LOCUS BC028073 2493 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens CD244 molecule, natural killer cell receptor 2B4, mRNA
(cDNA clone MGC:39928 IMAGE:5213370), complete cds.
ACCESSION BC028073
VERSION BC028073.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2493)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2493)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: g Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51593100.
FEATURES Location/Qualifiers
source 1..2493
/db_xref="H-InvDB:HIT000259002"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39928 IMAGE:5213370"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2493
/gene="CD244"
/gene_synonym="2B4"
/gene_synonym="NAIL"
/gene_synonym="NKR2B4"
/gene_synonym="Nmrk"
/gene_synonym="SLAMF4"
/db_xref="GeneID:51744"
/db_xref="HGNC:HGNC:18171"
/db_xref="MIM:605554"
CDS 226..1323
/gene="CD244"
/gene_synonym="2B4"
/gene_synonym="NAIL"
/gene_synonym="NKR2B4"
/gene_synonym="Nmrk"
/gene_synonym="SLAMF4"
/codon_start=1
/product="CD244 molecule, natural killer cell receptor
2B4"
/protein_id="AAH28073.1"
/db_xref="GeneID:51744"
/db_xref="HGNC:HGNC:18171"
/db_xref="MIM:605554"
/translation="MLGQVVTLILLLLLKVYQGKGCQGSADHVVSISGVPLQLQPNSI
QTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNLSLLIKAAQQQDS
GLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVALSCLVSRDGNV
SYAWYRGSKLIQTAGNLTYLDEEVDINGTHTYTCNVSNPVSWESHTLNLTQDCQNAHQ
EFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEFLTIYEDVKDLKTRR
NHEQEQTFPGGGSTIYSMIQSQSSAPTSQEPAYTLYSLIQPSRKSGSRKRNHSPSFNS
TIYEVIGKSQPKAQNPARLSRKELENFDVYS"
BASE COUNT 665 a 564 c 643 g 621 t
ORIGIN
1 cttgtgggaa ctgtcagacc agctccaggc gctggggctt tctcagtggc cttgtcagct
61 cacagcaggc gttaacagcc tctaattgag gaaactgtgg ctggacaggt tgcaaggcag
121 ttctgctccc catcgtcctc ttgctgactg gggactgctg agcccgtgca cggcagagag
181 tctggtgggg tggaggggct ggcctggccc ctctgtcctg tggaaatgct ggggcaagtg
241 gtcaccctca tactcctcct gctcctcaag gtgtatcagg gcaaaggatg ccagggatca
301 gctgaccatg tggttagcat ctcgggagtg cctcttcagt tacaaccaaa cagcatacag
361 acgaaggttg acagcattgc atggaagaag ttgctgccct cacaaaatgg atttcatcac
421 atattgaagt gggagaatgg ctctttgcct tccaatactt ccaatgatag attcagtttt
481 atagtcaaga acttgagtct tctcatcaag gcagctcagc agcaggacag tggcctctac
541 tgcctggagg tcaccagtat atctggaaaa gttcagacag ccacgttcca ggtttttgta
601 tttgataaag ttgagaaacc ccgcctacag gggcagggga agatcctgga cagagggaga
661 tgccaagtgg ctctgtcttg cttggtctcc agggatggca atgtgtccta tgcttggtac
721 agagggagca agctgatcca gacagcaggg aacctcacct acctggacga ggaggttgac
781 attaatggca ctcacacata tacctgcaat gtcagcaatc ctgttagctg ggaaagccac
841 accctgaatc tcactcagga ctgtcagaat gcccatcagg aattcagatt ttggccgttt
901 ttggtgatca tcgtgattct aagcgcactg ttccttggca cccttgcctg cttctgtgtg
961 tggaggagaa agaggaagga gaagcagtca gagaccagtc ccaaggaatt tttgacaatt
1021 tacgaagatg tcaaggatct gaaaaccagg agaaatcacg agcaggagca gacttttcct
1081 ggagggggga gcaccatcta ctctatgatc cagtcccagt cttctgctcc cacgtcacaa
1141 gaacctgcat atacattata ttcattaatt cagccttcca ggaagtctgg atccaggaag
1201 aggaaccaca gcccttcctt caatagcact atctatgaag tgattggaaa gagtcaacct
1261 aaagcccaga accctgctcg attgagccgc aaagagctgg agaactttga tgtttattcc
1321 tagttgctgc agcaattctc acctttcttg cacatcagca tctgctttgg gaattggcac
1381 agtggatgac ggcacaggag tctctataga acagttccta gtctggagag gatatggaaa
1441 tttgttcttg ttctatattt tgttttgaaa atgatgtcta acaaccatga taagagcaag
1501 gctgttaaat aatatcttcc aatttacaga tcagacatga atgggtggag gggttaggtt
1561 gttcacaaaa ggccacattc caagtatttg taatctagaa agtgttatgt aagtgatgtt
1621 attagcatcg agattccctc cacctgattt tcaagctgtc acttgtttcc ttttctcccc
1681 tctctgggtt gactgcattt ctagactctc gccggcccag gcccatcttc caaagcaaga
1741 ggaaggaatg ataatggtga ctcaggggaa gaagaaacag ccctcctctg aaagcctgga
1801 ctgtccggct gtgaactggc tggcaggttc tgcacgtggg tgggggccag ggcctgggct
1861 ttactcaatt gcagagaaaa aactttctcc ctgcatctca tacctttacc tctggccagt
1921 tggccaccag ggggagtggg ctgaagggag agtagatggt gcaaagcaag cccatctcta
1981 agtagaaaaa tcacccagag cacatgctga cctgataact ggggtgttga gaccagcttt
2041 gtccatggta tgatgtttga tttatgaaga cgcattgtta gaaatccatt tggcttcttc
2101 atagaagtgg cttcccagag gaagaggcct ctcagaaacc atgttctatt taagttctga
2161 gtcctgatga gtgttcccca ggatgcacat tgaagggagg gctcaggcag ctgagggctg
2221 agaatgaggc agttggaatc tagacactat gctgggttcc ctgagtcgtc aggccagaca
2281 tttcaacaag gctgtgggga gcagggctgt gactctggct gagcccagga aagcgacaag
2341 ggtgaactgg gagaggactt actcagagac cccaacaggt gatactgcac aaagcctggt
2401 tcttcaattt tcctaccctg tatctaacat aggagtttca tataaaacgg tgatatcatg
2461 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
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