LOCUS       Z23022                  3013 bp    mRNA    linear   HUM 14-NOV-2006
DEFINITION  H.sapiens of BCL1 mRNA encoding cyclin.
ACCESSION   Z23022
VERSION     Z23022.1
KEYWORDS    cyclin.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3013)
  AUTHORS   Rimokh R., Berger F., Bastard C., Klein B., French M.,
            Archimbaud E., Rouault J.P., Santa Lucia B., Duret L., Vuillaume M.
  TITLE     Rearrangement of CCND1 (BCL1/PRAD1) 3' untranslated region in
            mantle-cell lymphomas and t(11q13)-associated leukemias
  JOURNAL   Blood 83(12), 3689-3696(1994).
   PUBMED   8204893
REFERENCE   2  (bases 2276 to 3013)
  AUTHORS   Kaplan D.J., Jurka J., Solus J.F., Duncan C.H.
  TITLE     Medium reiteration frequency repetitive sequences in the human
            genome
  JOURNAL   Nucleic Acids Res. 19(17), 4731-4738(1991).
   PUBMED   1891362
REFERENCE   3  (bases 1 to 2275)
  AUTHORS   Motokura T., Bloom T., Jueppner H., Ruderman J., Kronenberg H.,
            Arnold A.
  TITLE     A novel cyclin encoded by a bcl1-linked candidate oncogene
  JOURNAL   Nature 350(6318), 512-515(1991).
   PUBMED   1826542
REFERENCE   4  (bases 1 to 3013)
  AUTHORS   Rimokh R.
  JOURNAL   Submitted (16-JUN-1993) to the INSDC. Ruth Rimokh, Laboratoire de
            Cytogenetique Moleculaire, Hopital, Edouard Herriot, Pavillon E,
            Place d'Arsonval, Lyon, 69437, FRANCE
FEATURES             Location/Qualifiers
     source          1..3013
                     /organism="Homo sapiens"
                     /chromosome="11q13.3"
                     /mol_type="mRNA"
                     /cell_type="tumoral lymphoid Bcell t(11:19)(q13:q13)
                     translocation"
                     /db_xref="taxon:9606"
     CDS             147..1034
                     /gene="BCL1"
                     /standard_name="PRAD1/BCL1 cyclin gene"
                     /product="cyclin"
                     /db_xref="GOA:P24385"
                     /db_xref="HGNC:HGNC:1582"
                     /db_xref="InterPro:IPR004367"
                     /db_xref="InterPro:IPR006671"
                     /db_xref="InterPro:IPR013763"
                     /db_xref="InterPro:IPR015451"
                     /db_xref="PDB:2W96"
                     /db_xref="PDB:2W99"
                     /db_xref="PDB:2W9F"
                     /db_xref="PDB:2W9Z"
                     /db_xref="UniProtKB/Swiss-Prot:P24385"
                     /protein_id="CAA80558.1"
                     /translation="MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSY
                     FKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLL
                     GATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDF
                     IEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLR
                     SPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEE
                     EEEEVDLACTPTDVRDVDI"
     misc_difference 870
                     /replace="a"
                     /note="conflict"
                     /citation=[3]
     misc_difference 1100
                     /replace="a"
                     /note="conflict"
                     /citation=[3]
     repeat_region   2276..3013
                     /rpt_family="MER11"
                     /citation=[2]
BASE COUNT          783 a          741 c          771 g          718 t
ORIGIN      
        1 gcgcagtagc agcgagcagc agagtccgca cgctccggcg aggggcagaa gagcgcgagg
       61 gagcgcgggg cagcagaagc gagagccgag cgcggaccca gccaggaccc acagccctcc
      121 ccagctgccc aggaagagcc ccagccatgg aacaccagct cctgtgctgc gaagtggaaa
      181 ccatccgccg cgcgtacccc gatgccaacc tcctcaacga ccgggtgctg cgggccatgc
      241 tgaaggcgga ggagacctgc gcgccctcgg tgtcctactt caaatgtgtg cagaaggagg
      301 tcctgccgtc catgcggaag atcgtcgcca cctggatgct ggaggtctgc gaggaacaga
      361 agtgcgagga ggaggtcttc ccgctggcca tgaactacct ggaccgcttc ctgtcgctgg
      421 agcccgtgaa aaagagccgc ctgcagctgc tgggggccac ttgcatgttc gtggcctcta
      481 agatgaagga gaccatcccc ctgacggccg agaagctgtg catctacacc gacaactcca
      541 tccggcccga ggagctgctg caaatggagc tgctcctggt gaacaagctc aagtggaacc
      601 tggccgcaat gaccccgcac gatttcattg aacacttcct ctccaaaatg ccagaggcgg
      661 aggagaacaa acagatcatc cgcaaacacg cgcagacctt cgttgccctc tgtgccacag
      721 atgtgaagtt catttccaat ccgccctcca tggtggcagc ggggagcgtg gtggccgcag
      781 tgcaaggcct gaacctgagg agccccaaca acttcctgtc ctactaccgc ctcacacgct
      841 tcctctccag agtgatcaag tgtgacccgg actgcctccg ggcctgccag gagcagatcg
      901 aagccctgct ggagtcaagc ctgcgccagg cccagcagaa catggacccc aaggccgccg
      961 aggaggagga agaggaggag gaggaggtgg acctggcttg cacacccacc gacgtgcggg
     1021 acgtggacat ctgagggcgc caggcaggcg ggcgccaccg ccacccgcag cgagggcgga
     1081 gccggcccca ggtgctcccc tgacagtccc tcctctccgg agcattttga taccagaagg
     1141 gaaagcttca ttctccttgt tgttggttgt tttttccttt gctctttccc ccttccatct
     1201 ctgacttaag caaaagaaaa agattaccca aaaactgtct ttaaaagaga gagagagaaa
     1261 aaaaaaatag tatttgcata accctgagcg gtgggggagg agggttgtgc tacagatgat
     1321 agaggatttt ataccccaat aatcaactcg tttttatatt aatgtacttg tttctctgtt
     1381 gtaagaatag gcattaacac aaaggaggcg tctcgggaga ggattaggtt ccatccttta
     1441 cgtgtttaaa aaaaagcata aaaacatttt aaaaacatag aaaaattcag caaaccattt
     1501 ttaaagtaga agagggtttt aggtagaaaa acatattctt gtgcttttcc tgataaagca
     1561 cagctgtagt ggggttctag gcatctctgt actttgcttg ctcatatgca tgtagtcact
     1621 ttataagtca ttgtatgtta ttatattccg taggtagatg tgtaacctct tcaccttatt
     1681 catggctgaa gtcacctctt ggttacagta gcgtagcgtg gccgtgtgca tgtcctttgc
     1741 gcctgtgacc accaccccaa caaaccatcc agtgacaaac catccagtgg aggtttgtcg
     1801 ggcaccagcc agcgtagcag ggtcgggaaa ggccacctgt cccactccta cgatacgcta
     1861 ctataaagag aagacgaaat agtgacataa tatattctat ttttatactc ttcctatttt
     1921 tgtagtgacc tgtttatgag atgctggttt tctacccaac ggccctgcag ccagctcacg
     1981 tccaggttca acccacagct acttggtttg tgttcttctt catattctaa aaccattcca
     2041 tttccaagca ctttcagtcc aataggtgta ggaaatagcg ctgtttttgt tgtgtgtgca
     2101 gggagggcag ttttctaatg gaatggtttg ggaatatcca tgtacttgtt tgcaagcagg
     2161 actttgaggc aagtgtgggc cactgtggtg gcagtggagg tggggtgttt gggaggctgc
     2221 gtgccagtca agaagaaaaa ggtttgcatt ctcacattgc caggatgata agttcaactg
     2281 agccttaaac cagcaagttt tttattaagg gtttcaagag gggagggggt gtgagaacat
     2341 ggagtagagc tcatgcttca aagggcaaaa aacagaacaa agatcacttg cttctgaggg
     2401 aacaggagaa aaggcaacac agaactactg ataagggtcc atgttcagcg gtgcacgtat
     2461 tatcttgata aacatcttga acaaaaaata gggaaacgtc tgaccacaaa ttcaccaggg
     2521 tggagttttt ccccaccgta gtaagcctga gggtactgca ggagatcagg gcgtatctca
     2581 gtccttatct caaccacgta agacagacat tcccagagca gctgtttata gacctctccc
     2641 caggaatgca ttcctttccc agggtattaa tattaatatt gcttgctagg aaaagaattt
     2701 agcgatatcc tccctacttg catgtccttt tataggctct ctgcaagaag aaaaatatgg
     2761 ctttttttgc ctgaccctgc aggcagtcag accttatggt tgtcttccct tgttccctaa
     2821 aatcgctgtt attctgtttt ttctcaaggt gcactgattt catattgttc aaacacacgt
     2881 tttacaatca atttgtacag ttaacacaat tatcacggtg gtcctgaggt gacatacatc
     2941 ctcagcttac gaagataaca ggattaagag atgagagtaa gacaggcgta agaaattata
     3001 aaagtattaa ttt
//