LOCUS AJ583695 3222 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for B7-H3 protein.
ACCESSION AJ583695
VERSION AJ583695.1
KEYWORDS B7-H3 gene; B7-H3 protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3222)
AUTHORS Steinberger P.
JOURNAL Submitted (26-SEP-2003) to the INSDC. Steinberger P., Institute of
Immunology, University of Vienna, Borschkegasse 8a, Vienna, A-1090,
AUSTRIA.
REFERENCE 2
AUTHORS Steinberger P., Majdic O., Derdak S.V., Pfistershammer K.,
Kirchberger S., Klauser C., Zlabinger G., Pickl W.F., Stoeckl J.,
Knapp W.
TITLE Molecular characterization of human 4-Ig-B7-H3, a member of the B7
family with four immunoglobulin-like domains
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..3222
/db_xref="H-InvDB:HIT000249150"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_type="monocyte-derived dendritic cells"
/db_xref="taxon:9606"
CDS 44..1648
/gene="B7-H3"
/product="B7-H3 protein"
/db_xref="GOA:Q5ZPR3"
/db_xref="H-InvDB:HIT000249150.14"
/db_xref="HGNC:HGNC:19137"
/db_xref="InterPro:IPR003597"
/db_xref="InterPro:IPR003598"
/db_xref="InterPro:IPR003599"
/db_xref="InterPro:IPR007110"
/db_xref="InterPro:IPR013106"
/db_xref="InterPro:IPR013783"
/db_xref="InterPro:IPR036179"
/db_xref="UniProtKB/Swiss-Prot:Q5ZPR3"
/protein_id="CAE47548.1"
/translation="MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGT
DATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQ
GNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDT
VTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTY
SCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGF
SLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVAD
EGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEA
EVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAH
GSVTITGQPMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDG
EGEGSKTALQPLKHSDSKEDDGQEIA"
misc_feature 122..463
/gene="B7-H3"
/note="IgV-like domain"
misc_feature 464..775
/gene="B7-H3"
/note="IgC-like domain"
misc_feature 776..1117
/gene="B7-H3"
/note="IgV-like domain"
misc_feature 1118..1426
/gene="B7-H3"
/note="IgC-like domain"
BASE COUNT 635 a 1005 c 902 g 677 t
ORIGIN
1 cttccaccac ggggagccca gctgtcagcc gcctcacagg aagatgctgc gtcggcgggg
61 cagccctggc atgggtgtgc atgtgggtgc agccctggga gcactgtggt tctgcctcac
121 aggagccctg gaggtccagg tccctgaaga cccagtggtg gcactggtgg gcaccgatgc
181 caccctgtgc tgctccttct cccccgagcc tggcttcagc ctggcacagc tcaacctcat
241 ctggcagctg acagatacca aacagctggt gcacagcttt gctgagggcc aggaccaggg
301 cagcgcctat gccaaccgca cggccctctt cccggacctg ctggcacagg gcaacgcatc
361 cctgaggctg cagcgcgtgc gtgtggcgga cgagggcagc ttcacctgct tcgtgagcat
421 ccgggatttc ggcagcgctg ccgtcagcct gcaggtggcc gctccctact cgaagcccag
481 catgaccctg gagcccaaca aggacctgcg gccaggggac acggtgacca tcacgtgctc
541 cagctaccag ggctaccctg aggctgaggt gttctggcag gatgggcagg gtgtgcccct
601 gactggcaac gtgaccacgt cgcagatggc caacgagcag ggcttgtttg atgtgcacag
661 catcctgcgg gtggtgctgg gtgcaaatgg cacctacagc tgcctggtgc gcaaccccgt
721 gctgcagcag gatgcgcaca gctctgtcac catcacaccc cagagaagcc ccacaggagc
781 cgtggaggtc caggtccctg aggacccggt ggtggcccta gtgggcaccg atgccaccct
841 gcgctgctcc ttctcccccg agcctggctt cagcctggca cagctcaacc tcatctggca
901 gctgacagac accaaacagc tggtgcacag tttcaccgaa ggccgggacc agggcagcgc
961 ctatgccaac cgcacggccc tcttcccgga cctgctggca caaggcaatg catccctgag
1021 gctgcagcgc gtgcgtgtgg cggacgaggg cagcttcacc tgcttcgtga gcatccggga
1081 tttcggcagc gctgccgtca gcctgcaggt ggccgctccc tactcgaagc ccagcatgac
1141 cctggagccc aacaaggacc tgcggccagg ggacacggtg accatcacgt gctccagcta
1201 ccggggctac cctgaggctg aggtgttctg gcaggatggg cagggtgtgc ccctgactgg
1261 caacgtgacc acgtcgcaga tggccaacga gcagggcttg tttgatgtgc acagcgtcct
1321 gcgggtggtg ctgggtgcga atggcaccta cagctgcctg gtgcgcaacc ccgtgctgca
1381 gcaggatgcg cacggctctg tcaccatcac agggcagcct atgacattcc ccccagaggc
1441 cctgtgggtg accgtggggc tgtctgtctg tctcattgca ctgctggtgg ccctggcttt
1501 cgtgtgctgg agaaagatca aacagagctg tgaggaggag aatgcaggag ctgaggacca
1561 ggatggggag ggagaaggct ccaagacagc cctgcagcct ctgaaacact ctgacagcaa
1621 agaagatgat ggacaagaaa tagcctgacc atgaggacca gggagctgct acccctccct
1681 acagctccta ccctctggct gcaatggggc tgcactgtga gccctgcccc caacagatgc
1741 atcctgctct gacaggtggg ctccttctcc aaaggatgcg gtacacagac cactgtgcag
1801 ccttatttct ccaatggaca tgattcccaa gtcatcctgc tgcctttttt cttatagaca
1861 caatgaacag accacccaca accttagttc tctaagtcat cctgcctgct gccttatttc
1921 acagtacata catttcttag ggacacagta cactgaccac atcaccaccc tcttcttcca
1981 gtgctgcgtg gaccatctgg ctgccttttt tctccaaaag atgcaatatt cagactgact
2041 gaccccctgc cttatttcac caaagacacg atgcatagtc accccggcct tgtttctcca
2101 atggccgtga tacactagtg atcatgttca gccctgcttc cacctgcata gaatcttttc
2161 ttctcagaca gggacagtgc ggcctcaaca tctcctggag tctagaagct gtttcctttc
2221 ccctccttcc tcctcttgct ctagccttaa tactggcctt ttccctccct gccccaagtg
2281 aagacagggc actctgcgcc caccacatgc acagctgtgc atggagacct gcaggtgcac
2341 gtgctggaac acgtgtggtt cccccctggc ccagcctcct ctgcagtgcc cctctcccct
2401 gcccatcctc cccacggaag catgtgctgg tcacactggt tctccagggg tctgtgatgg
2461 ggcccctggg ggtcagcttc tgtccctctg ccttctcacc tctttgttcc tttcttttca
2521 tgtatccatt cagttgatgt ttattgagca actacagatg tcagcactgt gttaggtgct
2581 gggggccctg cgtgggaaga taaagttcct ccctcaagga ctccccatcc agctgggaga
2641 cagacaacta actacactgc accctgcggt ttgcaggggg ctcctgcctg gctccctgct
2701 ccacacctcc tctgtggctc aaggcttcct ggatacctca cccccatccc acccataatt
2761 cttacccaga gcatggggtt ggggcggaaa cctggagaga gggacatagc ccctcgccac
2821 ggctagagaa tctggtggtg tccaaaatgt ctgtccaggt gtgggcaggt gggcaggcac
2881 caaggccctc tggacctttc atagcagcag aaaaggcaga gcctggggca gggcagggcc
2941 aggaatgctt tggggacacc gaggggactg cccccccacc cccaccatgg tgctattytg
3001 gggctggggc agtcttttcc tggcttgcct ctggccagct cctggcctct ggtagagtga
3061 gacttcagac gttytgatgc cttccggatg tcatctctcc ctgccccagg aatggaagat
3121 gtgaggactt ytaatttaaa tgtgggactc ggagggattt tgtaaactgg gggtatattt
3181 tggggaaaat aaatgtcttt gtaaaaaaaa aaaaaaaaaa aa
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