LOCUS BC017715 2745 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens mitogen-activated protein kinase kinase kinase 7, mRNA
(cDNA clone MGC:21263 IMAGE:3906837), complete cds.
ACCESSION BC017715
VERSION BC017715.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2745)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2745)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC017715.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 22 Row: i Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21735561.
FEATURES Location/Qualifiers
source 1..2745
/db_xref="H-InvDB:HIT000038099"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21263 IMAGE:3906837"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2745
/gene="MAP3K7"
/gene_synonym="TGF1a"
/db_xref="GeneID:6885"
/db_xref="HGNC:HGNC:6859"
/db_xref="MIM:602614"
CDS 186..1925
/gene="MAP3K7"
/gene_synonym="TGF1a"
/codon_start=1
/product="mitogen-activated protein kinase kinase kinase
7"
/protein_id="AAH17715.1"
/db_xref="GeneID:6885"
/db_xref="HGNC:HGNC:6859"
/db_xref="MIM:602614"
/translation="MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGR
GAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCL
VMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPP
NLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGII
LWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPS
MEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTN
MEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADM
SEIEARIAATTGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPTR
SHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMK
VQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLE
VIRSQQQKRQGTS"
BASE COUNT 818 a 563 c 640 g 724 t
ORIGIN
1 cggacgcgtg gggagccaga gccggacacg gctgtggccg ctgcctctac ccccgccacg
61 gatcgccggg tagtaggact gcgcggctcc aggctgaggg tcggtccgga ggcgggtggg
121 cgcgggtctc acccggattg tccgggtggc accgttcccg gccccaccgg gcgccgcgag
181 ggatcatgtc tacagcctct gccgcctcct cctcctcctc gtcttcggcc ggtgagatga
241 tcgaagcccc ttcccaggtc ctcaactttg aagagatcga ctacaaggag atcgaggtgg
301 aagaggttgt tggaagagga gcctttggag ttgtttgcaa agctaagtgg agagcaaaag
361 atgttgctat taaacaaata gaaagtgaat ctgagaggaa agcgtttatt gtagagcttc
421 ggcagttatc ccgtgtgaac catcctaata ttgtaaagct ttatggagcc tgcttgaatc
481 cagtgtgtct tgtgatggaa tatgctgaag ggggctcttt atataatgtg ctgcatggtg
541 ctgaaccatt gccatattat actgctgccc acgcaatgag ttggtgttta cagtgttccc
601 aaggagtggc ttatcttcac agcatgcaac ccaaagcgct aattcacagg gacctgaaac
661 caccaaactt actgctggtt gcagggggga cagttctaaa aatttgtgat tttggtacag
721 cctgtgacat tcagacacac atgaccaata acaaggggag tgctgcttgg atggcacctg
781 aagtttttga aggtagtaat tacagtgaaa aatgtgacgt cttcagctgg ggtattattc
841 tttgggaagt gataacgcgt cggaaaccct ttgatgagat tggtggccca gctttccgaa
901 tcatgtgggc tgttcataat ggtactcgac caccactgat aaaaaattta cctaagccca
961 ttgagagcct gatgactcgt tgttggtcta aagatccttc ccagcgccct tcaatggagg
1021 aaattgtgaa aataatgact cacttgatgc ggtactttcc aggagcagat gagccattac
1081 agtatccttg tcagtattca gatgaaggac agagcaactc tgccaccagt acaggctcat
1141 tcatggacat tgcttctaca aatacgagta acaaaagtga cactaatatg gagcaagttc
1201 ctgccacaaa tgatactatt aagcgcttag aatcaaaatt gttgaaaaat caggcaaagc
1261 aacagagtga atctggacgt ttaagcttgg gagcctcccg tgggagcagt gtggagagct
1321 tgcccccaac ctctgagggc aagaggatga gtgctgacat gtctgaaata gaagctagga
1381 tcgccgcaac cacaggcaac ggacagccaa gacgtagatc catccaagac ttgactgtaa
1441 ctggaacaga acctggtcag gtgagcagta ggtcatccag tcccagtgtc agaatgatta
1501 ctacctcagg accaacctca gaaaagccaa ctcgaagtca tccatggacc cctgatgatt
1561 ccacagatac caatggatca gataactcca tcccaatggc ttatcttaca ctggatcacc
1621 aactacagcc tctagcaccg tgcccaaact ccaaagaatc tatggcagtg tttgaacagc
1681 attgtaaaat ggcacaagaa tatatgaaag ttcaaacaga aattgcattg ttattacaga
1741 gaaagcaaga actagttgca gaactggacc aggatgaaaa ggaccagcaa aatacatctc
1801 gcctggtaca ggaacataaa aagcttttag atgaaaacaa aagcctttct acttactacc
1861 agcaatgcaa aaaacaacta gaggtcatca gaagtcagca gcagaaacga caaggcactt
1921 catgattctc tgggaccgtt acattttgaa atatgcaaag aaagactttt ttttaaggaa
1981 aggaaaacct tataatgacg attcatgagt gttagctttt tggcgtgttc tgaatgccaa
2041 ctgcctatat ttgctgcatt tttttcattg tttattttcc ttttctcatg gtggacatac
2101 aattttactg tttcattgca taacatggta gcatctgtga cttgaatgag cagcactttg
2161 caacttcaaa acagatgcag tgaactgtgg ctgtatatgc atgctcattg tgtgaaggct
2221 agcctaacag aacaggaggt atcaaactag ctgctatgtg caaacagcgt ccattttttc
2281 atattagagg tggaacctca agaatgactt tattcttgta tctcatctca aaatattaat
2341 aatttttttc ccaaaagatg gtatatacca agttaaagac agggtattat aaatttagag
2401 tgattggtgg tatattacgg aaatacggaa cctttaggga tagttccgtg taagggcttt
2461 gatgccagca tccttggatc agtactgaac tcagttccat ccgtaaaata tgtaaaggta
2521 agtggcagct gctctattta atgaaagcag ttttaccgga ttttgttaga ctaaaatttg
2581 attgtgatac attgaacaaa atggaactca ttttttttta aggagtaaag atttttaatt
2641 ctgtgattgt gtgtatgtgt gttgaaactg taaagctttt atgactctaa tattaatctc
2701 ttaaatgaaa ttaaaaggca aaagaacatg aaaaaaaaaa aaaaa
//