LOCUS X87838 3362 bp mRNA linear HUM 07-OCT-2008
DEFINITION H.sapiens mRNA for beta-catenin.
ACCESSION X87838
VERSION X87838.1
KEYWORDS beta-catenin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Nollet F., Berx G., Molemans F., van Roy F.
TITLE Genomic organization of the human beta-catenin gene (CTNNB1)
JOURNAL Genomics 32(3), 413-424(1996).
PUBMED 8838805
REFERENCE 2
AUTHORS Nollet F.H.
JOURNAL Submitted (07-JUN-1995) to the INSDC. F.H. Nollet, Laboratory of
Molecular Biology, Section Molecular Cell Biology, K.L.
Ledeganckstraat 35, B-9000 Ghent, Belgium
REMARK Revised by [4]
REFERENCE 3 (bases 17 to 2596)
AUTHORS Huelsken J., Birchmeier W., Behrens J.
TITLE E-cadherin and APC compete for the interaction with beta-catenin
and the cytoskeleton.
JOURNAL J. Cell Biol. 127(6 Pt 2), 2061-2069(1994).
PUBMED 7806582
REFERENCE 4 (bases 1 to 3362)
AUTHORS Nollet F.H.
JOURNAL Submitted (12-JAN-1996) to the INSDC. F.H. Nollet, Laboratory of
Molecular Biology, Section Molecular Cell Biology, K.L.
Ledeganckstraat 35, B-9000 Ghent, Belgium
FEATURES Location/Qualifiers
source 1..3362
/db_xref="H-InvDB:HIT000324313"
/organism="Homo sapiens"
/chromosome="3"
/map="p21"
/mol_type="mRNA"
/cell_line="5637"
/db_xref="taxon:9606"
CDS 215..2560
/product="beta-catenin"
/db_xref="GOA:P35222"
/db_xref="H-InvDB:HIT000324313.15"
/db_xref="HGNC:HGNC:2514"
/db_xref="InterPro:IPR000225"
/db_xref="InterPro:IPR011989"
/db_xref="InterPro:IPR013284"
/db_xref="InterPro:IPR016024"
/db_xref="PDB:1G3J"
/db_xref="PDB:1JDH"
/db_xref="PDB:1JPW"
/db_xref="PDB:1LUJ"
/db_xref="PDB:1P22"
/db_xref="PDB:1QZ7"
/db_xref="PDB:1T08"
/db_xref="PDB:1TH1"
/db_xref="PDB:2G57"
/db_xref="PDB:2GL7"
/db_xref="PDB:2Z6H"
/db_xref="PDB:3DIW"
/db_xref="PDB:3FQN"
/db_xref="PDB:3FQR"
/db_xref="PDB:3SL9"
/db_xref="PDB:3SLA"
/db_xref="PDB:3TX7"
/db_xref="PDB:4DJS"
/db_xref="PDB:6M90"
/db_xref="PDB:6M91"
/db_xref="PDB:6M92"
/db_xref="PDB:6M93"
/db_xref="PDB:6M94"
/db_xref="UniProtKB/Swiss-Prot:P35222"
/protein_id="CAA61107.1"
/translation="MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAP
SLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPET
LDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLL
NDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTL
HNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLA
GGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYE
KLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA
TKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRT
VLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIK
ATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRM
EEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQD
KEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSL
FRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMG
GHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL"
misc_feature 2573..2731
/note="alternatively spliced fragment"
BASE COUNT 880 a 707 c 822 g 953 t
ORIGIN
1 aagcctctcg gtctgtggca gcagcgttgg cccggccccg ggagcggaga gcgaggggag
61 gcggagacgg aggaaggtct gaggagcagc ttcagtcccc gccgagccgc caccgcaggt
121 cgaggacggt cggactcccg cggcgggagg agcctgttcc cctgagggta tttgaagtat
181 accatacaac tgttttgaaa atccagcgtg gacaatggct actcaagctg atttgatgga
241 gttggacatg gccatggaac cagacagaaa agcggctgtt agtcactggc agcaacagtc
301 ttacctggac tctggaatcc attctggtgc cactaccaca gctccttctc tgagtggtaa
361 aggcaatcct gaggaagagg atgtggatac ctcccaagtc ctgtatgagt gggaacaggg
421 attttctcag tccttcactc aagaacaagt agctgatatt gatggacagt atgcaatgac
481 tcgagctcag agggtacgag ctgctatgtt ccctgagaca ttagatgagg gcatgcagat
541 cccatctaca cagtttgatg ctgctcatcc cactaatgtc cagcgtttgg ctgaaccatc
601 acagatgctg aaacatgcag ttgtaaactt gattaactat caagatgatg cagaacttgc
661 cacacgtgca atccctgaac tgacaaaact gctaaatgac gaggaccagg tggtggttaa
721 taaggctgca gttatggtcc atcagctttc taaaaaggaa gcttccagac acgctatcat
781 gcgttctcct cagatggtgt ctgctattgt acgtaccatg cagaatacaa atgatgtaga
841 aacagctcgt tgtaccgctg ggaccttgca taacctttcc catcatcgtg agggcttact
901 ggccatcttt aagtctggag gcattcctgc cctggtgaaa atgcttggtt caccagtgga
961 ttctgtgttg ttttatgcca ttacaactct ccacaacctt ttattacatc aagaaggagc
1021 taaaatggca gtgcgtttag ctggtgggct gcagaaaatg gttgccttgc tcaacaaaac
1081 aaatgttaaa ttcttggcta ttacgacaga ctgccttcaa attttagctt atggcaacca
1141 agaaagcaag ctcatcatac tggctagtgg tggaccccaa gctttagtaa atataatgag
1201 gacctatact tacgaaaaac tactgtggac cacaagcaga gtgctgaagg tgctatctgt
1261 ctgctctagt aataagccgg ctattgtaga agctggtgga atgcaagctt taggacttca
1321 cctgacagat ccaagtcaac gtcttgttca gaactgtctt tggactctca ggaatctttc
1381 agatgctgca actaaacagg aagggatgga aggtctcctt gggactcttg ttcagcttct
1441 gggttcagat gatataaatg tggtcacctg tgcagctgga attctttcta acctcacttg
1501 caataattat aagaacaaga tgatggtctg ccaagtgggt ggtatagagg ctcttgtgcg
1561 tactgtcctt cgggctggtg acagggaaga catcactgag cctgccatct gtgctcttcg
1621 tcatctgacc agccgacacc aagaagcaga gatggcccag aatgcagttc gccttcacta
1681 tggactacca gttgtggtta agctcttaca cccaccatcc cactggcctc tgataaaggc
1741 tactgttgga ttgattcgaa atcttgccct ttgtcccgca aatcatgcac ctttgcgtga
1801 gcagggtgcc attccacgac tagttcagtt gcttgttcgt gcacatcagg atacccagcg
1861 ccgtacgtcc atgggtggga cacagcagca atttgtggag ggggtccgca tggaagaaat
1921 agttgaaggt tgtaccggag cccttcacat cctagctcgg gatgttcaca accgaattgt
1981 tatcagagga ctaaatacca ttccattgtt tgtgcagctg ctttattctc ccattgaaaa
2041 catccaaaga gtagctgcag gggtcctctg tgaacttgct caggacaagg aagctgcaga
2101 agctattgaa gctgagggag ccacagctcc tctgacagag ttacttcact ctaggaatga
2161 aggtgtggcg acatatgcag ctgctgtttt gttccgaatg tctgaggaca agccacaaga
2221 ttacaagaaa cggctttcag ttgagctgac cagctctctc ttcagaacag agccaatggc
2281 ttggaatgag actgctgatc ttggacttga tattggtgcc cagggagaac cccttggata
2341 tcgccaggat gatcctagct atcgttcttt tcactctggt ggatatggcc aggatgcctt
2401 gggtatggac cccatgatgg aacatgagat gggtggccac caccctggtg ctgactatcc
2461 agttgatggg ctgccagatc tggggcatgc ccaggacctc atggatgggc tgcctccagg
2521 tgacagcaat cagctggcct ggtttgatac tgacctgtaa atcatccttt agctgtattg
2581 tctgaacttg cattgtgatt ggcctgtaga gttgctgaga gggctcgagg ggtgggctgg
2641 tatctcagaa agtgcctgac acactaacca agctgagttt cctatgggaa caattgaagt
2701 aaactttttg ttctggtcct ttttggtcga ggagtaacaa tacaaatgga ttttgggagt
2761 gactcaagaa gtgaagaatg cacaagaatg gatcacaaga tggaatttag caaaccctag
2821 ccttgcttgt taaaattttt tttttttttt ttttaagaat atctgtaatg gtactgactt
2881 tgcttgcttt gaagtagctc tttttttttt tttttttttt tttttttgca gtaactgttt
2941 tttaagtctc tcgtagtgtt aagttatagt gaatactgct acagcaattt ctaattttta
3001 agaattgagt aatggtgtag aacactaatt aattcataat cactctaatt aattgtaatc
3061 tgaataaagt gtaacaattg tgtagccttt ttgtataaaa tagacaaata gaaaatggtc
3121 caattagttt cctttttaat atgcttaaaa taagcaggtg gatctatttc atgtttttga
3181 tcaaaaacta tttgggatat gtatgggtag ggtaaatcag taagaggtgt tatttggaac
3241 cttgttttgg acagtttacc agttgccttt tatcccaaag ttgttgtaac ctgctgtgat
3301 acgatgcttc aagagaaaat gcggttataa aaaatggttc agaattaaac ttttaattca
3361 tt
//