LOCUS AF038963 3065 bp mRNA linear HUM 12-MAR-1999
DEFINITION Homo sapiens RNA helicase (RIG-I) mRNA, complete cds.
ACCESSION AF038963
VERSION AF038963.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3065)
AUTHORS Sun,Y.W.
TITLE RIG-I, a human homolog gene of RNA helicase, is induced by retinoic
acid during the differentiation of acute promyelocytic leukemia
cell
JOURNAL Thesis (1997) Shanghai Institute of Hematology, Rui-Jin Hospital,
Shanghai Second Medical University
REFERENCE 2 (bases 1 to 3065)
AUTHORS Yi-Wu,S.
TITLE Direct Submission
JOURNAL Submitted (17-DEC-1997) Rui-Jin Hospital, Shanghai Institute of
Hematology, Shanghai Second Medical University, 197, Rui-Jin Road
II, Shanghai, Shanghai 200025, P. R. China
FEATURES Location/Qualifiers
source 1..3065
/db_xref="H-InvDB:HIT000063457"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9p12"
/cell_line="NB4"
/cell_type="acute promyelocytic leukemia cell"
gene 1..3065
/gene="RIG-I"
CDS 158..2935
/gene="RIG-I"
/codon_start=1
/product="RNA helicase"
/protein_id="AAD19826.1"
/translation="MTTEQRRSLQAFQDYIRKTLDPTYILSYMAPWFREEEVQYIQAE
KNNKGPMEAATLFLKFLLELQEEGWFRGFLDALDHAGYSGLYEAIESWDFKKIEKLEE
YRLLLKRLQPEFKTRIIPTDIISDLSECLINQECEEILQICSTKGMMAGAEKLVECLL
RSDKENWPKTLKLALEKERNKFSELWIVEKGIKDVETEDLEDKMETSDIQIFYQEDPE
CQNLSENSCPPSEVSDTNLYSPFKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLL
ICEHHLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGISGATAENVPV
EQIVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNYLD
QKLGGSSGPLPQVIGLTASVGVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELE
QVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREFGTQK
YEQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDY
LKDFFSNVRAAGFEEIEQDLTQRFEEKLQELESVSRDPSNENPKLEDLCFILQEEYHL
NPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPAQKCIL
DAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFL
LTSNAGVIEKEQINMYKEKMMNDSILRLQTWDEAVFREKILHIQTHEKFIRDSQEKPK
PVPDKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSF
EKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFE
KIPFDPAEMSK"
BASE COUNT 1028 a 592 c 669 g 776 t
ORIGIN
1 tagttattaa agttcctatg cagctccgcc tccgtccggc ctcatttcct caaaaaatcc
61 ctgctttccc cgctcgccac gccctcctgc tacccggctt taaagctagt gaggcacagc
121 ctgcggggaa cgtagctagc tgcaagcaga ggccggcatg accaccgagc agcgacgcag
181 cctgcaagcc ttccaggatt atatccggaa gaccctggac cctacctaca tcctgagcta
241 catggccccc tggtttaggg aggaagaggt gcagtatatt caggctgaga aaaacaacaa
301 gggcccaatg gaggctgcca cactttttct caagttcctg ttggagctcc aggaggaagg
361 ctggttccgt ggctttttgg atgccctaga ccatgcaggt tattctggac tttatgaagc
421 cattgaaagt tgggatttca aaaaaattga aaagttggag gagtatagat tacttttaaa
481 acgtttacaa ccagaattta aaaccagaat tatcccaacc gatatcattt ctgatctgtc
541 tgaatgttta attaatcagg aatgtgaaga aattctacag atttgctcta ctaaggggat
601 gatggcaggt gcagagaaat tggtggaatg ccttctcaga tcagacaagg aaaactggcc
661 caaaactttg aaacttgctt tggagaaaga aaggaacaag ttcagtgaac tgtggattgt
721 agagaaaggt ataaaagatg ttgaaacaga agatcttgag gataagatgg aaacttctga
781 catacagatt ttctaccaag aagatccaga atgccagaat cttagtgaga attcatgtcc
841 accttcagaa gtgtctgata caaacttgta cagcccattt aaaccaagaa attaccaatt
901 agagcttgct ttgcctgcta tgaaaggaaa aaacacaata atatgtgctc ctacaggttg
961 tggaaaaacc tttgtttcac tgcttatatg tgaacatcat cttaaaaaat tcccacaagg
1021 acaaaagggg aaagttgtct tttttgcgaa tcagatccca gtgtatgaac agcagaaatc
1081 tgtattctca aaatactttg aaagacatgg gtatagagtt acaggcattt ctggagcaac
1141 agctgagaat gtcccagtgg aacagattgt tgagaacaat gacatcatca ttttaactcc
1201 acagattctt gtgaacaacc ttaaaaaggg aacgattcca tcactatcca tctttacttt
1261 gatgatattt gatgaatgcc acaacactag taaacaacac ccgtacaata tgatcatgtt
1321 taattatcta gatcagaaac ttggaggatc ttcaggccca ctgccccagg tcattgggct
1381 gactgcctcg gttggtgttg gggatgccaa aaacacagat gaagccttgg attatatctg
1441 caagctgtgt gcttctcttg atgcgtcagt gatagcaaca gtcaaacaca atctggagga
1501 actggagcaa gttgtttata agccccagaa gtttttcagg aaagtggaat cacggattag
1561 cgacaaattt aaatacatca tagctcagct gatgagggac acagagagtc tggcaaagag
1621 aatctgcaaa gacctcgaaa acttatctca aattcaaaat agggaatttg gaacacagaa
1681 atatgaacaa tggattgtta cagttcagaa agcatgcatg gtgttccaga tgccagacaa
1741 agatgaagag agcaggattt gtaaagccct gtttttatac acttcacatt tgcggaaata
1801 taatgatgcc ctcattatca gtgagcatgc acgaatgaaa gatgctctgg attacttgaa
1861 agacttcttc agcaatgtcc gagcagcagg attcgaagag attgagcaag atcttactca
1921 gagatttgaa gaaaagctgc aggaactaga aagtgtttcc agggatccca gcaatgagaa
1981 tcctaaactt gaagacctct gcttcatctt acaagaagag taccacttaa acccagagac
2041 aataacaatt ctctttgtga aaaccagagc acttgtggac gctttaaaaa attggattga
2101 aggaaatcct aaactcagtt ttctaaaacc tggcatattg actggacgtg gcaaaacaaa
2161 tcagaacaca ggaatgaccc tcccggcaca gaagtgtata ttggatgcat tcaaagccag
2221 tggagatcac aatattctga ttgccacctc agttgctgat gaaggcattg acattgcaca
2281 gtgcaatctt gtcatccttt atgagtatgt gggcaatgtc atcaaaatga tccaaaccag
2341 aggcagagga agagcaagag gtagcaagtg cttccttctg actagtaatg ctggtgtaat
2401 tgaaaaagaa caaataaaca tgtacaaaga aaaaatgatg aatgactcta ttttacgcct
2461 tcagacatgg gacgaagcag tatttaggga aaagattctg catatacaga ctcatgaaaa
2521 attcatcaga gatagtcaag aaaaaccaaa acctgtccct gataaggaaa ataaaaaact
2581 gctctgcaga aagtgcaaag ccttggcatg ttacacagct gacgtaagag tgatagagga
2641 atgccattac actgtgcttg gagatgcttt taaggaatgc tttgtgagta gaccacatcc
2701 caagccaaag cagttttcaa gttttgaaaa aagagcaaag atattctgtg cccgacagaa
2761 ctgcagccat gactggggaa tccatgtgaa gtacaagaca tttgagattc cagttataaa
2821 aattgaaagt tttgtggtgg aggatattgc aactggagtt cagacactgt actcgaagtg
2881 gaaggacttt cattttgaga agataccatt tgatccagca gaaatgtcca aatgatatca
2941 ggtcctcaat cttcagctac agggaatgag taactttgag tggagaagaa acaaacatag
3001 tgggtataat catggatcgc ttgtacccct gtgaaaatat attttttaaa aataaaaaaa
3061 aaaaa
//