LOCUS Y00345 2848 bp mRNA linear HUM 12-SEP-1993
DEFINITION Human mRNA for polyA binding protein.
ACCESSION Y00345
VERSION Y00345.1
KEYWORDS polyA binding protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2848)
AUTHORS Grange T., Pictet R.
JOURNAL Submitted (11-JUN-1987) to the INSDC. Thierry Grange and R. Pictet,
CNRS, Institut J.Monod, Universite Paris 7 Tour 43, 2 place
Jussieu, Paris 75005.
REFERENCE 2
AUTHORS Grange T., Martin de Sa C., Oddos J., Pictet R.
TITLE Human mRNA polyadenylate binding protein: evolutionary conservation
of a nucleic acid binding motif
JOURNAL Nucleic Acids Res. 15(12), 4771-4787(1987).
PUBMED 2885805
COMMENT Data kindly reviewed (06-JUN-1987) by Pictet R.
FEATURES Location/Qualifiers
source 1..2848
/db_xref="H-InvDB:HIT000325282"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_line="Melanoma cell (Bowes)"
/db_xref="taxon:9606"
misc_feature 70..131
/note="A rich sequence"
CDS 503..2404
/note="polyA binding protein (AA 1-633)"
/db_xref="GOA:P11940"
/db_xref="H-InvDB:HIT000325282.13"
/db_xref="HGNC:HGNC:8554"
/db_xref="InterPro:IPR000504"
/db_xref="InterPro:IPR002004"
/db_xref="InterPro:IPR003954"
/db_xref="InterPro:IPR006515"
/db_xref="InterPro:IPR012677"
/db_xref="InterPro:IPR035979"
/db_xref="InterPro:IPR036053"
/db_xref="PDB:1CVJ"
/db_xref="PDB:1G9L"
/db_xref="PDB:1JGN"
/db_xref="PDB:1JH4"
/db_xref="PDB:2K8G"
/db_xref="PDB:2RQG"
/db_xref="PDB:2RQH"
/db_xref="PDB:2X04"
/db_xref="PDB:3KTP"
/db_xref="PDB:3KTR"
/db_xref="PDB:3KUI"
/db_xref="PDB:3KUJ"
/db_xref="PDB:3KUR"
/db_xref="PDB:3KUS"
/db_xref="PDB:3KUT"
/db_xref="PDB:3PKN"
/db_xref="PDB:3PTH"
/db_xref="PDB:4F02"
/db_xref="PDB:4F25"
/db_xref="PDB:4F26"
/db_xref="PDB:5DX1"
/db_xref="PDB:5DX8"
/db_xref="PDB:5DXA"
/db_xref="PDB:5LGP"
/db_xref="PDB:5LGQ"
/db_xref="PDB:5LGR"
/db_xref="PDB:5LGS"
/db_xref="UniProtKB/Swiss-Prot:P11940"
/protein_id="CAA68428.1"
/translation="MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCR
DMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIF
IKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG
MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGPALSVK
VMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRK
FEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGF
VCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNP
VINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQVAQLRPSPRWTAQGARPHPFQNMPGA
IRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQY
KYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPL
IQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAV
NSATGVPTV"
misc_feature 542..1627
/note="4x repeated motif"
misc_feature 1670..2173
/note="proline rich domain"
misc_feature 2508..2513
/note="alternate polyA signal"
misc_feature 2512..2517
/note="alternate polyA signal"
misc_feature 2827..2832
/note="put. polyA signal"
polyA_site 2848..2848
/note="polyA site"
BASE COUNT 841 a 694 c 621 g 692 t
ORIGIN
1 ccttctcccc ggcggttagt gctgagagtg cggagtgtgt gctccgggct cggaacacac
61 atttattatt aaaaaatcca aaaaaaatct aaaaaaatct tttaaaaaac cccaaaaaaa
121 tttacaaaaa atccgcgtct cccccgccgg agacttttat tttttttctt cctcttttat
181 aaaataaccc ggtgaagcag ccgagaccga cccgcccgcc cgcggccccg cagcagctcc
241 aagaaggaac caagagaccg aggccttccc gctgcccgga cccgacaccg ccaccctcgc
301 tccccgccgg cagccggcag ccagcggcag tggatcgacc ccgttctgcg gccgttgagt
361 agttttcaat tccggttgat ttttgtccct ctgcgcttgc tccccgctcc cctccccccg
421 gctccggccc ccagccccgg cactcgctct cctcctctca cggaaaggtc gcggcctgtg
481 ccctgcgggc agccgtgccg agatgaaccc cagtgccccc agctacccca tggcctcgct
541 ctacgtgggg gacctccacc ccgacgtgac cgaggcgatg ctctacgaga agttcagccc
601 ggccgggccc atcctctcca tccgggtctg cagggacatg atcacccgcc gctccttggg
661 ctacgcgtat gtgaacttcc agcagccggc ggacgcggag cgtgctttgg acaccatgaa
721 ttttgatgtt ataaagggca agccagtacg catcatgtgg tctcagcgtg atccatcact
781 tcgcaaaagt ggagtaggca acatattcat taaaaatctg gacaaatcca ttgataataa
841 agcactgtat gatacatttt ctgcttttgg taacatcctt tcatgtaagg tggtttgtga
901 tgaaaatggt tccaagggct acggatttgt acactttgag acgcaggaag cagctgaaag
961 agctattgaa aaaatgaatg gaatgctcct aaatgatcgc aaagtatttg ttggacgatt
1021 taagtctcgt aaagaacgag aagctgaact tggagctagg gcaaaagaat tcaccaatgt
1081 ttacatcaag aattttggag aagacatgga tgatgagcgc cttaaggatc tctttgggcc
1141 tgccttaagt gtgaaagtaa tgactgatga aagtggaaaa tccaaaggat ttggatttgt
1201 aagctttgaa aggcatgaag atgcacagaa agctgtggat gagatgaacg gaaaggagct
1261 caatggaaaa caaatttatg ttggtcgagc tcagaaaaag gtggaacggc agacggaact
1321 taagcgcaaa tttgaacaga tgaaacaaga taggatcacc agataccagg gtgttaatct
1381 ttatgtgaaa aatcttgatg atggtattga tgatgaacgt ctccggaaag agttttctcc
1441 atttggtaca atcactagtg caaaggttat gatggagggt ggtcgcagca aagggtttgg
1501 ttttgtatgt ttctcctccc cagaagaagc cactaaagca gttacagaaa tgaacggtag
1561 aattgtggcc acaaagccat tgtatgtagc tttagctcag cgcaaagaag agcgccaggc
1621 tcacctcact aaccagtata tgcagagaat ggcaagtgta cgagctgttc ccaaccctgt
1681 aatcaacccc taccagccag cacctccttc aggttacttc atggcagcta tcccacagac
1741 tcagaaccgt gctgcatact atcctcctag ccaagttgct caactaagac caagtcctcg
1801 ctggactgct cagggtgcca gacctcatcc attccaaaat atgcccggtg ctatccgccc
1861 agctgctcct agaccaccat ttagtactat gagaccagct tcttcacagg ttccacgagt
1921 catgtcaaca cagcgtgttg ctaacacatc aacacagaca atgggtccac gtcctgcagc
1981 tgcagccgct gcagctactc ctgctgtccg caccgttcca cagtataaat atgctgcagg
2041 agttcgcaat cctcagcaac atcttaatgc acagccacaa gttacaatgc aacagcctgc
2101 tgttcatgta caaggtcagg aacctttgac tgcttccatg ttggcatctg cccctcctca
2161 agagcaaaag caaatgttgg gtgaacggct gtttcctctt attcaagcca tgcaccctac
2221 tcttgctggt aaaatcactg gcatgttgtt ggagattgat aattcagaac ttcttcatat
2281 gctcgagtct ccagagtcac tccgttctaa ggttgatgaa gctgtagctg tactacaagc
2341 ccaccaagct aaagaggctg cccagaaagc agttaacagt gccaccggtg ttccaactgt
2401 ttaaaattga tcagggacca tgaaaagaaa cttgtgcttc accgaagaaa aatatctaaa
2461 catcgaaaaa cttaaatatt atggaaaaaa aacattgcaa aatataaaat aaataaaaaa
2521 aggaaaggaa actttgaacc ttatgtaccg agcaaatgcc aggtctagca aacataatgc
2581 tagtcctaga ttacttattg atttaaaaac aaaaaaacac aaaaaatagt aaaatataaa
2641 aacaaattaa tgttttatag accctgggaa aaagaatttt cagcaaagta caaaaattta
2701 aagcattcct ttctttaatt ttgtaattct ttactgtgga atagctcaga atgtcagttc
2761 tgttttaagt aacagaattg ataactgagc aaggaaacgt aatttggatt ataaaattct
2821 tgctttaata aaaattcctt aaacagtg
//