LOCUS AF257230 1232 bp mRNA linear ROD 14-MAY-2000
DEFINITION Mus musculus CCLP precursor (CCLP) mRNA, complete cds.
ACCESSION AF257230
VERSION AF257230.1
KEYWORDS .
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 1232)
AUTHORS Wu,D., Giannoni,M.A., Kiesecker,C.L., Faas,S.J., Mickle,A.P.,
Matis,L.A. and Rother,R.P.
TITLE CCLP, A novel molecule that regulates T cell activation
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1232)
AUTHORS Wu,D., Giannoni,M.A., Kiesecker,C.L., Faas,S.J., Mickle,A.P.,
Matis,L.A. and Rother,R.P.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2000) Molecular Development, Alexion
Pharmaceuticals Inc., 25 Science Park, Suite 360, P.O. Box 15, New
Haven, CT 06514, USA
FEATURES Location/Qualifiers
source 1..1232
/organism="Mus musculus"
/mol_type="mRNA"
/strain="BALB/c"
/db_xref="taxon:10090"
/sex="male"
/tissue_type="spleen"
gene 1..1232
/gene="CCLP"
CDS 31..633
/gene="CCLP"
/note="CD28 and CTLA-4 like protein"
/codon_start=1
/product="CCLP precursor"
/protein_id="AAF70099.1"
/translation="MKPYFCHVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKY
PETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSS
QGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWLPVGCAAFVVVLLFGCI
LIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKKSRLAGVTS"
sig_peptide 31..93
/gene="CCLP"
mat_peptide 94..630
/gene="CCLP"
/product="CCLP"
misc_feature 94..453
/gene="CCLP"
/note="Region: extracellular domain"
misc_feature 454..522
/gene="CCLP"
/note="Region: transmembrane domain"
misc_feature 523..630
/gene="CCLP"
/note="Region: cytoplasmic domain"
BASE COUNT 340 a 296 c 249 g 347 t
ORIGIN
1 gggagaagac tgcaactgct cctggcagac atgaagccgt acttctgcca tgtctttgtc
61 ttctgcttcc taatcagact tttaacagga gaaatcaatg gctcggccga tcataggatg
121 ttttcatttc acaatggagg tgtacagatt tcttgtaaat accctgagac tgtccagcag
181 ttaaaaatgc gattgttcag agagagagaa gtcctctgcg aactcaccaa gaccaaggga
241 agcggaaatg cggtgtccat caagaatcca atgctctgtc tatatcatct gtcaaacaac
301 agcgtctctt ttttcctaaa caacccagac agctcccagg gaagctatta cttctgcagc
361 ctgtccattt ttgacccacc tccttttcaa gaaaggaacc ttagtggagg atatttgcat
421 atttatgaat cccagctctg ctgccagctg aagctctggc tacccgtagg gtgtgcagct
481 ttcgttgtgg tactcctttt tggatgcata cttatcatct ggttttcaaa aaagaaatac
541 ggatccagtg tgcatgaccc taatagtgaa tacatgttca tggcggcagt caacacaaac
601 aaaaagtcta gacttgcagg tgtgacctca taagctggaa cacccggacc cacaggagga
661 aacgcatggc taagttcccc tgaaacttga atggagaaat tcttctattt ttgtggacca
721 cagggcacct gacttgattt aactacagac aacattctgc tggtgttttg tttgtctgga
781 tcagtgacca tcagtcattc agaatttcag cagactgccc tgggtttgct gagtcctttt
841 aagatgaacc ccttcttaag gaagacccag ctcatatata ttcaacaaac agacctcact
901 gggatagaat gcccctctct ccgtgcctga ttctagctat gcactggcca ggaaaacaaa
961 catatctcca gcattttttt acaaaaaatg ccaagggtat gaatctgtaa agcacacagg
1021 cagccaatgg ccaccatctg tcctcatttt tcagattcca ttttctttcc atggagatca
1081 gcattctttc tagaatcaga cagtagaggg agatgcttca caacagaagc gcctgtgttt
1141 ctgcgatttt gatgtatata ctttatcgaa ctcatgcatt agaaccaaca tgctctcttc
1201 caattcctag actctagctg atcactgctt ca
//