LOCUS AJ005578 2141 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo sapiens mRNA for 6-phosphofructo-2-kinase.
ACCESSION AJ005578
VERSION AJ005578.1
KEYWORDS 6-phosphofructo-2-kinase; heart isoform; pfkfb2 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2141)
AUTHORS Heine-Suner D.
JOURNAL Submitted (15-APR-1998) to the INSDC. Heine-Suner D., Inmunologia,
Centro de Investigaciones Biologicas, C/Velazquez 144, Madrid
28006, SPAIN.
REFERENCE 3
AUTHORS Heine-Suner D., Diaz-Guillen M.A., Lange A.J.,
Rodriguez de Cordoba S.
TITLE Sequence and structure of the human
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase heart isoform
gene (PFKFB2)
JOURNAL Eur. J. Biochem. 254(1), 103-110(1998).
PUBMED 9652401
FEATURES Location/Qualifiers
source 1..2141
/db_xref="H-InvDB:HIT000244037"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 87..1604
/gene="pfkfb2"
/product="6-phosphofructo-2-kinase"
/EC_number="2.7.1.105"
/db_xref="GOA:O60825"
/db_xref="H-InvDB:HIT000244037.12"
/db_xref="HGNC:HGNC:8873"
/db_xref="InterPro:IPR001345"
/db_xref="InterPro:IPR003094"
/db_xref="InterPro:IPR013078"
/db_xref="InterPro:IPR013079"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR029033"
/db_xref="PDB:5HTK"
/db_xref="UniProtKB/Swiss-Prot:O60825"
/experiment="experimental evidence, no additional details
recorded"
/protein_id="CAA06606.1"
/translation="MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMI
GLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIR
KQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDD
PDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKV
INVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSV
RGKQFAQALRKFLEEQEITDLKVWTSHVKRTIQTAESLGVPYEQWKILNEIDAGVCEE
MTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQLLEPVIMELERQGNVLVISHQ
AVMHCLLAYFLDKDADELPYLRCPLHTIFKLTPVTYGCKVETIKLNVEAVNTHRDKPT
NNFPKNQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSPLRAQDMQEGAD"
BASE COUNT 554 a 517 c 544 g 526 t
ORIGIN
1 tcggttcggt cgcgttacag ggcaggcgcc ggggccaagg cagggaggga tcttaggaga
61 gatcgtagga catctgaaga gctgccatgt ctggggcatc ttcctcagaa cagaacaaca
121 acagctatga aaccaaaacc ccaaatcttc gaatgtcaga gaagaaatgt tcatgggcct
181 cctacatgac caactccccg actctgatcg ttatgattgg tttgccagcc cggggtaaaa
241 cctacgtgtc caagaaacta acacgctacc tcaactggat tggagtcccc accaaagtgt
301 ttaatcttgg ggtgtatcgg cgtgaagcag tcaagtccta taagtcctac gacttctttc
361 ggcatgacaa tgaggaggcc atgaagatcc gcaaacagtg tgctctggtg gcgctggaag
421 atgttaaggc gtatctcact gaggagaatg gtcagattgc ggtgtttgat gccaccaata
481 caacccggga gaggagggac atgattttga actttgctga acagaattcc ttcaaggtat
541 tctttgtgga atccgtctgt gatgatcctg atgtcattgc tgccaatatt ctggaggtta
601 aggtatcaag ccctgactat cctgaaagga acagagagaa cgtgatggag gacttcctga
661 agagaattga atgctacaaa gttacctacc gacctcttga cccagacaac tatgacaagg
721 atctttcttt catcaaggtg ataaacgtgg gccagcgatt tttagtcaac agagtccagg
781 actacatcca gagcaagata gtctactacc tcatgaatat ccacgtccag cctcgcacca
841 tttacctttg ccggcatgga gaaagcgagt tcaatctctt ggggaagatt gggggtgact
901 ctggcctctc ggtgcgggga aagcagtttg cccaagctct aaggaaattt ctggaggaac
961 aggaaataac agacctcaaa gtgtggacaa gccatgtgaa gaggaccata cagactgctg
1021 aatctctcgg ggtgccctat gagcagtgga agattctgaa tgagattgat gctggtgtgt
1081 gtgaagagat gacctatgca gagattgaga aacggtaccc agaagagttt gcacttcgag
1141 atcaagagaa gtatctgtat cgatatcctg gtggggagtc ataccaggac ctggtgcagc
1201 tgctggagcc tgtcatcatg gagctggaac gtcagggcaa tgtcctcgtc atctcccacc
1261 aggctgtcat gcactgcctc ctggcctact tcttggataa ggacgcagat gagctaccat
1321 acttgagatg ccctctccat accatcttca aacttactcc tgtgacctat gggtgcaaag
1381 tggaaacaat taaacttaac gtggaggctg tgaacacgca ccgtgacaag ccaactaaca
1441 acttccccaa gaaccaaacc cctgtaagga tgagaaggaa cagctttacg cctctgtcca
1501 gttcgaatac aataaggcgt ccaagaaatt acagtgttgg gagccggccc ctcaagcccc
1561 tcagccctct ccgtgcccag gacatgcaag aaggggccga ctagccgaag acccaagtca
1621 gcattccggt ggtgtaactg tgtgtttccc tccagccctg gcctcctgcc cttgtcacta
1681 atcaccaagg agtcattaac ttcctccctc tatgcccacc cctgacactt caccatttat
1741 cttaacacag aacatgaggt tatgtgtgca aattgagtct tttaggacag attctcagat
1801 gggatgatct ggaggaggag gaaaaagata cacgcccttg gggctgagca tgccccacac
1861 tcttggatct tctctctgtt ccctggtgtc ttcactaatg tcctcatgtt ggtgaagtgt
1921 tgggggatgg agggcgggtg agcagtcggg ggacaaaaag tctatttttc cttcactttt
1981 gtctcttcaa tgtgtgtttt cctcacactc cttacttgac tgctttcttc ccccactttc
2041 atgtcccctc tggattgtcc agtgtaatgc atggcattgt ggtgtctgtc taggaaggaa
2101 ggggtgattg acaagagaca agtctggccc agttaatgct g
//