LOCUS X82850 1316 bp mRNA linear HUM 18-APR-2005
DEFINITION H.sapiens mRNA for thyroid transcript factor 1.
ACCESSION X82850
VERSION X82850.1
KEYWORDS thiroid transcription factor 1; TTF-1 gene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Saiardi A., Tassi V., De Filippis V., Civitareale D.
TITLE Cloning and sequence analysis of human thyroid transcription factor
1
JOURNAL Biochim. Biophys. Acta 1261(2), 307-310(1995).
PUBMED 7711080
REFERENCE 2 (bases 1 to 1316)
AUTHORS Civitareale D.
JOURNAL Submitted (21-NOV-1994) to the INSDC. D. Civitareale, CMNS /
IRCCS-CSS, Via Nazionale 66030, S. Maria Imbaro, ITALY
FEATURES Location/Qualifiers
source 1..1316
/db_xref="H-InvDB:HIT000323934"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="9"
/tissue_type="thyroid carcinoma"
/db_xref="taxon:9606"
CDS 15..1130
/gene="TTF-1"
/product="thyroid transcription factor 1"
/db_xref="GOA:P43699"
/db_xref="H-InvDB:HIT000323934.15"
/db_xref="HGNC:HGNC:11825"
/db_xref="InterPro:IPR001356"
/db_xref="InterPro:IPR009057"
/db_xref="InterPro:IPR017970"
/db_xref="InterPro:IPR020479"
/db_xref="UniProtKB/Swiss-Prot:P43699"
/protein_id="CAA58053.1"
/translation="MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQG
QAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELPPYQD
TMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPSAP
RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR
QAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPA
PGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAHHA
ASPAALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW"
misc_feature 612..684
/note="homeobox"
BASE COUNT 249 a 477 c 433 g 157 t
ORIGIN
1 gccgccgccg aatcatgtcg atgagtccaa agcacacgac tccgttctca gtgtctgaca
61 tcttgagtcc cctggaggaa agctacaaga aagtgggcat ggagggcggc ggcctcgggg
121 ctccgctggc ggcgtacagg cagggccagg cggcaccgcc aacagcggcc atgcagcagc
181 acgccgtggg gcaccacggc gccgtcaccg ccgcctacca catgacggcg gcgggggtgc
241 cccagctctc gcactccgcc gtggggggct actgcaacgg caacctgggc aacatgagcg
301 agctgccgcc gtaccaggac accatgagga acagcgcctc tggccccgga tggtacggcg
361 ccaacccaga cccgcgcttc cccgccatct cccgcttcat gggcccggcg agcggcatga
421 acatgagcgg catgggcggc ctgggctcgc tgggggacgt gagcaagaac atggccccgc
481 tgccaagcgc gccgcgcagg aagcgccggg tgctcttctc gcaggcgcag gtgtacgagc
541 tggagcgacg cttcaagcaa cagaagtacc tgtcggcgcc ggagcgcgag cacctggcca
601 gcatgatcca cctgacgccc acgcaggtca agatctggtt ccagaaccac cgctacaaaa
661 tgaagcgcca ggccaaggac aaggcggcgc agcagcaact gcagcaggac agcggcggcg
721 gcgggggcgg cgggggcacc gggtgcccgc agcagcaaca ggctcagcag cagtcgccgc
781 gacgcgtggc ggtgccggtc ctggtgaaag acggcaaacc gtgccaggcg ggtgcccccg
841 cgccgggcgc cgccagccta caaggccacg cgcagcagca ggcgcagcac caggcgcagg
901 ccgcgcaggc ggcggcagcg gccatctccg tgggcagcgg tggcgccggc cttggcgcac
961 acccgggcca ccagccaggc agcgcaggcc agtctccgga cctggcgcac cacgccgcca
1021 gccccgcggc gctgcagggc caggtatcca gcctgtccca cctgaactcc tcgggctcgg
1081 actacggcac catgtcctgc tccaccttgc tatacggtcg gacctggtga gaggacgccg
1141 ggccggccct agcccagcgc tctgcctcac cgcttccctc ctgcccgcca cacagaccac
1201 catccaccgc tgctccacgc gcttcgactt ttcttaacaa cctggccgcg tttagaccaa
1261 ggaacaaaaa aaccacaaag gccggaattc gagctcggta cccggggatc ctctag
//