
3961 ccttggggcc tcataacctg ttgaggatgc agctgtttga aggtggccga ggaggctgca
4021 cggtggggca cacggtgggg ctccatggct cctggttctg cgtgtgcgct gtggtcggca
4081 ctgctcaggc tgctgccccc agtcatggcg actgcagtgc ccaacttcct ccagctgagt
4141 cctcatgaga tccttcctgc aatcagtgct cccagctcct cagtcccttc aaaagataaa
4201 tcattccgga gatgggcggt ggtgatgtag catgacaatg tggctacttt caatgctacc
4261 gaactgcata ccaaaaaatg gttaaaatgc tgaattttat gttatgtata ttttaccaca
4321 ttaaaaaaat attagctggg tacagtggct cacacttgta gtcccagcac tttgggaggc
4381 tgaggcagga ggattgcttt tagtccaggc atttgagatc agcctgggca acacagtgaa
4441 acccccatct ctacaaaaaa actcacaaaa ttagctggcc aagttgattg tgtgcctgta
4501 atctcagcat ctctggaggt ggaggtcggg ggattgcttg agcccaggag ttcaaggcct
4561 cagtgtactg taatcacacc actgcactcc agcctgggtg gcagagcgag atccagtctc
4621 caaaataata atagtaataa ataatagtaa taataataaa taaataagtg ataataaata
4681 aaaatatcca cttgggataa ttatcacaag aactttgctg tcatggttgt gattttttgg
4741 aacaaattct catggttcta actaaaccaa atcaaataca acattgattt gaacgcccat
4801 gctcacagca gccttattca caaaaaccac aaggtagaag caacccaaat gtccatcgac
4861 agatgaatgg atcaacaaga tgtggtctct ccacacaatt cagccttaaa aaggaaggaa
4921 attccaacac atgcgacaac atgcaggaac tttgaagact ttatatatac taagggtacc
4981 caccccctac ctcactgtat tcatatgttg aaatctcaac ccccaagctg atggtattag
5041 ggtatgggat tattagattc aaagtttggg acataattag gtcatgaggg tggagctccc
5101 atgatgggag ttgtgacctt ataaaaggga ttccagaggc ccctcttacc ccttctgcca
5161 cgtaacaata caacaggaag tcagaagtct gtgaatgaaa gagggccctc accagaaccc
5221 aaccatgcta gcccttcatc ttggacttcc agcctccaga gccatgaggt atcaatgtct
5281 gttgtttata aaccacccag accatggtac tctgttatgg cagcccgacc tcactaagac
5341 actaatcaaa acaaaccggt ccacaaaagg acaaacactg tatgattcca cttacatgag
5401 gtacctagag tagtcaaatt cctacagaca gagtagaatg gtggtttcca ggggctgagg
5461 ggagagggaa atggagagtt gtttaatggc atggagtttt agttttgcca aataaaaaag
5521 ttctggatta gttggacaac aatgtgaatg tacttcatgc ttctgagctg tacacttaaa
5581 aacggttgcc tgggcatggt ggctcatgcc tgtaatccta gcacattggg aggccagggc
5641 agaggactgc ttgagccgag gagttcaaga ccagcctggg caacatagca agactctgtc
5701 tctacaaaac atttttaaaa aaattcacca ggtgtggtgg tgcacacctg tagtcccagc
5761 tacttgggag tctcaggtgg gaggactgct tgagtctgga tgttcgaggc tgcagtgagc
5821 tgtgatcaca ccactgcact ccagcctggg caacacatag tgaagccgta tctttaaaaa
5881 aaacaatggt gagactgggt gcgttggctc acacctataa tcccagcacc atgggaggct
5941 gaggtgggtg gattgtttga gcccaggagt ttgagaccag cctgggcaat gtagcaagac
6001 cctgtctcca caaaaagtta gctgggcatg atggtgcatg tctgtggtcc cagctacttg
6061 ggaggctgag gtgaaaggat tacttgagcc taaaagattg aggctgcagt gagctgtgat
6121 tatgccacta tactccagcc taggtggcag agtgagacct tgtctcaaaa aaaaaaaaaa
6181 atggataagg tggtaagttt tatgttatgt gtattttatg ttttttttat tttttaaaga
6241 aacagggtct tgctatgttg cccaggctag agtgcaatgg ctattcacat gtgtgatcag
6301 agtgtactac agcttccaac tcctcagctg gagttgaggt gattctgcct cagcctcccg
6361 agtagctgag accacaggtg tgcacagctt tgcctggctc cattttacta cactacagtg
6421 tctctctttt tacatggttg ttgcagtaaa agaaaattca gtgtatatag aaacatcaca
6481 agcaattgtt ttaagattat atgtaaagtg gaaataagtt gtagactcat atagttgtca
6541 ataggttttc taacataaga actttgggtg gggcacttga gaactgattc agatggaaga
6601 tggctctagg ctggtggaac agtgttgaga attcctgaat gtgtagtatt cctagacctc
6661 tgtccaccaa attaaagcag gtcccccatc accatgatcc tacagggggc atccccctta
6721 gtaacccatg gaatctggcc cggcctcttt ctctagccta aattgagaca ttctcctcct
6781 tgtttctcta ggcctcagcc acactggcct tcttctattt ccaaacacac accaagctct
6841 ctcctgaaac acagccttcc cacacaccgc atctctgcct agttcataca ctgccggcaa
6901 attgtgtatt ggggctgggc ccttcccact gttcagctgt catcctattt ttttcctttg
6961 tcaggggtcc tttgaaaact acgtattcca gaccaggtgc ctggacattc tctcttatga
7021 cacttattaa aacatgttgt tggctgggtg cggtggctca cgcctgtaat cccagcactt
7081 tgggaggccg aggcaggtgg attgcctgag ctcaggagtt tgagaccagc tgggcaacat
7141 ggtgaaaccc cgtctctatt aaaatataaa aaatcagccg ggcatggcag tgtgtgcctg
7201 tagtcccagc tactcgggag gctgaggcag gagaattgct tgaacctggg aggcggaggt
7261 tgcagtgagc tgagattgca ccactgcact gaagcctggg agactctgtc tccaaaaaaa
7321 acaacaacaa aaccaaacaa aaccaaaaca aaagaataaa aaaaaatgtt gttgtcatta
7381 ttttcccgct agactcccac aagattcccc actagactct aagcttcatg ggaggagggg
7441 ctatgcacat tcacagtgtc tgctcttacc agagagtctc acagagcagc cctaacaggt
7501 tagaccaaag aacaggtcat ataaaaaccc aagttccaat ttctcctgag atgtttttct
7561 cctaaaaacc aagttaagaa ctctaggcct ctactgggaa gctgcctccc cattcagaca
7621 gggtctcccc attaccacaa tcccttctag tcctctcttc tacttgcctc cctaggtgat
7681 cattgcaggc atctgagttt gtaaacccga gtttacaaaa ggggattaga gaaatgccca
7741 catcaaatga tctcattcac ccatttctca gattctaggt cctgatggtt ggcacatgtt
7801 gcaatgagtt ggatgggggg agtccagcca ggacctcagg gtagccacag acttcttcaa
7861 tttccaccct ctaaggtttg gtcctcagat tggaattatg tttcctcaat tctctgcaga
7921 caggaagtgt tgagatctga ctcttagtag taatttaaat gagagaaaga gaggaggagg
7981 gaggtatttt tatatcctat ttgtatctaa ataccagaaa aggtagggag tgggggctta
8041 cacctgtaat cccgacactt tgggaggcca agacgggaga atctcttgag cccaagagtt
8101 tgagaatagc ttgggcaacg tggcatgacc ctatctctac aaaaaataca aaaattagtt
8161 ggacatggtg gcatgtggct gtagtcccag ctatttggga ggctgacatg ggaggattgt
8221 tttagcctag gaggtcaagg ctgcagttaa ctgtgattgt accactgcac tccagcctgg
8281 gcgacagagc aagactgtct caaaacaaac aaacaaataa acaaacaaac agaaaaacaa
8341 acaacccggg aaaatggtac tttgggaaca aggaccttgg tcaacccaat tccttattga
8401 aggaaataac gtatacagtg gtccatttct tttttttttt tttttgagac ggagtctttc
8461 tctgtcgcca ggcttgagtg ctgtggcgtg atctcggctc actgcaacca ccgactccct
8521 ggttcaagcg attctcctgc ctcagcctcc caagtagctg ggattacagg catgcaccac
8581 catgcccaga acatttttgt atttttagta gagatggggt ttcacaatgc tggccaggat
8641 ggtctcaaac tcctgacctc gtgattcacc tgcctcgacc tcccaaagtg cgtgctggga
8701 ttacaggtgt gagccactgc acccagccta cagtggtccg tttctaagac aaaatgcttt
8761 gaattggctt aggtcagcaa cctacagaag aaacatgata cactaggtcc ctgcttggat
8821 agccagccaa tgcctgcttg tcagcctccc ccttccccac cttcgcccct tagttgcctt
8881 cacctgaacc aaagtagttt agtctaagat gaaagtttac tagcctgcaa aatagcttgt
8941 tttgtctgtt cttagcctgc ccagctactt aggtcataag tctaacactt gaagagcccc
9001 taagctaact aagattacaa tgcattgtgg gctgcaacaa aatgcagcaa aacgacccta
9061 aaataaacaa aaaacaaaaa actcctggcg ctcccaccca acaatcaaca ggcgagaagt
9121 ttatgacccc gtagtactca gcctatgagg aactggggga gggacctgtg cactagggga
9181 taaactgctt gttgaaagtg tgctgggtgt gcctgtcaga cacctgatct tgcaagactg
9241 tcattaaaag tctcactttc actgttctcc gggtctccga gtccattctt tgggttggga
9301 tgggcgagac tgtttctcac attatgaaaa gctgaaggtt aagtgaactt ggggaatact
9361 gcctcctgct ggctggatgt catggaagcc tggcccatca gcagagaatg ataagctgga
9421 gttctggagg gtctgatttc caaggaatca cccccttgga agctcctcta atacaccctg
9481 atgagattaa cctgattagg tccattgttt gataaaaaga ggaggaagtt taatcacttc
9541 cacattcttt gcccacgact aaccctgatt ggatttgggg ctatggttca aatgtatgac
9601 cgattgattt ttttcacttc ttctgttgga cttttgaaaa aaagttctct gaaaaggaat
9661 ttagaggaaa gagacttatt ccagtgaaca gttacagttt gcaaacccaa cagacacaac
9721 ttttggtaca aaaggaagtt acattccaga gaacaagggg aggctttgtc ttttctagag
9781 aaaattcccg ctcagaatcc cactcaggtc tgcttatgca aatgaaagat tcaaactttt
9841 tagttctgat tacttggctc tagctgggtt ctgattagtc aaagcaggtc acagtctact
9901 ggtggcgtaa acaggaacag gcagctatgt aagtcccaaa gtttttccag aaactcaaag
9961 tatgtgtgtg acctctggtc agcaaataac cacttgtctc aaatttaaat tcaggcccag
10021 gattcatctt gaggaattgg ctctttcagg gttcagagac caatcaaaat gtctatcaga
10081 atggatgtgt taaaaggcaa ataatgggca gggcatggtg gctcaagcct gtaatcccag
10141 tactttggga ggccgaggca ggtggatcac ctgagctcag gagttcgaga ccagcctcgc
10201 caacgtgatg aaaccccgtc tctactaaaa atacaaaaaa aattagctgg gcgtggtggt
10261 gtgcgcctgt aatcccagct acttgggaag ctgaggcaga agaatctctt gaaccctggg
10321 ggcggaggtt gcagtgagcc aagatcatgc cactgcactc cagcctgggt gataagagca
10381 agactctgtc taaaaaaaaa aaaaacagca aataacgttg tcctgtgcca tgagccacat
10441 actcaaatat ttacacaggt ccaggggaag taaagagtaa atatggccac caggcgcggt
10501 ggctcacgcc tgtaatccca gcactttggc ggctgaggcg ggtggatcac gaggtcagga
10561 gatcgagacc atcctggcta acacggtgaa accccgtctc tactaaaaaa tacaaaaaaa
10621 ttagccaggc gtggtggcgg gcacctgtag tcccagctac ttgggaagct gaggcaggag
10681 aatggtgtga acccgggagg cggagcttgc agtgagccga gataatgcca ctgcactcta
10741 gcctgggcga cagggtgaga ctgtctcaaa aaaaaaaaaa aaagagtaaa tatggcctga
10801 tgtgaaaaaa aattataacc accagaattt cctaaaatgt attttattga tctatagtgt
10861 tattgcacaa catccacaaa tatctatgat gacaattgtt taaaattcaa gttaaaatac
10921 aaaatttaaa aaagtttacc tacttttacg ttgttaattt atgactcttt gggtttgaaa
10981 tgagatttga tgtcattgta tttatagata ttccttgact tcttgtgtta tgtaccaata
11041 agcacattgt taagttgaaa acatcataaa taaaaaatgt gtagctgggc caggagctat
11101 ggctcatgcc tataatccca acactttggg atgccgaggc aggaggatca cttgagctca
11161 agagttcaag accagcctgg gcgacaaagc aagaccccca tctccacaaa aaattaaaaa
11221 attagccagt tgtggtgctg catgcctggg gtcccagcta cttgggaggc tgaggcagga
11281 ggatcatttg aacccaggat gtcgaggctg aagtgagcta tgacggtgtc actatgctcc
11341 agtctgggta acataatgag accttatttt taaaagaaca cacaatgagt agctgagtag
11401 ggctgcggct cactgccact gccagtgttt gaagaacagt tcccactgaa tgcatctcaa
11461 ttttgcactg taatcaagta gaaaaactgt aagtccaatc attgtaagtc tgggaccatc
11521 ttgtccatag tcttatgaca gaatactgtt taaaagtgta gatctatccg aatgttgatg
11581 aatttattgt gaaatgcttc cccttgtgtt gcttctatgt gatctatgtg cagcagtgga
11641 catttttttt ttaagtgaaa aacaaatcat gcccctccct tcattctctc ccccgtgatg
11701 tttcccttag agaacattcc tcccttccct tcccagtccc cacctcagag atggggcaac
11761 tcctcccttt ttatcacact tcttccactc tgaggctcta ggcaatcagt tctcggtcac
11821 tcccacccat gtgaaggttt tttttttttt tttttttttt gagttggagt ctcgctctgt
11881 cgcctaggct ggagtgcagt ggtgcaatct cggctcactg caagctccgc ctcccgggtt
11941 cacgccattc tcctgcctca gcctcccgag tagctaggac tacaggcacc tgccaccacg
12001 cctggctaat ttttttgtat ttttagtaga gatggggttt caccatgtta gccaggatgg
12061 tctcgatctc ctgacctcgt gatccgcctg ccttggcctc ccaaagtgct gggattatag
12121 gcgtgagcca tcgcgcctgg ccccgtatga aggtttttga tgatgcttgc tagaatggac
12181 ccagataatt ttcgtgtgga cagaaggtag atttttagta gctcttgtta gaggtcatgt
12241 aggagattgt ctcagcttga gctgctattg caaataccga tactgtagac tgggtggctt
12301 gaaaacacca gaaatgcatt cctcagagtt gtggaggctg gatgtccaag ataggacagg
12361 tctgagatca gggtgccagc atgcttcagt tctggtagga atcctcttcc aggctacaga
12421 ctgccaactt ctcgtgtctt cgtgtggcag aaaaagggct aaaaagatct ctgggatttt
12481 tttttttttt ttttgagaca gagtctcact ctgttgccca ggctggagtg tagtggtgtg
12541 agtggcatga tcttggtata ctgcagtctc cacctcccgg gttcaggcaa ttttcgtgtc
12601 tcagcctccc gagtagctgg gactataggc gtgtgtgacc atgcccgact aattttggta
12661 tttttagtag agactgggtt tcaccatgtt tgccaggctg gtcttgaact cttggcctga
12721 agtcatgtgt ctgccttggc ctcccaaagt gctggggttg caggcacgag ccaccgtgcc
12781 cagcagggcc tcttttgtaa aggcactaat cccattcgtg aggttctgcc ctcatgacct
12841 aattacctcc tacaggtccc atgtctgagc accatcacac tggcatttag gatttcagct
12901 tatgaatttt gggaggacac aaacattcag ttcataacag cattgtgttg tcacccactt
12961 tttttttttt ggtaggaaca gtgtgtcgaa ctctggtctc aagtgatcct gctgcgtcag
13021 cctcccaaag ctttgggatt acaggcacgc actgccaagg ccagccacat ccatattctt
13081 aatctccacc atggcctcat gagcctggtc ccctgtcagt gggctagggc ctcgacatgg
13141 gtaatacgca tattagctga ggttcaggaa cccaactgac ttgtgtaaga atttccagct
13201 ggccccgcag aacaagaggc taaagagtgg ggagcagtgc tagtgttgcc actgctacag
13261 ctctcgggca gtattcacta ccctcatcct gtatgtgtgc ccaggtgctg ggtgagcatt
13321 tcactccaca cgagaggcat catgcattcc ttcattcgtt cgttcatgcc gttatactat
13381 agtgaacaat aaactcttga ggaatgtcgg gtttagggga gccagtcccc tgttcagttg
13441 aaaatctgcc tggctatgta taaattttga ctcccccaaa acttaactac taatagcctg
13501 ctgttgactc gaagccttac tgatgatatc aacagtcaat taacacatac tttgaatttt
13561 atacgtatta tgtactgtat gcattttttt ttctttgaga tggagtctca ctttgtggcc
13621 ctggttggag tgcagtggca ccatctctgc tcactgcaac ctcccagatt taagtgattc
13681 tcctgcctca gcctcccaag tagctgggat tacaggcatg tgccaccaag cctggttaat
13741 ttttgtattt ttagtagaga tggggtttca ccatgttggc caggctagtc tcaaactcct
13801 gacctcaagt gatccacctg cttcggcctc ccaaagtgct gggattacag gcgtgagcca
13861 ctgcaccctt cctgtactgt attcttataa taaagtaagc tagagaaaag aaaacgttat
13921 taagataatc ttaaggaaga taaaatctat ttactattca ttaggtagaa acagatggat
13981 tatcctacag gaggaggagg aagaggaggg ggttggtttt acagtctcag gggcgaaaga
14041 ggcataagaa aatctgcaaa taagtggacc cacgaagttc aaattcctgt tgttcacagt
14101 tagtggtaca caggagacac taggtaagct aaaggttggg ctgggcatgg tggctcacac
14161 ctgtaatctc agcactgtgg gaggtcaagg cgggaggatc gcttgaggcc aggagtttga
14221 gaccagcctg gccaacatgg tgaaatgctg tctctactaa aaatacaaaa agtagctggg
14281 cattgtggca tgtgcctgta atcccagcta cttgggaggc tgaggcacaa gaatcacttg
14341 aacctggaag gcagaggttg cagtgagcca aaatagtgcc acttcactcc agcctgggtg
14401 acagagtgag actgtctcaa aaaaaaacaa acaaaccaaa aagattagct aaaggttgaa
14461 ctttcagtga tgaactaaac agaaacaatc tcatagagat tgtggacagg agaagaaaca
14521 agcacaggtg cagttaaaac ccgtgataaa tgccccggca gaaacaagtg ttaggccagg
14581 cgtgatggct catgtctgta atcccaacac tgtgggaggc caagacagga ggactgcttg
14641 aggccggggg tttcaagcct gcagtgagct atgattacac cactgctctc ctgcctgggc
14701 ggtagagacc ctgcttaagg aaaaaaaaaa gaaaggctgg gcgccgtggc tcacgcctgt
14761 aatcccagca ctttgggagg ccgaggtggg cggattacga ggtcaggaga tcgagacgat
14821 cctggctaac acagtgaaac cccgtctcta ctaaaaatac aaaaaaaatt agcagggcgc
14881 ggtggcaggc gcctgtagtc ccagctactc gggaggctga agcaggagaa tggcgtgaac
14941 ttgggaggtg gagcttgcag tgagctgaga ttgcgccact gcactccagc ctcggcgaca
15001 gagcaagact ctgtctcaaa aaacgaacaa acaaaaaaac aaaacaaaac aaaacaaaaa
15061 cctaaaccaa aaccaaaacg cagcatagtc catgagagag gaagagcagg gcaggcctac
15121 tcacctgggg ctgtcgggga ggctgcccag gaagggactc tgaagtgagc acctggagga
15181 aggaggttag ttctgaggga ctggaattca tcctggcatt gggatcacgg gcaaaggtcc
15241 tgtggtgaca aggagactgg tgcgagcctg gcttagcacc atgtgagagc agaggggtgg
15301 aaaggcacta ggtaagcatg ccttcggatg tgaaatgagg gagacgggga ctgggggacc
15361 ctgacatgag ggaggaggaa aggagatggg aagaatgggt gaccagaggg accactagac
15421 caccgagggt gagagcttgc taatatcaga gccatgtgta ggagaatgaa gtgcaatctt
15481 ggatagacct ccagtgcagg tggtccagcc atcaatgacc ataaccacat gcatgattgt
15541 aggtggaacc agaagaacca cccaggcaac tcacagaact ggggaactaa tcaagtcttg
15601 ttttaaatga ctacattacg ggtggtttgc cacgtagcag tggatcgctg aaacagttta
15661 aaatatctat tcagccgggc gtgcggtggg tagctcacac ctgtaatccc agcattttag
15721 gaagctgagg caggaggatc tctcgaacgc aggaatttga gaccagcctt gagcaaaatg
15781 gcaagaccct gtctccacaa aaagtaaaaa aaattagctg ggtgtggtag catgtgcttg
15841 tagtcccagc tacttgggag gctgggacag gagaattgtt tgagcccagg agttcggagg
15901 ctgcagtgag ctgtgactgc accgctacac tccagcctgg acaacagagt gaaaccttgt
15961 ctctaaaaaa aaaaaaaaaa tctacaaacc aggcaggagc actgaatagc tcctgtctcc
16021 cctgagaccc ttgtagacct tgaggtctgt tacagagctc accaaccttc tcttggtcta
16081 gaattatcta aaaagagttg agtgcagcca gaaaggactg aatacatggt gttcttcaat
16141 cccatcaaac tgctgtgccc tgcagatgat ccctgagtcc aggtgttggt gggttgagga
16201 caaggctgag ggaacagagg tgggaacagt ggcccaggac caggagaatg cagagttcag
16261 agtgcatgac ctgcatctaa ctctagatgc tccaggggtc tgagaccatc tccagcaggg
16321 tctggaaggc ccagtcattc cccagcacgc acagtcacca ctggatacta tcttgctctg
16381 tgagtgatgc aaaggtcctg ggtcagtgaa gcctgtgaaa caaagttggg accagagtgt
16441 ctctacggtt gagggctggg cttatttgct ctctaagtat aattgtaaga gcaaatagaa
16501 acacctatcc tctctgagct taaaaggatc aaaaagctct gacagtgtca gtggtagggc
16561 tagttcaggg gctgcagtag tgctggtgcc cacaggtgga accttctcct gccctgattc
16621 ccaaggactg gtgctctcgg aggggtctgg gaggtatatt tctctttcac aaatacgtgc
16681 acaacacatg aatgagctac tggatgaggg aataaatgaa tgaatgagtg aaaaaagctt
16741 cctttctcct ctccaggagt tagcaatcac tggttagttc cccactgccc accagcctgt
16801 gcagaggagg gaggagcaac aggtcataga tgtggttgca gctgttactg gacagagtgg
16861 tcaagacatc ctgtgtctgc agaggccctc cccagccctc acctggacag tggagctgtt
16921 ggccagagag gcagtgggaa gaagggtggg gctcccagag tcgacccagc gggctgaaac
16981 tggtgcagtc tgcgcctcac caggcagaga atggatgtgg ggcagcttga caccgagcag
17041 gggctcatct gagcctcagg ggtggttgct ctatcaaagt gtttgcaagt aaacagtccc
17101 agtgcacacc cagctgctca gtgccacctc gtgcacccag ggccacttca gccttgatca
17161 caggcctgca caggttccag gggaggagac actccagctt tttgagggag ggtgagcatg
17221 tgggatcaga gactttaagt ccaaatttcc ccttaatttt tttttaaatc ttgcaggtag
17281 tatgcaaaca tacatttaat gtattatttt tattctcatt tatttttttg aggcagggtc
17341 tccctctgtt ggccaggctg gagggcagtg gcgagatctt ggcttgctgc agcctcaact
17401 caacctccca agctcaagtg attttcccac ctcagcctcc caagtagttg ggactgcagg
17461 tgcctgtccg ccatgaccag ctaattttta aatttttttt gtagagatgg ggttttgcca
17521 tgttgctcag gctagactcg aactcctgag ctcaagtgat cctcccacct tggcctccca
17581 aagtgctggg attataggtg tgagacactg catccggctc ccaaatttcc cctttttata
17641 aggacaccag ttgtactgac cggggcccca cctctatgac ctcatctaac cttcattaac
17701 tccttaaagg ccctatctcc aaatacaggc acactggggg ttagggcttc aacctatgga
17761 tttgggggat gcaattcagt ctatcacagt gccaagctgc acctgctcgg tgagccagaa
17821 caggggtggg gaaggcacca ggccctggtg cttctttccc atgcctgagt cactctactt
17881 ggttctagga gggagaggag catgggctga aggcagtgct gcaacatgga aggggcagaa
17941 catcccaacc cgctctgggc ccccagtgtc ttctgctgta caaagcaggt gttttcaccc
18001 cccgaggatg tgtcctccct tcctggctca ccaagcattt aaatgtagac agaaaattta
18061 tttatctggg gtgcggtttc ctcaggggga agttgaggtc acgacccctg aggtacctta
18121 acccaaaggc ctccagggca ctggccccag agtctccagc aggtgcttcc tccctgaatg
18181 cttccatatg gcaagatcag agccacaaat gctgccccga cactgttccg gtaaccgacg
18241 ttgcagaccc aagaaagtct gggatggtag tggccaggaa cggggtgtgc cacggcccca
18301 cctctcagag cagggaggag gatgctgggc cagcccttgg ggaccccagg caccgtggcc
18361 acaggagtca gagctctgca tgtctgcacc atgtcctggg ctcctgtcct gctcatgctg
18421 tttgtctact gcacaggtga gggaaccccc agatcccaaa gactcctgcc ccttccttca
18481 tcctgccctg cccccacggc ccacatgcat ctgtgtcacc aggttgtggt cctcagccgg
18541 tgctgcatca gccgccggcc atgtcctcgg cccttggaac cacaatccgc ctcacctgca
18601 ccctgaggaa cgaccatgac atcggtgtgt acagcgtcta ctggtaccag cagaggccgg
18661 gccaccctcc caggttcctg ctgagatatt tctcacaatc agacaagagc cagggccccc
18721 aggtcccccc tcgcttctct ggatccaaag atgtggccag gaacaggggg tatttgagca
18781 tctctgagct gcagcctgag gacgaggcta tgtattactg tgctatgggg gcccgcagct
18841 cggagaagga ggagagggag agggagtggg aggaagaaat ggaacccact gcagccagga
18901 cacgtgtccc ttgaactgaa gacagcagag gcacgcatcc ccttggagag actgtcatgg
18961 aagagggtgg agccgccgcc cgaagcgccg aggaggctga gccactcagc atctcctggt
19021 cctgcagtgt tgctgtaaat ccccattgga gactgcatta gggaattaaa gctgcttgtc
19081 actttttgct gagtttggtc tgactgttgt gcgacttcgt agtaccagcc ttgggcaaag
19141 gcccggggcc ccgggagact ggcagatcac tgtggtgagc actcacctga gtccttactt
19201 ttgtgggcca tgggaggcaa ggggttgacc gaagcaccct ggaggggcat ccatgcccag
19261 gacaggaccc tctggtgtca tctgattctg cccagcggtt acagggcaaa caagcttaga
19321 aagcacctgg tctgggcctc cagggagaac aggagccagg taataggcct agagtgggtt
19381 ctccaccttg gtcctatcga cgttttgggc tggacagttc ttggttgtgg ggctgtcctg
19441 cggattgttg aatggtgagt ggttatctgt ggcctctacc caccagatgc cccttcccag
19501 ttgtgacaaa caaaaatgtc tccagacatt gccaaatgtc cccaggtggt aaactcacac
19561 tgattgtgaa ccactggtct agatgagcaa gtaaatgcat ttacttattt gtacaagaga
19621 gtggcaggtg tcggcaaaca tgttcttttt ttcctttttt tagggataaa gtcttgctct
19681 gtggtccagg ctggagtgca gtggtgcaat catagctcac cgcagcttca aactcccagg
19741 ctcaagtgat tgtcctgtct cagcctcctg agcagctgag actacaggcg tgcatcacca
19801 tgcttggcta tttatttagt tttatttttg gagagatgaa tgtctcacta tgttgctcaa
19861 gctgatctca aactcctgag ctcgagtgat ccccctgctt gggcctccta aagtgctggg
19921 attagaggcg tgagccactg cacccagccc attttctata aagagccagg tggtaaatat
19981 ttttggcttt gtgggctatg cgatctctgt cacaactgtt caattctgtc ctagtagcaa
20041 gaaagcagcc acagacaaac atgtcaacaa agaggcgtgg ctgtgttctt ataaagctgt
20101 atttacagaa acagatgggg ctacactggg ctgggtatgg cgcccaggct gtagtttgct
20161 gagccctgct cgggagcact ccagctcctg tctccaggtt ttaagcaagc catgcttggt
20221 gggataatca gagtcccccc tcaacttatc ttgcctgtga ccccaggcag aagcctctgg
20281 acccatggag atacctagag gcatgaagga cgtggtctca ctgagactgt gttggactgt
20341 ctgggtgaag tagcaatggg gagctccctg cagccccggc ccacagcaag gccccctgag
20401 cccgtgggtg gtgggtctga gtgtgccttg cagagaggga ctctctacac tgggtgtcca
20461 cacaacctgt agacatgcct cactcagaga ggtgccgggc aaaccatctc ccttgtaacc
20521 ccaacttgcc tgggaacgtg cattcacccc agctaaaaag atcctgaggc atctccccag
20581 agaggtggac acatgtcagt atcagcgttc catgtgtggt catgagtccc tctcttgtta
20641 aacagtggtc tccagcactt tgggaggccg aggcgggtgg atcacctgag gtcaggagtt
20701 agagaccagc ctacccaaca tggtgaaatc tcatctctac taaaaataca aaaattagct
20761 gggtgtgttg gcacatgccc gtaatcccag ctacttggga ggctgaggca ggagaattgc
20821 ttgaacccag gaggcagagg ttgcagtgag ccgagatcat gccactgcac tccagcctgg
20881 gtgacagagc gagactccat ctcacaaaaa aaaaaaaaaa aaaaaaagag acagtgatct
20941 cagcttatgc catactctat gcactgggtt cttcctgcgt caggctttta cccctgggcc
21001 aggcccacat tttaaaacat tattatttac ttgtttatta ttttatttta gagataggat
21061 cttgctatgc tgcccaggct ggactgctgt ggctattcac aggttcaatt catgatgctc
21121 tacagccttg aactcctggg ctccagcgat cctcctgtct cagcctgctg agtggctgaa
21181 ctacacgtgt gagtcactgc acctggccat ggcccacagt tttaaagacc agctagatgg
21241 ttccagagga actctgtctt ctgcttgtaa cccgtccctc tcttgcctcc atccttcatg
21301 attctgggat tccatgctat gagaagagat ctagaaagcc gggagctgag ttggactcct
21361 gtatcatcct catgccccca ccccaccagc tcaatggaaa atgagacctg gaactcaggc
21421 ttgaggccag actgagtgtg agtcttagct ctggaggagt cacttaaaat ctaagccaac
21481 atttccaatg ttgcatgtaa aggggataat catagaactg attaacttat ataaaaagtt
21541 tttatctggc caggcgtggt ggctcatgcc tgtaatccca gcactttggg aggccgaggc
21601 gggcagatca cctaaggtca ggagtttgag gccatcctgg gcaacatggt gaaaccccgt
21661 ctctaccaaa aatacaaaaa ttagctgggc atggtggcgg gtgcctctga tcccagctac
21721 ttgggaggct aaggcagaag aattgcttga acctgggagg cggaggttgt agtgaaccga
21781 aatcgcacca catcactcca gcctgggtga cagagcaaga ctgtctctca aaaacaaaca
21841 aacaaacaaa caaaaaggtt ttatccatca tgagtgctca acaaaataat agtatcatga
21901 tttccccatc agtcacctgc ctggccttcc ctgttgtcaa atcctttcct ttagtctgag
21961 tcatttctca ccttgaccat tatctggtct ccttcccatc catcctcctg ctgcatgcag
22021 tctataccca ccactcctca tctttgttgc tcctagatcc agccttgcat gcattcctcc
22081 tctctaaccc tttattgtct cccacactct aaagaacata tgcaagccac atctgtaatt
22141 tccaattttc tagtggctac attattttta aacagtaaaa acaaatagat gaaatgattt
22201 tttaatgata tattctattt aacataataa atccccaata ttaccaattc aacctataat
22261 caatataaaa attagttact agatagttta aacttgtttt tcttttgtat tcacacttca
22321 aaatctggta tgtattttat attcatgtct tggataattt gctcaagtgg ataatctggt
22381 cagccaagtg gtcaagagct acatatgcct tgtgaagaga ccactttggt tgaggggatg
22441 caattcagcc tccttcccat gacacagcct ttgaaggctg gctcaggctt ggtcccaagt
22501 cccatttctt gtgcaccctc tctccctgtt tctgccatgt taagccaact gcaactgatc
22561 aaacacccga gtctcttggt tgcttctaaa cctttgccca agctgtttac tgccaggact
22621 tcctgtccct ttgttgtggc ctccatctgg ctgcactgac tcggggctcc acaactgtct
22681 caaatctcac tccttgggca agacttcccc gagctcttca tgcagttatt aacttcctcc
22741 actgtgcaaa cagcatgttt tcctaactat atttagcttc tactgcacag ttataaattt
22801 atttagcaaa gctccctccc ctactaatct gcagattctc agtgggcagg atctactcaa
22861 cccattgatg tgcctgataa acacttggca attagacagt tgaatgaaca aatgaatgaa
22921 tgtgtaactg aatgaatttt cgggttccaa ggaccctgac attctgggat cccattaggt
22981 ggctggggtc accaccttag agaattgtga ttccctaaga agggagaacc agcccagacc
23041 ttctcgatca tattagtgac tggccacatt tcctctcctt tctgattctc tctctccccc
23101 acacccttac tgcatgacag tgatgagaaa atccacttga tcaaccaaac tacaactttc
23161 ggcctcatcc ctatccctcc cttgccttct gaccagggcc acagtcaccc tgtgggttct
23221 tccttttgag tgtctctcac tcccttcctc ctccatatct ctgagaccag cctccagccc
23281 tgctggcctg ctctgctgcc ttctggctct ttgttgaacc caagaccagg gtttatatat
23341 gttaaatata aatatatttt tccatatgaa atgtaaacat attttaaaca ttaaatataa
23401 atatacatct tagatatggc ctgtgttgga atgtgtaata gattgagtat ataatgtcta
23461 ttcaatataa aatttatatt tatatatgca gtaatgattc aggttgattg tagttaagaa
23521 aaacaagctc caaattcgag agaaatatgt aagaagagag acaggaagaa aaaataatga
23581 ggcaggtaaa tgcaacagac aattcgagac ccacaagtgc agagcaggct tcccagaccc
23641 ggataatgtc tcctgggctg ataggaagcc ctcaaccccc caagtccttc tcagccataa
23701 accgcctgag cacagagcca cagggaccgt gttggggctg ggcctctcga ctttagttcc
23761 tctcattctg tgcaaaagga aaaacaattc agaatctaca gaggtttaga tgtgtgtaga
23821 tgtggacaga gaagtcctgg cacggtggtt cactgcccaa gaagacagtg agtccctgga
23881 gggatagaag aatatacatc atgctaatat atgtcatccc agtactttgg gaggccgagg
23941 cgggtggatc acttgaggtc aagagttcga gaccagcctg gccaacatgg tgaatccccg
24001 tctctactaa aaatacagaa attagttggc tgtgggggtc gatgcctgtg atcccagata
24061 ctcgggagac agaggcagga cgaactgctt gaacctggga ggaggaggtt gcagtgagct
24121 gagatcatgc cg
//