LOCUS Y08890 4826 bp mRNA linear HUM 07-OCT-2008
DEFINITION Homo spaiens mRNA for Ran_GTP binding protein 5 (RanBP5(Importin5)
gene).
ACCESSION Y08890
VERSION Y08890.1
KEYWORDS RanBP5(Importin5) gene; Ran_GTP binding protein 5.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Deane R., Schaffer W., Zimmermann H.P., Mueller L., Goerlich D.,
Prehn S., Ponstingl H., Bischoff F.R.
TITLE Ran-binding protein 5 (RanBP5) is related to the nuclear transport
factor importin-beta but interacts differently with RanBP1
JOURNAL Mol. Cell. Biol. 17(9), 5087-5096(1997).
PUBMED 9271386
REFERENCE 2 (bases 1 to 4822)
AUTHORS Deane R.
JOURNAL Submitted (16-OCT-1996) to the INSDC. R. Deane, German Cancer
Research Center, Molekulare Biologie der Mitosis, Abt. 0230, Im
Neuenheimer Feld 280, 69120 Heidelberg, FRG
REFERENCE 3
AUTHORS Jakel S., Gorlich D.
TITLE Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear
import of ribosomal proteins in mammalian cells
JOURNAL EMBO J. 17(15), 4491-4502(1998).
PUBMED 9687515
FEATURES Location/Qualifiers
source 1..4826
/db_xref="H-InvDB:HIT000325484"
/organism="Homo sapiens"
/lab_host="AM1"
/lab_host="DH5a"
/mol_type="mRNA"
/clone_lib="HeLa 5' strech (lDR2, Clontech)"
/db_xref="taxon:9606"
CDS 237..3530
/gene="RanBP5(Importin5)"
/product="Ran_GTP binding protein 5"
/function="nuclear import receptor for ribosomal proteins
such as RL23a"
/note="RanBP5 is a predominantly cytoplasmic protein that
can bind to nuclear pore complexes"
/db_xref="GOA:O00410"
/db_xref="H-InvDB:HIT000325484.14"
/db_xref="HGNC:HGNC:6402"
/db_xref="InterPro:IPR000357"
/db_xref="InterPro:IPR001494"
/db_xref="InterPro:IPR016024"
/db_xref="InterPro:IPR034085"
/db_xref="InterPro:IPR040122"
/db_xref="InterPro:IPR041389"
/db_xref="InterPro:IPR041653"
/db_xref="UniProtKB/Swiss-Prot:O00410"
/protein_id="CAA70103.1"
/translation="MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKITF
LLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQ
SSMRKKVCDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPG
IFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLL
PGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQR
QLALEVIVTLSETAAAMLRKHTNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDS
NAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQ
MEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTM
EDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLV
LEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGL
AVGKEKFMQDASDVMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLP
VVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTAC
QMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPE
YLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILK
AKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYKEK
VLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYV
CDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENC
ISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFNYLCDLIESNHPIVLGP
NNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTECIAQLSPEQQA
AIQELLNSA"
regulatory 4772..4777
/gene="RanBP5(Importin5)"
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1471 a 952 c 1055 g 1348 t
ORIGIN
1 tctcactata gggctcgagc ggccgcccgg gcaggtctga ccacagtggt tccggggaga
61 agccttccag gacccatgtg taggcacaac tgttttccct gatcaggata cttccggcac
121 tcaacagagg aaagaaattc ctaagggaac actgctcaga aagtactgca gcatgtcttc
181 aaatgcctga ggatcaagtt ggaaaactag aagcaacaga aaacacaata agcgcaatgg
241 cggcggccgc ggcggagcag caacagttct acctgctgct gggaaacctg ctcagccccg
301 acaatgtggt ccggaaacag gcagaggaaa cctatgagaa tatcccaggc cagtcaaaga
361 tcacattcct cttacaagcc atcagaaata caacagctgc tgaagaggct agacaaatgg
421 ccgccgttct cctaagacgt ctcttgtcct ctgcatttga tgaagtctat ccagcacttc
481 cctctgatgt tcagactgcc atcaagagtg agctactcat gattattcag atggaaacac
541 aatctagcat gaggaaaaaa gtttgtgata ttgcggcaga actggccagg aatttaatag
601 atgaggatgg caataaccag tggcccgaag gtttgaagtt cctttttgat tcagtcagct
661 ctcaaaatgt gggactgcgg gaagctgccc ttcacatttt ctggaacttt cctggaattt
721 ttgggaacca gcaacaacac tatttagatg tcatcaaacg aatgttagtt cagtgtatgc
781 aagatcagga acacccgtcg atcaggacgt tatctgctag agctacagct gcatttatac
841 ttgcaaatga gcataatgtt gctctgttca aacattttgc agacttgcta ccgggattcc
901 tacaggcggt aaatgactcg tgctaccaga atgatgattc tgtcctaaaa tccctcgttg
961 agattgcaga tactgttcca aagtatttgc gtcctcactt ggaagcaact ctacagctaa
1021 gtctaaagtt gtgtggagac actagcctca acaatatgca acgccagctt gcccttgaag
1081 tgatcgtcac cctctctgag actgcagctg ctatgttaag aaaacatacc aatattgttg
1141 cacagactat tcctcagatg ttagcaatga tggttgattt ggaagaagat gaggactggg
1201 caaatgcaga tgaactagaa gatgatgatt ttgacagcaa tgcagttgca ggcgagagtg
1261 ctctagatcg aatggcttgc ggacttggtg gaaagctcgt tctgccgatg atcaaggaac
1321 acattatgca aatgcttcaa aatcctgact ggaaataccg gcatgcagga ttgatggcct
1381 tatctgccat tggtgaaggg tgccaccagc aaatggaagg aattctaaat gagatcgtaa
1441 attttgtttt actttttctc caggatcctc atccaagagt aaggtatgca gcctgtaatg
1501 ccgtgggaca gatggctaca gattttgcac ctggtttcca aaagaaattt catgagaagg
1561 tgattgcagc tctgctgcag accatggaag accaaggcaa tcaacgtgtg caggcccatg
1621 cagctgctgc cctcattaac tttactgaag actgtcccaa gtcactactt attccatact
1681 tggataattt ggtgaaacat ctgcattcca ttatggtact gaagcttcaa gagctgattc
1741 agaaaggcac caagttagtt ttggaacaag ttgtgacatc cattgcatca gttgccgata
1801 ctgcagaaga aaaatttgtc ccctactatg atttatttat gccatcactg aagcacatcg
1861 ttgagaatgc ggttcaaaaa gaactgagac ttctgagagg aaaaactatt gaatgcatta
1921 gcctcattgg tctggctgtt gggaaggaaa aattcatgca ggatgcatca gatgtgatgc
1981 agcttttgtt aaagacccag acagacttca atgatatgga agatgatgat cctcagatct
2041 cttacatgat ctcagcatgg gccagaatgt gcaaaatcct tggaaaagaa tttcagcaat
2101 accttccagt ggttatgggg cctttaatga agacggcttc aattaagccc gaagtagccc
2161 ttttagatac ccaagacatg gagaatatga gtgatgatga tggttgggaa tttgtgaacc
2221 ttggagatca gcaaagcttt ggtattaaaa ctgcaggact agaagaaaaa tcaactgctt
2281 gccagatgtt ggtttgctat gctaaggagt taaaggaagg ctttgtggag tacaccgaac
2341 aggttgtcaa actgatggtc cctttactga aattttattt ccacgatggt gttcgagtgg
2401 cagcagcgga atccatgcct cttctcctgg agtgtgcaag agtccgtggt cctgagtatc
2461 tcacacagat gtggcatttt atgtgtgatg ctctaattaa ggccattggt acagaaccag
2521 attcagacgt cctctcagaa ataatgcatt cttttgcaaa gtgcattgaa gtaatgggag
2581 atggatgcct taataatgaa cactttgaag aactgggagg tatattgaaa gcaaagcttg
2641 aagaacattt taaaaatcaa gaattacgac aagttaaaag acaagatgaa gactatgatg
2701 aacaggtcga agagtcacta caagatgagg atgataatga tgtttatatt ctgaccaaag
2761 tgtcagatat tttacactca atattcagta gctacaaaga aaaggtgtta ccatggtttg
2821 aacagctgct tccattaatt gtcaacctca tttgtccaca tagaccatgg ccagacagac
2881 aatggggatt atgcatcttt gatgatgtca tagaacactg tagtccagcc tcatttaaat
2941 acgcagaata tttcttaaga ccaatgctcc aatatgtatg tgacaacagc ccagaagtca
3001 ggcaagcagc tgcatatggc ctgggagtca tggcacagta cggtggagat aattatcgcc
3061 ctttttgtac agaagcactt cccctgctgg taagagttat tcagtctgcg gattctaaga
3121 ccaaagaaaa tgtcaatgct acagagaact gcatctcagc agtagggaaa atcatgaagt
3181 tcaagcctga ctgtgtaaac gttgaagagg tccttccaca ctggttgtct tggcttccac
3241 tacatgaaga taaagaagaa gctgttcaga ctttcaatta tctgtgtgac ctgattgaaa
3301 gtaatcatcc aattgttctt ggcccaaaca ataccaatct gcccaaaata tttagtataa
3361 ttgcggaagg agaaatgcac gaggcaatta aacatgaaga tccttgtgcc aaacgtctgg
3421 ccaatgtcgt tcgccaagta cagacttctg gaggactgtg gactgagtgc atagcacagc
3481 tcagtcctga gcagcaggcc gccattcagg agctcctgaa ctctgcgtga agggccttaa
3541 tgtcacccac cagaaaacta actccaaata aacgcttacc ctttccttta ggtttctttg
3601 ttttgttttt gagcaaaaga gatcggtagt gttgtgtgta ggccattctt ctggagagcc
3661 acaagcagga agagcagcgc tgtgttgcag aatggagttt ccatggattt ctaccagacc
3721 actgaaggag ttcctggaag ccctgcgtac gtagcactga agactatttt tctattggta
3781 taacccgccc acctgaaggg gaaagggaaa tcaaattaat ttttctcgtt agacataagg
3841 aaatttaagg aaaaacagct ttaagaacag ttactcagcg tagatgtgtg ttcacacaaa
3901 ttgccttgca ttcagtgttc attgtgaatt gggagtgtga gtctttctgt agggtacaaa
3961 gaagcctcct acccagcaaa ccagtagacc caaaagttga aaaaaactgg atgacagaca
4021 acaagcatga agatggcata tttgatgtca ctttggttct ttttcccaga aggcttatac
4081 agtgactcag tcgggaagct ttccagcttc agcccttgaa tgtgaagtgt cattggcatg
4141 tctggcagta gtctctcatt cactcccaat aaacaacatt gaatacaaaa gaggcttgtg
4201 taaaaactca gtactgtctg gcttggattc atttcatgtt ttttaatata agaatgatct
4261 aatatttttt taaagtaata gctatcagta atagctgagt gttttttccc ctaatatttt
4321 ccttgtgcaa ttcagactta agcatcgagt ttttaccatc ttccacttta agctaagtta
4381 tgatacctat tccattcaca attggtgttc tttttaaggt ttgcaaattt cagccaattt
4441 tgtagctaag attgttctga tcagctcaaa aagatttggc ttagtgtttt cattgcaaat
4501 tataattgct gtagagccac acacaacttt tgaactttta attataagtg ttatggctaa
4561 agttatttac tgaaaatttc agtaaaatgt gtgaatgttt ctttatgtat taacctcata
4621 gcagtaaatg acttgctgtt gtttaatttt tctaaggcat cttaatagac ttctcttgga
4681 aaaacctttc caaggtgtta acatttttat agtttgtact aaatttaacc gtgatataaa
4741 aatgaatttt atgcatagat cagaatttta aattaaaggt tttttcttta aaaaaaaaaa
4801 aaaaaaaaaa aaaaaaaaaa aaaaaa
//