LOCUS AH009974 10723 bp DNA linear HUM 28-JUL-2016
DEFINITION Homo sapiens FcRn alpha chain (FCGRT) gene, complete cds.
ACCESSION AH009974 AF200219 AF200220
VERSION AH009974.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10723)
AUTHORS Mikulska,J.E., Pablo,L., Canel,J. and Simister,N.E.
TITLE Cloning and analysis of the gene encoding the human neonatal Fc
receptor
JOURNAL Eur. J. Immunogenetics 27, 231-240 (2000)
REFERENCE 2 (bases 1 to 10723)
AUTHORS Simister,N.E., Mikulska,J.E., Pablo,L. and Canel,J.
TITLE Direct Submission
JOURNAL Submitted (29-OCT-1999) Rosenstiel Center for Basic Biomedical
Sciences, W.M. Keck Institute for Cellular Visualization and
Biology Department, Brandeis University, 415 South Street, MS 029,
Waltham, MA 02254-9110, USA
COMMENT On or before Apr 6, 2016 this sequence version replaced AF200219.1,
AF200220.1, AH009974.1.
FEATURES Location/Qualifiers
source 1..10723
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
repeat_region complement(111..403)
/rpt_family="Alu"
gene 661..10580
/gene="FCGRT"
mRNA join(661..878,1515..1601,2009..2251,2329..2604,8757..9026,
9706..9822,10258..10580)
/gene="FCGRT"
/product="FcRn alpha chain"
exon 661..878
/gene="FCGRT"
/number=1
repeat_region complement(899..1266)
/rpt_family="MSR1"
exon 1515..1601
/gene="FCGRT"
/number=2
CDS join(1529..1601,2009..2251,2329..2604,8757..9026,
9706..9822,10258..10367)
/gene="FCGRT"
/codon_start=1
/product="FcRn alpha chain"
/protein_id="AAG31421.1"
/translation="MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGT
PAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAL
GGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQR
WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTC
SAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQH
AGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRG
DDTGVLLPTPGEAQDADLKDVNVIPATA"
exon 2009..2251
/gene="FCGRT"
/number=3
exon 2329..2604
/gene="FCGRT"
/number=4
repeat_region complement(2810..3087)
/rpt_family="Alu"
repeat_region complement(3114..3830)
/rpt_family="Alu"
repeat_region complement(4368..4964)
/rpt_family="Alu"
repeat_region 5036..5589
/gene="FCGRT"
/rpt_family="Alu"
gap 5761..5860
/estimated_length=unknown
repeat_region complement(5924..6203)
/rpt_family="Alu"
repeat_region complement(6327..6618)
/rpt_family="Alu"
repeat_region complement(6691..6975)
/rpt_family="Alu"
repeat_region complement(7031..7324)
/rpt_family="Alu"
repeat_region 7524..7830
/gene="FCGRT"
/rpt_family="Alu"
repeat_region 7841..8126
/gene="FCGRT"
/rpt_family="Alu"
repeat_region complement(8270..8545)
/rpt_family="Alu"
exon 8757..9026
/gene="FCGRT"
/number=5
exon 9706..9822
/gene="FCGRT"
/number=6
exon 10258..10580
/gene="FCGRT"
/number=7
BASE COUNT 2165 a 2924 c 2937 g 2597 t
ORIGIN
1 aagctttgta gcaggagtgt gggcgggggc tggtgcctgg aggggccttc gagtgaggca
61 gcattgtatg gggaccatgt ggtcactgaa gtcctagcag aaggatgtgg tttttttttt
121 tttttgagac ggagtctcgc tctgttgcca gtctggagtg cagtggtgca atctcggctc
181 actgcgacct ccacctcccg ggttcaagca attctcctgt ctcagcctcc cgagtagctg
241 ggaccacagg cccaccacca cgctcagcta atttttgtat tattagtaga gacgggggtg
301 tcaccatatt ggccaggctg gtctcgaact cctgacctcg tgatccgccc gccttggcct
361 cccaaagtgc tgggattaca ggcgtgagtc actgcgcccg gcccgcagaa ggatattaaa
421 gagcacctgc aggaattttt taaggggatg ccgggggaag ggcttgaagg aggaactaag
481 gaggcttcca gaagattttg attaacagcg agcgctaggg aaggccacgg ggatacagag
541 gggtaggagg aggatccaga gacctccaag ttgtggactc cggaggatcg agttcctttc
601 ccagttttgt caagaattcc ctgagcggca gacaccctca aagtaaaaaa cgggaaccac
661 agagaaggaa aaagaagaac cacaagcgtt ttgagaaaca aacaggctgg gcctagggct
721 ggggtgtgcc ctgcaactgg ggggtggggc tggatgttct tggagtcagg gagcagcagc
781 ctcccacagg atgtgagaga ggaactgggg tctccagttc acgggagcca ggagccggcc
841 agggccgcag gcaggaaggg agcgaggctg aagggaacgt gagccgacca gggcccgact
901 gagggaggag gggctggggg cctggaaccc tgggtctgag ggaggagtgg ctgggggtct
961 cgacactggg tctgagggag gaggggtggg ggcctggatt cctgggtctg agagaggagg
1021 gactgggggt ctggacgctg ggtctgaggg aggagggagg aggggccggg ggggcctgga
1081 ctcctgggtc cgagggagga ggggttgggg gcccggactc ctgggtccga gggtagagcg
1141 gttgggggcc cggactcctg ggtccgaggg tagagcggtt gggggcccgg actcctgggt
1201 ccgagggaag agcggttggg ggcctggact ccggggtctg agggaggagg ggctggggcc
1261 tgaggggggc ggaaggggcg tggcggagct cggggccggg actctcagcc tatcaagtgt
1321 ctgtaattaa ttaaccaact gagatccagt tcaggggtga aagttcttca ggtacgagga
1381 gggcattgtt gtcagtctgg accgagcccg cagagcccct cctcggcgtc ctggtcccgg
1441 ccgtgcccgc ggtgtcccgg gaggaagggg cgggccgggg gtcgggagga gtcacgtgcc
1501 ccctcccgcc ccaggtcgtc ctctcagcat gggggtcccg cggcctcagc cctgggcgct
1561 ggggctcctg ctctttctcc ttcctgggag cctgggcgca ggtgagggcc gctccgggcc
1621 agggcctgct gcaggcgggc ggcgggaggc ggccccaggc aggcaggggc gaagccagcg
1681 ggacccgagt tccccgcgag cccctggcgc tgccttctcc gctcaattaa ctttctcaac
1741 gtctcctgct gggcctgagg ctgggaacca cctgtcgcct cttgtgtctg tttccctctc
1801 tctctctggg tctctgtccc cctctctttc tgggtctctt gtctctctct ctctgggtct
1861 ctgtcccccc ccccccgggt ttctgtcccc tctctctgaa tctgtccccc tccctccata
1921 atagattctt ctccctccct gggtatctgt cccactgcag tctagttccc cgcccgtgtg
1981 ctcccttcag ctctgtttct gtctgcagaa agccacctct ccctcctgta ccaccttacc
2041 gcggtgtcct cgcctgcccc ggggactcct gccttctggg tgtccggctg gctgggcccg
2101 cagcagtacc tgagctacaa tagcctgcgg ggcgaggcgg agccgtgtgg agcttgggtc
2161 tgggaaaacc aggtgtcctg gtattgggag aaagagacca cagatctgag gatcaaggag
2221 aagctctttc tggaagcttt ggggggaaaa ggtgagattc cggtctggag gggcaagggg
2281 ccgggtccat gctccggggc cccgcttacc tgtgtttggg cgccccaggt ccctacactc
2341 tgcagggcct gctgggctgt gaactgggcc ctgacaacac ctcggtgccc accgccaagt
2401 tcgccctgaa cggcgaggag ttcatgaatt tcgacctcaa gcagggcacc tggggtgggg
2461 actggcccga ggccctggct atcagtcagc ggtggcagca gcaggacaag gcggccaaca
2521 aggagctcac cttcctgcta ttctcctgcc cgcaccgcct gcgggagcac ctggagaggg
2581 gccgcggaaa cctggagtgg aagggtgagc cggatctgca gccgcagctg ttctgtcctc
2641 tctcccgtca tgcccacctg cctcagttcc cctgccagga ccctccatca gcctcccact
2701 gcagcccacg ctctgccccc ccattcctca ggggtccttc tacactcagc cctcccatgg
2761 ctccccagcg ccccccagga caaactcctg gcttccttcc ttgccttctt tttttttttt
2821 tttttgtgag acggagtttc gctcttgttg cccaggctgg agtgtaatgg cgcgatctcg
2881 gctcaccaca acctccgcct cccgggttca agtgatctcc tgcctcagcc tcccgagtgg
2941 ctgggattac aggcatgcac caccatgccc ggctaatttt gtattttagt agagacgggg
3001 tttcttcatg ttggtcaggc tggtctcaaa cccctgacct caggtgatcc gcccacctca
3061 gcctcccaaa gtgctgggat tacaggcatg agctactgct cctggctccc cccttttttt
3121 tttttttgag acagattctc gctctgtcac cccaggctgg aatgtggtgg caccatctcg
3181 gctcactgca gcctgaacct cccaggctca agcagtcctc ccacctcagc caaccaagta
3241 gctgggacca cagccagcat catcacacct ggctaacttt atattttgta gacacggtgt
3301 ctcactatgt tgcccaggct ggtcttgaac tcctaggctc cagcgattct cctgctttgg
3361 tctcctgagt agctgagatt acaggtgcat accaccataa ctggctaatt tttttttttc
3421 cgcacaatct ctgttgccca ggctagtgtg aaggagggtg atctcagctc gctgcaacct
3481 ccgcctcctg ggtttaaggg attccgctgc ttcagcctca tgagtagctg gcactatagg
3541 cacatccacc atgtctggct aatttttata cttttagtag agatggggtt tcgtcatggt
3601 agctaggctg gtctcaaact cttgacctca agtgatccac ccacctccgc ctcccaaagt
3661 gctgggatta caggagtgag ctaccgcgtc tggccatacc tggctaattt ttaaaatttg
3721 ttgtagaggt ggcatctcac tatgctgccc aggccagact caaactcctg gcctcaagtg
3781 attctctcac tttggcctcc cagggtgctg ggatgacagg tgtgagccac tgtgcttggc
3841 cttccttgcc ttaatgtcct catcagaccc acgcagcagc acttgtctct acgcagccat
3901 cagagtctac gctccagcca cccaacataa gcaatctcct ccctctgggc atttgctcat
3961 ccagtttccc ctggcacctc tctgttccac ccttccccct ctctgcatat actccagccc
4021 tccttattct tcaaggtcag ggctggatat cacttcctct gagaagcctt tcctcagctc
4081 tgtagggcag agttcactgt ttcctccccg gaggccccca gatccccact cattcaactg
4141 ttggccaaga gcatttgcac tgccaggcgc tgctctgggc cttgagcaaa gagggaagtg
4201 acacacattc accctctgtg gctcccaggc tgctggacaa agatagatcc cagctgggga
4261 tgtgcacaga tattcattcc aagtgccaca aaggagaagt tgagactcaa ccaggtagtt
4321 tttctttaat tgtcttcttt ctttcctaag tagggaaaat ttctttcttt ttttgagaca
4381 gagttttgct cttgtcgccc atggctggag tgcaagtggc ggcgatctcg gctaactgca
4441 acctccgcct cccaggttca agtgattctc ctgcactcag cctcccgagt agctgggact
4501 cacagcgttg caccaccacg cctggctaat ttttgtttgt tttttttttt ttagtaaaga
4561 cagggtttta ccatgttggc cgggatggtc tcgatctttt tacctcgtga tctgcctgcc
4621 tcggcctccc aaagtgctga attacagacg tagccactgc tcctggcctt tgttgttgtt
4681 gttgttgttt ttgagacaga ctcttgcact gtcgcccaga ctgcagtact gtggcgcaat
4741 cttggcttca ctgcaacctc cgcctcccag gttcaagcaa ttctcctacc tcagcctccc
4801 gagtagctgg gattacaggc acacaccacc atgcctggct aatttttgta tttttagtag
4861 agacgggggc ttcaccatgc tggccaggct ggtctcgaac tcctgatctc gtgatctgcc
4921 taccttggcc tcccaaagtg ctgggattac aggcatgagc caccactcct ggcttaagga
4981 gggaaagttt caaaccacac ttaagtagaa acaatagtat aaaacggacc agacacggtg
5041 gctcacgcct ataatcccag aactttggga ggccgaggca ggtggattgc ttgatcccag
5101 gagttcaaga ccgcatctct actaaaaact caaaaaatta gcctggcatg gtggtatgtg
5161 cctctagtcc cagccactgg ggaggctatg gcaggaggat cgcttgagct caggagtttg
5221 aggctgtagt gaactgattg caactctgca ctccagccca gatgacagag ccagaccctg
5281 tctcaaaaag aaaaaaaata tggtggccag gtgcagtggc tcacgcctgt aattccaaca
5341 ctttgggagg ccgaggtggg cagatcactt aaggtcagga gtttgagata agcctggcca
5401 acagagtgaa accccatctc tactaaacat acaaaaatta gccgggtgcg gtggtgggtg
5461 cttgtaattc cagctattcg ggaggctgag gcaggagaat cacttgatcc cgggaagcag
5521 aggttgcagt gagccgagat caagccactg cactccagcc tgggcaacaa agcaagactc
5581 tgtctcaaag aaagaaggaa agaaagagag aggagaggga gagagaaaga ggaaggaaag
5641 gaaggaagga aggaaggaag cgagcatccc atcactgaga cttaataatt atcaacccat
5701 ggttttttga atttcacgca catcctcact cacttcccca ccccacttca catcaagctt
5761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
5821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ggatccttct gccttgacct
5881 cccaagtgct ggaattgcag gcatgagcca ttgcacccgg cttttttttt tttttttctt
5941 tgagacaggc acttgcactg ttgcctagac tggagtgcag tagcgggatt agagttcact
6001 gcagcctcaa cctcccaagc tcaagcgatc ctcccacctt acccttcctg aatggatggg
6061 gccacaggtg tgtaccatca cacgtagtta atttttaaac tttttcagag acggggtttc
6121 tccatgttgc ccaggctggt cttgaactcc cggcttccag tgatcctcct gcctcagctt
6181 cccaaagtgc tgggattaca ggcatgaacc actgcaccca accttttttc attcccttaa
6241 cgaaaccttt ggatgaacaa aaattcttaa tttcagtgaa gttcagttta tcgacttcaa
6301 tttatacatt ttataaagtt tatgaatttt tttttttttt tttagacgga gtcttgctct
6361 gtcgcccagg ctggagtgca gtggctatac ccaggtgtga tcataactca ctccagcctc
6421 aaactcctgg gctcaaggat tcctcctgcc tcagtctcca gagtaggtgg gaccacaggc
6481 acatccacca cactggctaa ttttttttat ttgtagtgga gactacgtct tactgtttgc
6541 ccaggctggt ctccaactcc tgggttcaag tgatccacct cattctccca aagcgctggg
6601 attgtaggag tgagccactg cacccagcct gtctgctaat attatgttta agagttctga
6661 atcttttttt aaatttttta aaatttttaa ttttttattt tttttgagac agtcttgctc
6721 tgtcgcccag gctggagtgc aatggtgcaa tcttggctca atgcaacctc cgccttctgg
6781 gttcaagcga ttctcctgcc ttagcctcct gagtagctgg gattacaggt acactccacc
6841 atgcctggct aatttttttg tatttttagt agagatggga tttcaccatg ttggtcaggc
6901 tggtctcgac ctcctgacct cgtgatcctc ctgcctccac cccccaaagc gccaggattc
6961 taggtgtgag ccaccacacc tgtcctgaat ctatatttat gagagacatt ggccttaagc
7021 tctctttttt tttttttttt tttttttttg agatggagtc tcgctctgtc acccaggctg
7081 gagtgcagtg gcgcaatctc ggctcactgc aagctccgcc tcccgggttc acgccattct
7141 cctgcctcag cctcccaagt ggctgggact acaggcgcgg ccaccacgcc cggctaattt
7201 tttgtatttt tagtagagat ggggtttcac cgtgttagcc gggatagtct caatctcctg
7261 acctcgtgat ccgcctgcct cggcctccca aagtgctggg attacaggcg tgagccaccg
7321 cgcctggcca agttctcttt cttataatgt gctttgttgt caagatgatg ctgacctcat
7381 aaaatatgct gggagagtgt ttcctctgtt ttatggcctg aagagttagt gtaggaatag
7441 aatcatttct acattggaag aattcactaa ttgatgtctt ctggacctgg aattttagtt
7501 tttggaaagt tttaaactat gattaaaaat tttaaatagg ccgggtgtgg tgcatcatgc
7561 ctgtaatccc agcactttgg gaggctgagg caggtagatc acaatgtcag gaatttgaga
7621 ccagcctggc caatatggtg aaacaccgtc tctactaaaa ataaaaaaat tacccggcat
7681 ggtggtgcat gcacctgtag tcccagccac tcgggaggct gtggaagaag aaactcttga
7741 acccaggaag tgggggttgc agtgagtcga gatcgtgcca ctgcactcca gcctgggtga
7801 cagagcgaga ctcttatctc aaaaacaaaa ggctaggcgt ggtggctcac acctgtaatc
7861 ccaacacttt ggaggcccag gcggatggat catgaggtca ggagattgag accatcctgg
7921 ctaagacggt gaaaccccgt ctctactaaa aatacaaaaa attagccaag tgtggtggtg
7981 ggcacctata gtcccagcta ctcaggaggc tgaggcagga gaatggcgtg aacccaggag
8041 gcggagcttg cagtgagccg agatcgcgcc actgcactcc agcctgggag acagagcaag
8101 attccatctc aaaaaaaaaa aaaaaattta aatagttata ggactacaga cgttttaaat
8161 ttcctcttgt gtcagtttag aaggttgtat ttatcaggaa tgtgttcagt tcatctaaat
8221 tttcaaatgt gttgctgtgg aatttttcat aattatcctc tatctttttt tttttttctt
8281 tttttctgag acggggtctc actctgtcgc ccaggctgga gtgcagtggc acgatcctgg
8341 ctcactgcaa catctgcctc ccaggttcaa gcaattctcc tgcctcagcc tcctgagtag
8401 ctgggactac aggtgcccgg ctaatttttg tatttttagt agagatgggg tttcaccatg
8461 ttggccagtg tggtctcgaa ctcctgacct caggtgatcc acccactttg gcctcccaaa
8521 gtgttgcgat tacaggcgtg agccaacatg cccagcccaa ggaggtgaca tcttgagggg
8581 acaccttcgg ggtggacagt tgagtctctg tcacctagga agtgcctccc cttttaccac
8641 tgtattatct gcggttagca cagtgcaaac atggaggcct ctttctgtcc ctatccagcc
8701 ctggctctgg gagtggtggg ctcgcgactt aggcctgtct gcctgatttc ctgcagagcc
8761 cccctccatg cgcctgaagg cccgacccag cagccctggc ttttccgtgc ttacctgcag
8821 cgccttctcc ttctaccctc cggagctgca acttcggttc ctgcggaatg ggctggccgc
8881 tggcaccggc cagggtgact tcggccccaa cagtgacgga tccttccacg cctcgtcgtc
8941 actaacagtc aaaagtggcg atgagcacca ctactgctgc attgtgcagc acgcggggct
9001 ggcgcagccc ctcagggtgg agctgggtga ggtcccgcca ggtggtgatg ctcctggttt
9061 cccgttgcct tgtctcactg ctgcgccggt ccttcctgag tctgaccttc ctccccactg
9121 ctgccacctc cttgaatctg actgccttga acctcacgcc tgtcagtgcc cccaaaacct
9181 gatggcttgt ccttcccaag gccaactgcc ttccgtctcc tgctgcttct ggcctcactg
9241 agtctgaaga gctgttaact accatggcca gtcctccctg agtctgacca tcttccatcc
9301 tgctgctgct gctgctgctg ctgcgggtct tcctggaatc tgaccattcg ttgtctgcta
9361 tgcccgtacc tcaccaagac tgactgcctg ctgctttgct actgcccggg cccatgagac
9421 tgacttccca ctgctctgcc tgcctctccc cactgcactg gcacagcccg ccttgccgct
9481 gctgatccat tgccggtgtg accgcggccg ctcgtgctgt agctggttct tacgtccaac
9541 ctgggggcag tctgccagat cgcctgcctg gcctcgcctc tgcccatcag acacttggtg
9601 ctggaatctc cgaggctggg agggactggg agcgccccag ttctgtgtcc tgactgggtg
9661 gggtggaggg gctgctccac atctcacagc gttctctggc tgcagaatct ccagccaagt
9721 cctccgtgct cgtggtggga atcgtcatcg gtgtcttgct actcacggca gcggctgtag
9781 gaggagctct gttgtggaga aggatgagga gtgggctgcc aggtgggggg cagcgggagg
9841 aagagcctct gagagaggga cagagacccc aagagagggg cacacagacc tgggaggaca
9901 gagacccaga gaggggggac agagatcaga gagaggtgga gacagaaacc cagagatggg
9961 agaacagagg tgcagagaga gggggacgga gacagagacc cagagacggg ggaacagaga
10021 cccagaggga cagagagagg tgcggacaga gggaggggga gacagaccca gaggagggag
10081 gcaaagatgt agaaagaggg gggacggaaa attgggagaa ggggagacaa aggcccagaa
10141 ggaaggggat agagactgag gaagagtgtg tgagacacac acacaaatgg gggacgccag
10201 tcagacccag agcgcctcag agattctgat gacctctccc tctctctctc tcctcagccc
10261 cttggatctc ccttcgtgga gacgacaccg gggtcctcct gcccacccca ggggaggccc
10321 aggatgctga tttgaaggat gtaaatgtga ttccagccac cgcctgacca tccgccattc
10381 cgactgctaa aagcgaatgt agtcaggccc ctttcatgct gtgagacctc ctggaacact
10441 ggcatctctg agcctccaga aggggttctg ggcctagttg tcctccctct ggagccccgt
10501 cctgtggtct gcctcagttt cccctcctaa tacatatggc tgttttccac ctcgataata
10561 taacacgagt ttgggcccga atcagtgtgt tctcatcatt tttcaggcag gggaggtaag
10621 ggaataagtc gggggactga atggcggctg ggcctcggat ctctcctaca ggtaacatgc
10681 tgccacaggg gaacctgcca gttttataca tcaggtcatg tat
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