LOCUS BC110618 2452 bp mRNA linear HUM 04-OCT-2006
DEFINITION Homo sapiens receptor-interacting serine-threonine kinase 4, mRNA
(cDNA clone MGC:129993 IMAGE:40034396), complete cds.
ACCESSION BC110618
VERSION BC110618.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2452)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2452)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 14 Row: I Column: 24.
FEATURES Location/Qualifiers
source 1..2452
/db_xref="H-InvDB:HIT000339652"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:129993 IMAGE:40034396"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: TAATCAAA sequenced from the reverse primer"
gene 1..2452
/gene="RIPK4"
/gene_synonym="ANKK2"
/gene_synonym="DIK"
/gene_synonym="PKK"
/gene_synonym="RIP4"
/db_xref="GeneID:54101"
/db_xref="HGNC:HGNC:496"
/db_xref="MIM:605706"
CDS 22..2376
/gene="RIPK4"
/gene_synonym="ANKK2"
/gene_synonym="DIK"
/gene_synonym="PKK"
/gene_synonym="RIP4"
/codon_start=1
/product="receptor-interacting serine-threonine kinase 4"
/protein_id="AAI10619.1"
/db_xref="GeneID:54101"
/db_xref="HGNC:HGNC:496"
/db_xref="MIM:605706"
/translation="MEGDGGTPWALALLRTFDAGEFTGWEKVGSGGFGQVYKVRHVHW
KTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICREPVGLVMEYMETG
SLEKLLASEPLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKIS
DFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLT
QKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTF
QEITSETEDLCEKPDDEVKETAHDLDVKSPPEPRSEVVPARLKRASAPTFDNDYSLSE
LLSQLDSGVSQAVEGPEELSRSSSESKLPSSGSGKRLSGVSSVDSAFSSRGSLSLSFE
REPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQDVDLALDSGASLLHLAVEAGQ
EECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTAL
HFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQ
GKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILI
DLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGH
LATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVIDLFDEQGLSALH
LAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRRSKT"
BASE COUNT 472 a 765 c 799 g 416 t
ORIGIN
1 ggcgctggct agacgtgcgc gatggagggc gacggcggga ccccatgggc cctggcgctg
61 ctgcgcacct tcgacgcggg cgagttcacg ggctgggaga aggtgggctc gggcggcttc
121 gggcaggtgt acaaggtgcg ccatgtccac tggaagacct ggctggccat caagtgctcg
181 cccagcctgc acgtcgacga cagggagcgc atggagcttt tggaagaagc caagaagatg
241 gagatggcca agtttcgcta catcctgcct gtgtatggca tctgccgcga acctgtcggc
301 ctggtcatgg agtacatgga gacgggctcc ctggaaaagc tgctggcttc ggagccattg
361 ccatgggatc tccggttccg aatcatccac gagacggcgg tgggcatgaa cttcctgcac
421 tgcatggccc cgccactcct gcacctggac ctcaagcccg cgaacatcct gctggatgcc
481 cactaccacg tcaagatttc tgattttggt ctggccaagt gcaacgggct gtcccactcg
541 catgacctca gcatggatgg cctgtttggc acaatcgcct acctccctcc agagcgcatc
601 agggagaaga gccggctctt cgacaccaag cacgatgtat acagctttgc gatcgtcatc
661 tggggcgtgc tcacacagaa gaagccgttt gcagatgaga agaacatcct gcacatcatg
721 gtgaaggtgg tgaagggcca ccgccccgag ctgccgcccg tgtgcagagc ccggccgcgc
781 gcctgcagcc acctgatacg cctcatgcag cggtgctggc agggggatcc gcgagttagg
841 cccaccttcc aagaaattac ttctgaaacc gaggacctgt gtgaaaagcc tgatgacgaa
901 gtgaaagaaa ctgctcatga tctggacgtg aaaagccccc cggagcccag gagcgaggtg
961 gtgcctgcga ggctcaagcg ggcctctgcc cccaccttcg ataacgacta cagcctctcc
1021 gagcttctct cacagctgga ctctggagtt tcccaggctg tcgagggccc cgaggagctc
1081 agccgcagct cctctgagtc caagctgcca tcgtccggca gtgggaagag gctctcgggg
1141 gtgtcctcgg tggactccgc cttctcttcc agaggatcac tgtcgctgtc ctttgagcgg
1201 gaaccttcaa ccagcgatct gggtaccaca gacgtccaga agaagaagct tgtggatgcc
1261 atcgtgtccg gggacaccag caaactgatg aagatcctgc agccgcagga cgtggacctg
1321 gcactggaca gcggtgccag cctgctgcac ctggcggtgg aggccgggca agaggagtgc
1381 gccaagtggc tgctgctcaa caatgccaac cccaacctga gcaaccgtag gggctccacc
1441 ccgttgcaca tggccgtgga gaggagggtg cggggtgtcg tggagctcct gctggcacgg
1501 aagatcagtg tcaacgccaa ggatgaggac cagtggacag ccctccactt tgcagcccag
1561 aacggggatg agtctagcac acggctgctg ttggagaaga acgcctcggt caacgaggtg
1621 gactttgagg gccggacgcc catgcacgtg gcctgccagc acgggcagga gaatatcgtg
1681 cgcatcctgc tgcgccgagg cgtggacgtg agcctgcagg gcaaggatgc ctggctgcca
1741 ctgcactacg ctgcctggca gggccacctg cccatcgtca agctgctggc caagcagccg
1801 ggggtgagtg tgaacgccca gacgctggat gggaggacgc cattgcacct ggccgcacag
1861 cgcgggcact accgcgtggc ccgcatcctc atcgacctgt gctccgacgt caacgtctgc
1921 agcctgctgg cacagacacc cctgcacgtg gccgcggaga cggggcacac gagcactgcc
1981 aggctgctcc tgcatcgggg cgctggcaag gaggccgtga cctcagacgg ctacaccgct
2041 ctgcacctgg ctgcccgcaa cggacacctg gccactgtca agctgcttgt cgaggagaag
2101 gccgatgtgc tggcccgggg acccctgaac cagacggcgc tgcacctggc tgccgcccac
2161 gggcactcgg aggtggtgga ggagttggtc agcgccgatg tcattgacct gttcgacgag
2221 caggggctca gcgcgctgca cctggccgcc cagggccggc acgcacagac ggtggagact
2281 ctgctcaggc atggggccca catcaacctg cagagcctca agttccaggg cggccatggc
2341 cccgccgcca cactcctgcg gcgaagcaag acctagctgg ctgcctgcgg agaccggggg
2401 tccacgtggg gctcttgtcc tgtcctgtgt tcctcgtggg gatggaacga tc
//