LOCUS BC029620 1085 bp mRNA linear ROD 04-OCT-2003
DEFINITION Mus musculus histocompatibility 2, class II antigen A, alpha, mRNA
(cDNA clone MGC:25392 IMAGE:2609494), complete cds.
ACCESSION BC029620
VERSION BC029620.1
KEYWORDS MGC.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 1085)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1085)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (06-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Jeffrey Green M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 30 Row: a Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13540710.
FEATURES Location/Qualifiers
source 1..1085
/organism="Mus musculus"
/mol_type="mRNA"
/strain="FVB/N"
/db_xref="taxon:10090"
/clone="MGC:25392 IMAGE:2609494"
/tissue_type="Mammary tumor. C3(1)-Tag model. Infiltrating
ductal carcinoma. 5 month old virgin mouse."
/clone_lib="NCI_CGAP_Mam6"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1085
/gene="H2-Aa"
/gene_synonym="Aalpha"
/db_xref="GeneID:14960"
/db_xref="MGI:MGI:95895"
CDS 31..801
/gene="H2-Aa"
/gene_synonym="Aalpha"
/codon_start=1
/product="H2-Aa protein"
/protein_id="AAH29620.1"
/db_xref="GeneID:14960"
/db_xref="MGI:MGI:95895"
/translation="MPCSRALILGVLALTTMLSLCGGEDDIEADHVGFYGIVVYQSPG
DIGQYTHEFDGDEWFYVDLDKKETVWMLPEFGQLTSFDPQGGLQNIATGKHNLGGWTK
RSNFTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVY
ETSFLVNRDHSFHKLSYLTFIPSDDDIYDCKVEHWGLDEPVLKHWEPEIPAPMSELTE
TVVCALGLSVGLVGIVVGTIFIIQGLRSGGTSRPPGPL"
misc_feature 118..363
/gene="H2-Aa"
/gene_synonym="Aalpha"
/note="MHC_II_alpha; Region: Class II histocompatibility
antigen, alpha domain"
/db_xref="CDD:pfam00993"
misc_feature 415..630
/gene="H2-Aa"
/gene_synonym="Aalpha"
/note="IGc1; Region: Immunoglobulin C-Type"
/db_xref="CDD:smart00407"
BASE COUNT 264 a 293 c 253 g 275 t
ORIGIN
1 agcagctgca gagacctccc agagaccagg atgccgtgca gcagagctct gattctgggg
61 gtcctcgccc tgaccaccat gctcagcctc tgtggaggtg aagacgacat tgaggccgac
121 catgtaggct tctatggtat agttgtatat cagtctcctg gagacattgg ccagtataca
181 catgaatttg atggtgatga gtggttctat gtggacttgg ataagaagga gactgtctgg
241 atgcttcctg agtttggcca attgacaagc tttgaccccc aaggtggact acaaaacata
301 gctacaggaa aacacaactt gggaggctgg actaagaggt caaatttcac cccagctacc
361 aatgaggctc ctcaagcaac tgtgttcccc aagtcccctg tgctgctggg tcagcccaat
421 acccttatct gctttgtgga caacatcttc cctcctgtga tcaacatcac atggctcaga
481 aatagcaagt cagtcacaga cggcgtttat gagaccagct tccttgtcaa ccgtgaccat
541 tccttccaca agctgtctta tctcaccttc atcccttctg acgatgacat ttatgactgc
601 aaggtggaac actggggcct ggacgagcca gttctgaaac actgggaacc tgagatccca
661 gcccccatgt cagagctgac agagactgtg gtctgtgccc tggggttgtc tgtgggcctt
721 gtgggcatcg tggtgggaac catcttcatc attcaaggcc tgcgatcagg tggcacctcc
781 agacccccag gacctttatg agtcacaccc tggaaaggaa ggcatgtgtc cctcttcagg
841 gaagaagtgg tgtgctgggt gacctggacc aattcttggt gttctttctc atcttcaagt
901 aacccccaac ttgcttttcc ctttgctccg gaggctgtcc ctctcacagc tcacacaccc
961 gtggaattct tccctgatct gaattttgtt ttctggcatc ttccaagtca catctactgc
1021 agactctctc agagaccctg atccacaaaa ccaataaaat ctcttcttat aaaaaaaaaa
1081 aaaaa
//