LOCUS AF289028 1572 bp mRNA linear HUM 04-DEC-2001
DEFINITION Homo sapiens transmembrane protein B7-H2 ICOS ligand mRNA, complete
cds.
ACCESSION AF289028
VERSION AF289028.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1572)
AUTHORS Wang,S., Zhu,G., Chapoval,A.I., Dong,H., Tamada,K., Ni,J. and
Chen,L.
TITLE Costimulation of T cells by B7-H2, a B7-like molecule that binds
ICOS
JOURNAL Blood 96 (8), 2808-2813 (2000)
PUBMED 11023515
REFERENCE 2 (bases 1 to 1572)
AUTHORS Wang,S., Zhu,G., Ni,J. and Chen,L.
TITLE Direct Submission
JOURNAL Submitted (23-JUL-2000) Immunology, Mayo Clinic, 200 First Street
SW, Rochester, MN 55905, USA
FEATURES Location/Qualifiers
source 1..1572
/db_xref="H-InvDB:HIT000076374"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 125..1033
/codon_start=1
/product="transmembrane protein B7-H2 ICOS ligand"
/protein_id="AAG01176.1"
/translation="MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSR
FDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFN
VTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTS
INGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIE
NVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWV
CRDRCLQHSYAGAWAVSPETELTGHV"
BASE COUNT 325 a 480 c 471 g 296 t
ORIGIN
1 gagtagagcc gatctcccgc gccccgaggt tgctcctctc cgaggtctcc cgcggcccaa
61 gttctccgcg ccccgaggtc tccgcgcccc gaggtctccg cggcccgagg tctccgcccg
121 caccatgcgg ctgggcagtc ctggactgct cttcctgctc ttcagcagcc ttcgagctga
181 tactcaggag aaggaagtca gagcgatggt aggcagcgac gtggagctca gctgcgcttg
241 ccctgaagga agccgttttg atttaaatga tgtttacgta tattggcaaa ccagtgagtc
301 gaaaaccgtg gtgacctacc acatcccaca gaacagctcc ttggaaaacg tggacagccg
361 ctaccggaac cgagccctga tgtcaccggc cggcatgctg cggggcgact tctccctgcg
421 cttgttcaac gtcacccccc aggacgagca gaagtttcac tgcctggtgt tgagccaatc
481 cctgggattc caggaggttt tgagcgttga ggttacactg catgtggcag caaacttcag
541 cgtgcccgtc gtcagcgccc cccacagccc ctcccaggat gagctcacct tcacgtgtac
601 atccataaac ggctacccca ggcccaacgt gtactggatc aataagacgg acaacagcct
661 gctggaccag gctctgcaga atgacaccgt cttcttgaac atgcggggct tgtatgacgt
721 ggtcagcgtg ctgaggatcg cacggacccc cagcgtgaac attggctgct gcatagagaa
781 cgtgcttctg cagcagaacc tgactgtcgg cagccagaca ggaaatgaca tcggagagag
841 agacaagatc acagagaatc cagtcagtac cggcgagaaa aacgcggcca cgtggagcat
901 cctggctgtc ctgtgcctgc ttgtggtcgt ggcggtggcc ataggctggg tgtgcaggga
961 ccgatgcctc caacacagct atgcaggtgc ctgggctgtg agtccggaga cagagctcac
1021 tggccacgtt tgaccggagc tcaccgccca gagcgtggac agggcttcca tgagacgcca
1081 ccgtgagagg ccaggtggca gcttgagcat ggactcccag actgcagggg agcacttggg
1141 gcagccccca gaaggaccac tgctggatcc cagggagaac ctgctggcgt tggctgtgat
1201 cctggaatga ggccctttca aaagcgtcat ccacaccaaa ggcaaatgtc cccaagtgag
1261 tgggctcccc gctgtcactg ccagtcaccc acaggaaggg actggtgatg ggctgtctct
1321 acccggagcg tgcgggattc agcaccaggc tcttcccagt accccagacc cactgtgggt
1381 cttcccgtgg gatgcgggat cctgagaccg aagggtgttt ggtttaaaaa gaagactggg
1441 cgtccgctct tccaggacgg cctctgtgct gctggggtca cgcgaggctg tttgcagggg
1501 acacggtcac aggagctctt ctgccctgaa cgcttccaac ctgctccggc cggaagccac
1561 aggacccact ca
//