LOCUS       X87838                  3362 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  H.sapiens mRNA for beta-catenin.
ACCESSION   X87838
VERSION     X87838.1
KEYWORDS    beta-catenin.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1
  AUTHORS   Nollet,F., Berx,G., Molemans,F. and  van,Roy,F.
  TITLE     Genomic organization of the human beta-catenin gene (CTNNB1)
  JOURNAL   Genomics 32(3), 413-424(1996).
   PUBMED   8838805
REFERENCE   2
  AUTHORS   Nollet,F.H.
  JOURNAL   Submitted (07-JUN-1995) to the INSDC. F.H. Nollet, Laboratory of
            Molecular Biology, Section Molecular Cell Biology, K.L.
            Ledeganckstraat 35, B-9000 Ghent, Belgium
  REMARK    Revised by [4]
REFERENCE   3  (bases 17 to 2596)
  AUTHORS   Huelsken,J., Birchmeier,W. and  Behrens,J.
  TITLE     E-cadherin and APC compete for the interaction with beta-catenin
            and the cytoskeleton.
  JOURNAL   J. Cell Biol. 127(6 Pt 2), 2061-2069(1994).
   PUBMED   7806582
REFERENCE   4  (bases 1 to 3362)
  AUTHORS   Nollet,F.H.
  JOURNAL   Submitted (12-JAN-1996) to the INSDC. F.H. Nollet, Laboratory of
            Molecular Biology, Section Molecular Cell Biology, K.L.
            Ledeganckstraat 35, B-9000 Ghent, Belgium
FEATURES             Location/Qualifiers
     source          1..3362
                     /db_xref="H-InvDB:HIT000324313"
                     /organism="Homo sapiens"
                     /chromosome="3"
                     /map="p21"
                     /mol_type="mRNA"
                     /cell_line="5637"
                     /db_xref="taxon:9606"
     CDS             215..2560
                     /product="beta-catenin"
                     /db_xref="GOA:P35222"
                     /db_xref="H-InvDB:HIT000324313.15"
                     /db_xref="HGNC:HGNC:2514"
                     /db_xref="InterPro:IPR000225"
                     /db_xref="InterPro:IPR011989"
                     /db_xref="InterPro:IPR013284"
                     /db_xref="InterPro:IPR016024"
                     /db_xref="PDB:1G3J"
                     /db_xref="PDB:1JDH"
                     /db_xref="PDB:1JPW"
                     /db_xref="PDB:1LUJ"
                     /db_xref="PDB:1P22"
                     /db_xref="PDB:1QZ7"
                     /db_xref="PDB:1T08"
                     /db_xref="PDB:1TH1"
                     /db_xref="PDB:2G57"
                     /db_xref="PDB:2GL7"
                     /db_xref="PDB:2Z6H"
                     /db_xref="PDB:3DIW"
                     /db_xref="PDB:3FQN"
                     /db_xref="PDB:3FQR"
                     /db_xref="PDB:3SL9"
                     /db_xref="PDB:3SLA"
                     /db_xref="PDB:3TX7"
                     /db_xref="PDB:4DJS"
                     /db_xref="UniProtKB/Swiss-Prot:P35222"
                     /protein_id="CAA61107.1"
                     /translation="MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAP
                     SLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPET
                     LDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLL
                     NDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTL
                     HNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLA
                     GGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYE
                     KLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA
                     TKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRT
                     VLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIK
                     ATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRM
                     EEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQD
                     KEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSL
                     FRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMG
                     GHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL"
     misc_feature    2573..2731
                     /note="alternatively spliced fragment"
BASE COUNT          880 a          707 c          822 g          953 t
ORIGIN
        1 aagcctctcg gtctgtggca gcagcgttgg cccggccccg ggagcggaga gcgaggggag
       61 gcggagacgg aggaaggtct gaggagcagc ttcagtcccc gccgagccgc caccgcaggt
      121 cgaggacggt cggactcccg cggcgggagg agcctgttcc cctgagggta tttgaagtat
      181 accatacaac tgttttgaaa atccagcgtg gacaatggct actcaagctg atttgatgga
      241 gttggacatg gccatggaac cagacagaaa agcggctgtt agtcactggc agcaacagtc
      301 ttacctggac tctggaatcc attctggtgc cactaccaca gctccttctc tgagtggtaa
      361 aggcaatcct gaggaagagg atgtggatac ctcccaagtc ctgtatgagt gggaacaggg
      421 attttctcag tccttcactc aagaacaagt agctgatatt gatggacagt atgcaatgac
      481 tcgagctcag agggtacgag ctgctatgtt ccctgagaca ttagatgagg gcatgcagat
      541 cccatctaca cagtttgatg ctgctcatcc cactaatgtc cagcgtttgg ctgaaccatc
      601 acagatgctg aaacatgcag ttgtaaactt gattaactat caagatgatg cagaacttgc
      661 cacacgtgca atccctgaac tgacaaaact gctaaatgac gaggaccagg tggtggttaa
      721 taaggctgca gttatggtcc atcagctttc taaaaaggaa gcttccagac acgctatcat
      781 gcgttctcct cagatggtgt ctgctattgt acgtaccatg cagaatacaa atgatgtaga
      841 aacagctcgt tgtaccgctg ggaccttgca taacctttcc catcatcgtg agggcttact
      901 ggccatcttt aagtctggag gcattcctgc cctggtgaaa atgcttggtt caccagtgga
      961 ttctgtgttg ttttatgcca ttacaactct ccacaacctt ttattacatc aagaaggagc
     1021 taaaatggca gtgcgtttag ctggtgggct gcagaaaatg gttgccttgc tcaacaaaac
     1081 aaatgttaaa ttcttggcta ttacgacaga ctgccttcaa attttagctt atggcaacca
     1141 agaaagcaag ctcatcatac tggctagtgg tggaccccaa gctttagtaa atataatgag
     1201 gacctatact tacgaaaaac tactgtggac cacaagcaga gtgctgaagg tgctatctgt
     1261 ctgctctagt aataagccgg ctattgtaga agctggtgga atgcaagctt taggacttca
     1321 cctgacagat ccaagtcaac gtcttgttca gaactgtctt tggactctca ggaatctttc
     1381 agatgctgca actaaacagg aagggatgga aggtctcctt gggactcttg ttcagcttct
     1441 gggttcagat gatataaatg tggtcacctg tgcagctgga attctttcta acctcacttg
     1501 caataattat aagaacaaga tgatggtctg ccaagtgggt ggtatagagg ctcttgtgcg
     1561 tactgtcctt cgggctggtg acagggaaga catcactgag cctgccatct gtgctcttcg
     1621 tcatctgacc agccgacacc aagaagcaga gatggcccag aatgcagttc gccttcacta
     1681 tggactacca gttgtggtta agctcttaca cccaccatcc cactggcctc tgataaaggc
     1741 tactgttgga ttgattcgaa atcttgccct ttgtcccgca aatcatgcac ctttgcgtga
     1801 gcagggtgcc attccacgac tagttcagtt gcttgttcgt gcacatcagg atacccagcg
     1861 ccgtacgtcc atgggtggga cacagcagca atttgtggag ggggtccgca tggaagaaat
     1921 agttgaaggt tgtaccggag cccttcacat cctagctcgg gatgttcaca accgaattgt
     1981 tatcagagga ctaaatacca ttccattgtt tgtgcagctg ctttattctc ccattgaaaa
     2041 catccaaaga gtagctgcag gggtcctctg tgaacttgct caggacaagg aagctgcaga
     2101 agctattgaa gctgagggag ccacagctcc tctgacagag ttacttcact ctaggaatga
     2161 aggtgtggcg acatatgcag ctgctgtttt gttccgaatg tctgaggaca agccacaaga
     2221 ttacaagaaa cggctttcag ttgagctgac cagctctctc ttcagaacag agccaatggc
     2281 ttggaatgag actgctgatc ttggacttga tattggtgcc cagggagaac cccttggata
     2341 tcgccaggat gatcctagct atcgttcttt tcactctggt ggatatggcc aggatgcctt
     2401 gggtatggac cccatgatgg aacatgagat gggtggccac caccctggtg ctgactatcc
     2461 agttgatggg ctgccagatc tggggcatgc ccaggacctc atggatgggc tgcctccagg
     2521 tgacagcaat cagctggcct ggtttgatac tgacctgtaa atcatccttt agctgtattg
     2581 tctgaacttg cattgtgatt ggcctgtaga gttgctgaga gggctcgagg ggtgggctgg
     2641 tatctcagaa agtgcctgac acactaacca agctgagttt cctatgggaa caattgaagt
     2701 aaactttttg ttctggtcct ttttggtcga ggagtaacaa tacaaatgga ttttgggagt
     2761 gactcaagaa gtgaagaatg cacaagaatg gatcacaaga tggaatttag caaaccctag
     2821 ccttgcttgt taaaattttt tttttttttt ttttaagaat atctgtaatg gtactgactt
     2881 tgcttgcttt gaagtagctc tttttttttt tttttttttt tttttttgca gtaactgttt
     2941 tttaagtctc tcgtagtgtt aagttatagt gaatactgct acagcaattt ctaattttta
     3001 agaattgagt aatggtgtag aacactaatt aattcataat cactctaatt aattgtaatc
     3061 tgaataaagt gtaacaattg tgtagccttt ttgtataaaa tagacaaata gaaaatggtc
     3121 caattagttt cctttttaat atgcttaaaa taagcaggtg gatctatttc atgtttttga
     3181 tcaaaaacta tttgggatat gtatgggtag ggtaaatcag taagaggtgt tatttggaac
     3241 cttgttttgg acagtttacc agttgccttt tatcccaaag ttgttgtaac ctgctgtgat
     3301 acgatgcttc aagagaaaat gcggttataa aaaatggttc agaattaaac ttttaattca
     3361 tt
//