LOCUS BC069600 1640 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2,
mRNA (cDNA clone MGC:97102 IMAGE:7262323), complete cds.
ACCESSION BC069600
VERSION BC069600.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1640)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1640)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRBR Plate: 3 Row: d Column: 5.
FEATURES Location/Qualifiers
source 1..1640
/db_xref="H-InvDB:HIT000263751"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:97102 IMAGE:7262323"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_277"
/note="Vector: pPCR-Script Amp SK(+) with reversed insert"
gene 1..1640
/gene="PFKFB2"
/gene_synonym="PFK-2/FBPase-2"
/db_xref="GeneID:5208"
/db_xref="HGNC:HGNC:8873"
/db_xref="MIM:171835"
CDS 51..1568
/gene="PFKFB2"
/gene_synonym="PFK-2/FBPase-2"
/codon_start=1
/product="6-phosphofructo-2-kinase/fructose-2,
6-biphosphatase 2"
/protein_id="AAH69600.1"
/db_xref="GeneID:5208"
/db_xref="HGNC:HGNC:8873"
/db_xref="MIM:171835"
/translation="MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMI
GLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIR
KQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDD
PDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKV
INVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSV
RGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEE
MTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQ
AVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPT
NNFPKNQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSPLRAQDMQEGAD"
BASE COUNT 446 a 396 c 420 g 378 t
ORIGIN
1 aaggcaggga gggatcttag gagagatcgt aggacatctg aagagctgcc atgtctgggg
61 catcttcctc agaacagaac aacaacagct atgaaaccaa aaccccaaat cttcgaatgt
121 cagagaagaa atgttcatgg gcctcctaca tgaccaactc cccgactctg atcgttatga
181 ttggtttgcc agcccggggt aaaacctacg tgtccaagaa actaacacgc tacctcaact
241 ggattggagt ccccaccaaa gtgtttaatc ttggggtgta tcggcgtgaa gcagtcaagt
301 cctataagtc ctacgacttc tttcggcatg acaatgagga ggccatgaag atccgcaaac
361 agtgtgctct ggtggcgctg gaagatgtta aggcgtatct cactgaggag aatggtcaga
421 ttgcggtgtt tgatgccacc aatacaaccc gggagaggag ggacatgatt ttgaactttg
481 ctgaacagaa ttccttcaag gtattctttg tggaatccgt ctgtgatgat cctgatgtca
541 ttgctgccaa tattctggag gttaaggtat caagccctga ctatcctgaa aggaatagag
601 agaacgtgat ggaggacttc ctgaagagaa ttgaatgcta caaagttacc taccgacctc
661 ttgacccaga caactatgac aaggatcttt ctttcatcaa ggtgataaac gtgggccagc
721 gatttttagt caacagagtc caggactaca tccagagcaa gatagtctac tacctcatga
781 atatccacgt ccagcctcgc accatttacc tttgccggca tggagaaagc gagttcaatc
841 tcttggggaa gattgggggt gactctggcc tctcggtgcg gggaaagcag tttgcccaag
901 ctctaaggaa atttctggag gaacaggaaa taacagacct caaagtgtgg acaagccagt
961 tgaagaggac catacagact gctgaatctc tcggggtgcc ctatgagcag tggaagattc
1021 tgaatgagat tgatgctggt gtgtgtgaag agatgaccta tgcagagatt gagaaacggt
1081 acccagaaga gtttgcactt cgagatcaag agaagtatct gtatcgatat cctggtgggg
1141 agtcatacca ggacctggtg cagcggctgg agcctgtcat catggagctg gaacgtcagg
1201 gcaatgtcct cgtcatctcc caccaggctg tcatgcgctg cctcctggcc tacttcttgg
1261 ataagggcgc agatgagcta ccatacttga gatgccctct ccataccatc ttcaaactta
1321 ctcctgtggc ctatgggtgc aaagtggaaa caattaaact taacgtggag gctgtgaaca
1381 cgcaccgtga caagccaact aacaacttcc ccaagaacca aacccctgta aggatgagaa
1441 ggaacagctt tacgcctctg tccagttcga atacaataag gcgtccaaga aattacagtg
1501 ttgggagccg gcccctcaag cccctcagcc ctctccgtgc ccaggacatg caagaagggg
1561 ccgactagcc gaagacccaa gtcagcattc cggtggtgta actgtgtgtt tccctccagc
1621 cctggcctcc tgcccttgtc
//