LOCUS       JX974564                1167 bp    mRNA    linear   PLN 07-DEC-2012
DEFINITION  Catharanthus roseus iridoid synthase mRNA, complete cds.
ACCESSION   JX974564
VERSION     JX974564.1
KEYWORDS    .
SOURCE      Catharanthus roseus (Madagascar periwinkle)
  ORGANISM  Catharanthus roseus
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae;
            Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus.
REFERENCE   1  (bases 1 to 1167)
  AUTHORS   Geu-Flores,F., Sherden,N.H., Courdavault,V., Burlat,V., Glenn,W.S.,
            Wu,C., Nims,E., Cui,Y. and O'Connor,S.E.
  TITLE     An alternative route to cyclic terpenes by reductive cyclization in
            iridoid biosynthesis
  JOURNAL   Nature 492, 138-142 (2012)
   PUBMED   23172143
REFERENCE   2  (bases 1 to 1167)
  AUTHORS   Geu-Flores,F. and O'Connor,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-OCT-2012) Biological Chemistry, John Innes Centre,
            Norwich Research Park, Norwich NR4 7UH, UK
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..1167
                     /organism="Catharanthus roseus"
                     /mol_type="mRNA"
                     /cultivar="little bright eyes"
                     /db_xref="taxon:4058"
     CDS             1..1167
                     /function="converts 10-oxogeranial to nepetalactol in
                     iridoid biosynthesis"
                     /codon_start=1
                     /product="iridoid synthase"
                     /protein_id="AFW98981.1"
                     /translation="MSWWWKRSIGAGKNLPNQNKENGVCKSYKSVALVVGVTGIVGSS
                     LAEVLKLPDTPGGPWKVYGVARRPCPVWLAKKPVEYIQCDVSDNQETISKLSPLKDIT
                     HIFYVSWIGSEDCQTNATMFKNILNSVIPNASNLQHVCLQTGIKHYFGIFEEGSKVVP
                     HDSPFTEDLPRLNVPNFYHDLEDILYEETGKNNLTWSVHRPALVFGFSPCSMMNIVST
                     LCVYATICKHENKALVYPGSKNSWNCYADAVDADLVAEHEIWAAVDPKAKNQVLNCNN
                     GDVFKWKHIWKKLAEEFGIEMVGYVEGKEQVSLAELMKDKDQVWDEIVKKNNLVPTKL
                     KEIAAFWFADIAFCSENLISSMNKSKELGFLGFRNSMKSFVSCIDKMRDYRFIP"
BASE COUNT          372 a          175 c          262 g          358 t
ORIGIN      
        1 atgagttggt ggtggaagag gtccattggt gctggaaaga acttaccaaa ccagaacaaa
       61 gaaaatggag tttgtaaaag ctacaagagt gtggcactag tagtaggagt caccggcatt
      121 gttggcagta gtttagccga agttctaaag ctaccagaca cccctggagg tccctggaag
      181 gtatacggcg tggcaaggcg cccatgccct gtatggctag ccaaaaaacc agttgagtac
      241 atccaatgtg atgtctcaga taatcaagaa acaatttcta aattatctcc acttaaggac
      301 ataactcata tattctatgt ttcttggatt ggatcagaag attgccaaac aaatgctaca
      361 atgttcaaaa acatccttaa ttcagtgatt cctaatgctt caaatctcca acatgtgtgt
      421 ctccaaacag gaatcaaaca ttattttggt atttttgaag aaggttctaa agttgtacca
      481 catgattcgc cttttaccga ggatttacct aggctaaatg tcccaaattt ctaccatgat
      541 cttgaagata tactgtatga agaaactggc aagaacaatt taacatggtc tgtccataga
      601 ccagctctgg ttttcgggtt ttccccatgt agtatgatga acattgtcag tacattatgc
      661 gtttacgcca caatttgtaa acatgaaaat aaggccttgg tttatccagg tagtaaaaat
      721 tcatggaatt gttatgctga tgctgttgat gcagatttag tagccgagca cgaaatttgg
      781 gcagcagttg atcctaaggc taaaaatcaa gtattgaatt gtaacaatgg ggatgttttt
      841 aaatggaaac atatttggaa gaaattagca gaggaatttg ggattgaaat ggtgggatat
      901 gttgaaggta aagaacaagt tagtttggct gagttaatga aggataaaga tcaagtttgg
      961 gatgaaattg ttaagaagaa caatttagta cctactaaat tgaaagaaat tgctgccttt
     1021 tggtttgctg atattgcttt ttgttctgag aatttgatta gtagtatgaa caaaagtaag
     1081 gaattagggt tcttgggttt taggaattcg atgaaatcgt ttgtttcttg tattgataag
     1141 atgagggatt ataggtttat tccttag
//