LOCUS BC029227 2803 bp mRNA linear ROD 02-DEC-2006
DEFINITION Mus musculus icos ligand, mRNA (cDNA clone MGC:35971
IMAGE:4217333), complete cds.
ACCESSION BC029227
VERSION BC029227.1
KEYWORDS MGC.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 2803)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2803)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Jeffrey E. Green, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 61 Row: k Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31980683.
FEATURES Location/Qualifiers
source 1..2803
/organism="Mus musculus"
/mol_type="mRNA"
/strain="FVB/N"
/db_xref="taxon:10090"
/clone="MGC:35971 IMAGE:4217333"
/tissue_type="Colon, normal. 5 month old male mouse."
/clone_lib="NCI_CGAP_Co24"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2803
/gene="Icosl"
/gene_synonym="B7-H2"
/gene_synonym="B7h"
/gene_synonym="B7RP-1"
/gene_synonym="GI50"
/gene_synonym="GL50"
/gene_synonym="GL50-B"
/gene_synonym="ICOS-L"
/gene_synonym="LICOS"
/gene_synonym="Ly115l"
/gene_synonym="mKIAA0653"
/db_xref="GeneID:50723"
/db_xref="MGI:MGI:1354701"
CDS 158..1126
/gene="Icosl"
/gene_synonym="B7-H2"
/gene_synonym="B7h"
/gene_synonym="B7RP-1"
/gene_synonym="GI50"
/gene_synonym="GL50"
/gene_synonym="GL50-B"
/gene_synonym="ICOS-L"
/gene_synonym="LICOS"
/gene_synonym="Ly115l"
/gene_synonym="mKIAA0653"
/codon_start=1
/product="icos ligand"
/protein_id="AAH29227.1"
/db_xref="GeneID:50723"
/db_xref="MGI:MGI:1354701"
/translation="MQLKCPCFVSLGTRQPVWKKLHVSSGFFSGLGLFLLLLSSLCAA
SAETEVGAMVGSNVVLSCIDPHRRHFNLSGLYVYWQIENPEVSVTYYLPYKSPGINVD
SSYKNRGHLSLDSMKQGNFSLYLKNVTPQDTQEFTCRVFMNTATELVKILEEVVRLRV
AANFSTPVISTSDSSNPGQERTYTCMSKNGYPEPNLYWINTTDNSLIDTALQNNTVYL
NKLGLYDVISTLRLPWTSRGDVLCCVENVALHQNITSISQAESFTGNNTKNPQETHNN
ELKVLVPVLAVLAAAAFVSFIIYRRTRPHRSYTGPKTVQLELTDHA"
BASE COUNT 715 a 746 c 682 g 660 t
ORIGIN
1 agcgggtctc ctgccgccaa agcctcaaga accccagatt tcagcgcccc aagcctggaa
61 gctccccagt tcttcgtggc ccccaacagc tccggaaccc cagccgctgc aactctccgc
121 gtccgaaatc cagcaccccg cagtctgcgc tcgcaccatg cagctaaagt gtccctgttt
181 tgtgtccttg ggaaccaggc agcctgtttg gaagaagctc catgtttcta gcgggttctt
241 ttctggtctt ggtctgttct tgctgctgtt gagcagcctc tgtgctgcct ctgcagagac
301 tgaagtcggt gcaatggtgg gcagcaatgt ggtgctcagc tgcattgacc cccacagacg
361 ccatttcaac ttgagtggtc tgtatgtcta ttggcaaatc gaaaacccag aagtttcggt
421 gacttactac ctgccttaca agtctccagg gatcaatgtg gacagttcct acaagaacag
481 gggccatctg tccctggact ccatgaagca gggtaacttc tctctgtacc tgaagaatgt
541 cacccctcag gatacccagg agttcacatg ccgggtattt atgaatacag ccacagagtt
601 agtcaagatc ttggaagagg tggtcaggct gcgtgtggca gcaaacttca gtacacctgt
661 catcagcacc tctgatagct ccaacccggg ccaggaacgt acctacacct gcatgtccaa
721 gaatggctac ccagagccca acctgtattg gatcaacaca acggacaata gcctaataga
781 cacggctctg cagaataaca ctgtctactt gaacaagttg ggcctgtatg atgtaatcag
841 cacattaagg ctcccttgga catctcgtgg ggatgttctg tgctgcgtag agaatgtggc
901 tctccaccag aacatcacta gcattagcca ggcagaaagt ttcactggaa ataacacaaa
961 gaacccacag gaaacccaca ataatgagtt aaaagtcctt gtccccgtcc ttgctgtact
1021 ggcggcagcg gcattcgttt ccttcatcat atacagacgc acgcgtcccc accgaagcta
1081 tacaggaccc aagactgtac agcttgaact tacagaccac gcctgacagg actctgccca
1141 ggatatggac agggtttctg tgagttgcca ccaggtggat gtcagacaca acttcagagt
1201 ggacccccac aggcctggtg acagaggaca acgagctgtc tgcttatggg ctgtgatgga
1261 ggccaggaat ccctggcttt acgaggcaca gagacttcat cccagaaacc ccgagggaga
1321 tctctccagt gggcagcagc aacatcatcg gaatatggag cctccggtga gctgtcggca
1381 cagagagcag cagcttgtga gaagatcctt ccttggcacg ttactactca ggcctaggag
1441 ctttataaaa gagcgtttga gccactctga aagccctaca gagtctactg gagactttcc
1501 ctgcaggacc ttcagttggg gaggaagcct gactttattt aggtctcagg ctacttgggc
1561 ctcttcgagg atatgtggga ttttgtctac tgcaaacctg tttctggctg acaatggttg
1621 ggctcagagg cactcagctt cacaacatca atgggacacg cctcatcctt gacttcctgt
1681 ggctacagaa gctttccgaa agccttgagc tctttcagac tgaacagctc tgcccagtct
1741 cagcagccca tgaagatctc aactccagct tcctgggtct ccgtgttgct ggccagaata
1801 gagctagctc ttttgtttca agatggttct gcaaagttgg ctgcttggaa acctagggat
1861 gtatgtacaa gctccaggct gatgcagtag ggggcacgga ctccccgatg gaacacagta
1921 tctgacccta ggtgagggca agctccttcc cacgcagagg actggaaatt ctggaccgtc
1981 aaggcctgtc tgctatgtgg ctggggctca gtgctgatgg atgtgtgaga tctcaggaat
2041 gaggagtgag aaccctgggc tcaggactag gaagacctgt ccattttttt ttttttttaa
2101 tgcccacatg gactttttat tcttcacacc gatgtattca atgagtgtag agagaactac
2161 ttaagtcctt cccgagtaca aagcattacc tacctgcaga atagcaactg ttgttatggg
2221 tcttgagttg gcagctacag caaacaagca caaggagcag ttggggtgca agaagatggg
2281 gtgcagcgcc cccaaggaca gacatttggg aattagtggt ctccctgatg cccatagttc
2341 cccaggaact caggtgggtc tgcggcagca cagtaggagt attcctccta ctttaacttt
2401 tcttgtcaga cgtagtttag gttcagaaag aggtcaactc agcaagccag ctagccgcct
2461 tggggcacca gacacactgc cccccacccc ctgcttatgt aggcattggg aacccttcac
2521 agaccactgg ctgtacagtc accatcacct gctgattcca gcaggccccc accttcttgt
2581 ggaatcctgg gagcactccc ctcttacccc tcactgcccc ccaccccctg cacatcagca
2641 ttcattagat ttgccctgta acgtctgatt cctcctttat ctgggttgta gatggggcat
2701 agtgactttt agaaacctaa caagggaata aatgtaagat gtgctttcaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
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