LOCUS BC027258 2704 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens B-cell CLL/lymphoma 2, mRNA (cDNA clone MGC:21366
IMAGE:4511027), complete cds.
ACCESSION BC027258
VERSION BC027258.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2704)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2704)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 28 Row: h Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557356.
FEATURES Location/Qualifiers
source 1..2704
/db_xref="H-InvDB:HIT000040253"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21366 IMAGE:4511027"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2704
/gene="BCL2"
/gene_synonym="Bcl-2"
/db_xref="GeneID:596"
/db_xref="HGNC:HGNC:990"
/db_xref="MIM:151430"
CDS 390..1109
/gene="BCL2"
/gene_synonym="Bcl-2"
/codon_start=1
/product="B-cell CLL/lymphoma 2"
/protein_id="AAH27258.1"
/db_xref="GeneID:596"
/db_xref="HGNC:HGNC:990"
/db_xref="MIM:151430"
/translation="MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAP
APGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGD
DFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVE
SVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLK
TLLSLALVGACITLGAYLGHK"
BASE COUNT 694 a 660 c 728 g 622 t
ORIGIN
1 ctggagagtg ctgaagattg atgggatcgt tgccttatgc atttgttttg gttttacaaa
61 aaggaaactt gacagaggat catgctgtac ttaaaaaata caacatcaca gaggaagtag
121 actgatatta acaatactta ctaataataa cgtgcctcat gaaataaaga tccgaaagga
181 attggaataa aaatttcctg catctcatgc caagggggaa acaccagaat caagtgttcc
241 gcgtgattga agacaccccc tcgtccaaga atgcaaagca catccaataa aatagctgga
301 ttataactcc tcttctttct ctgggggccg tggggtggga gctggggcga gaggtgccgt
361 tggcccccgt tgcttttcct ctgggaagga tggcgcacgc tgggagaacg gggtacgata
421 accgggagat agtgatgaag tacatccatt ataagctgtc gcagaggggc tacgagtggg
481 atgcgggaga tgtgggcgcc gcgcccccgg gggccgcccc cgcaccgggc atcttctcct
541 cccagcccgg gcacacgccc catccagccg catcccggga cccggtcgcc aggacctcgc
601 cgctgcagac cccggctgcc cccggcgccg ccgcggggcc tgcgctcagc ccggtgccac
661 ctgtggtcca cctgaccctc cgccaggccg gcgacgactt ctcccgccgc taccgccgcg
721 acttcgccga gatgtccagc cagctgcacc tgacgccctt caccgcgcgg ggacgctttg
781 ccacggtggt ggaggagctc ttcagggacg gggtgaactg ggggaggatt gtggccttct
841 ttgagttcgg tggggtcatg tgtgtggaga gcgtcaaccg ggagatgtcg cccctggtgg
901 acaacatcgc cctgtggatg actgagtacc tgaaccggca cctgcacacc tggatccagg
961 ataacggagg ctgggatgcc tttgtggaac tgtacggccc cagcatgcgg cctctgtttg
1021 atttctcctg gctgtctctg aagactctgc tcagtttggc cctggtggga gcttgcatca
1081 ccctgggtgc ctatctgggc cacaagtgaa gtcaacatgc ctgccccaaa caaatatgca
1141 aaaggttcac taaagcagta gaaataatat gcattgtcag tgatgtacca tgaaacaaag
1201 ctgcaggctg tttaagaaaa aataacacac atataaacat cacacacaca gacagacaca
1261 cacacacaca acaattaaca gtcttcaggc aaaacgtcga atcagctatt tactgccaaa
1321 gggaaatatc atttattttt tacattatta agaaaaaaag atttatttat ttaagacagt
1381 cccatcaaaa ctcctgtctt tggaaatccg accactaatt gccaagcacc gcttcgtgtg
1441 gctccacctg gatgttctgt gcctgtaaac atagattcgc tttccatgtt gttggccgga
1501 tcaccatctg aagagcagac ggatggaaaa aggacctgat cattggggaa gctggctttc
1561 tggctgctgg aggctgggga gaaggtgttc attcacttgc atttctttgc cctgggggct
1621 gtgatattaa cagagggagg gttcctgtgg ggggaagtcc atgcctccct ggcctgaaga
1681 agagactctt tgcatatgac tcacatgatg catacctggt gggaggaaaa gagttgggaa
1741 cttcagatgg acctagtacc cactgagatt tccacgccga aggacagcga tgggaaaaat
1801 gcccttaaat cataggaaag tattttttta agctaccaat tgtgccgaga aaagcatttt
1861 agcaatttat acaatatcat ccagtacctt aagccctgat tgtgtatatt catatatttt
1921 ggatacgcac cccccaactc ccaatactgg ctctgtctga gtaagaaaca gaatcctctg
1981 gaacttgagg aagtgaacat ttcggtgact tccgcatcag gaaggctaga gttacccaga
2041 gcatcaggcc gccacaagtg cctgctttta ggagaccgaa gtccgcagaa cctgcctgtg
2101 tcccagcttg gaggcctggt cctggaactg agccggggcc ctcactggcc tcctccaggg
2161 atgatcaaca gggcagtgtg gtctccgaat gtctggaagc tgatggagct cagaattcca
2221 ctgtcaagaa agagcagtag aggggtgtgg ctgggcctgt caccctgggg ccctccaggt
2281 aggcccgttt tcacgtggag catgggagcc acgacccttc ttaagacatg tatcactgta
2341 gagggaagga acagaggccc tgggcccttc ctatcagaag gacatggtga aggctgggaa
2401 cgtgaggaga ggcaatggcc acggcccatt ttggctgtag cacatggcac gttggctgtg
2461 tggccttggc ccacctgtga gtttaaagca aggctttaaa tgactttgga gagggtcaca
2521 aatcctaaaa gaagcattga agtgaggtgt catggattaa ttgacccctg tctatggaat
2581 tacatgtaaa acattatctt gtcactgtag tttggtttta tttgaaaacc tgacaaaaaa
2641 aaagttccag gtgtggaata tgggggttat ctgtacatcc tggggcatta aaaaaaaaaa
2701 aaaa
//