LOCUS AF077301 1353 bp mRNA linear HUM 27-OCT-1998
DEFINITION Homo sapiens Bcl-2-interacting protein beclin mRNA, complete cds.
ACCESSION AF077301
VERSION AF077301.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1353)
AUTHORS Liang,X.H., Kleeman,L.K., Jiang,H.H., Gordon,G., Goldman,J.E.,
Berry,G., Herman,B. and Levine,B.
TITLE Protection against fatal Sindbis virus encephalitis by beclin, a
novel Bcl-2-interacting protein
JOURNAL J. Virol. 72 (11), 8586-8596 (1998)
PUBMED 9765397
REFERENCE 2 (bases 1 to 1353)
AUTHORS Levine,B., Liang,X.H. and Kleeman,L.
TITLE Direct Submission
JOURNAL Submitted (07-JUL-1998) Medicine, Columbia University College of
Physicians & Surgeons, 630 West 168th Street, New York, NY 10032,
USA
FEATURES Location/Qualifiers
source 1..1353
/db_xref="H-InvDB:HIT000066218"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21"
/tissue_type="normalized brain"
/dev_stage="infant"
CDS 1..1353
/function="antiviral protein"
/function="candidate tumor suppressor protein"
/note="coiled coil protein"
/codon_start=1
/product="Bcl-2-interacting protein beclin"
/protein_id="AAC68653.1"
/translation="MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTA
PLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGE
ASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQ
NYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAE
AERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHI
WHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYG
NHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCL
PYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
"
variation 308
/note="polymorphism"
/replace="t"
BASE COUNT 387 a 301 c 372 g 293 t
ORIGIN
1 atggaagggt ctaagacgtc caacaacagc accatgcagg tgagcttcgt gtgccagcgc
61 tgcagccagc ccctgaaact ggacacgagt ttcaagatcc tggaccgtgt caccatccag
121 gaactcacag ctccattact taccacagcc caggcgaaac caggagagac ccaggaggaa
181 gagactaact caggagagga gccatttatt gaaactcctc gccaggatgg tgtctctcgc
241 agattcatcc ccccagccag gatgatgtcc acagaaagtg ccaacagctt cactctgatt
301 ggggaggcat ctgatggcgg caccatggag aacctcagcc gaagactgaa ggtcactggg
361 gacctttttg acatcatgtc gggccagaca gatgtggatc acccactctg tgaggaatgc
421 acagatactc ttttagacca gctggacact cagctcaacg tcactgaaaa tgagtgtcag
481 aactacaaac gctgtttgga gatcttagag caaatgaatg aggatgacag tgaacagtta
541 cagatggagc taaaggagct ggcactagag gaggagaggc tgatccagga gctggaagac
601 gtggaaaaga accgcaagat agtggcagaa aatctcgaga aggtccaggc tgaggctgag
661 agactggatc aggaggaagc tcagtatcag agagaataca gtgaatttaa acgacagcag
721 ctggagctgg atgatgagct gaagagtgtt gaaaaccaga tgcgttatgc ccagacgcag
781 ctggataagc tgaagaaaac caacgtcttt aatgcaacct tccacatctg gcacagtgga
841 cagtttggca caatcaataa cttcaggctg ggtcgcctgc ccagtgttcc cgtggaatgg
901 aatgagatta atgctgcttg gggccagact gtgttgctgc tccatgctct ggccaataag
961 atgggtctga aatttcagag ataccgactt gttccttacg gaaaccattc atatctggag
1021 tctctgacag acaaatctaa ggagctgccg ttatactgtt ctggggggtt gcggtttttc
1081 tgggacaaca agtttgacca tgcaatggtg gctttcctgg actgtgtgca gcagttcaaa
1141 gaagaggttg agaaaggcga gacacgtttt tgtcttccct acaggatgga tgtggagaaa
1201 ggcaagattg aagacacagg aggcagtggc ggctcctatt ccatcaaaac ccagtttaac
1261 tctgaggagc agtggacaaa agctctcaag ttcatgctga cgaatcttaa gtggggtctt
1321 gcttgggtgt cctcacaatt ttataacaaa tga
//