LOCUS       X64436                   287 bp    DNA     linear   HUM 14-NOV-2006
DEFINITION  Homo sapiens HLA-DRB gene 5'region, HLA-DRB*0101 allele.
ACCESSION   X64436
VERSION     X64436.1
KEYWORDS    class II genes; class II major histocompatibility complex; HLA-DR
            Beta; HLA-DR Beta1; HLA-DRB genes; HLA-DRB*0101 gene;
            HLA-DRB1*0801.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Eliaou J.
  JOURNAL   Submitted (13-FEB-1992) to the INSDC. J. Eliaou, University
            Hospital / INSERM U291, Lab d'Immunologie, Hopital Saint Eloi,
            34059 Montpellier Cedex, FRANCE
REFERENCE   4  (bases 1 to 287)
  AUTHORS   Louis P., Eliaou J.F., Kerlan-Candon S., Pinet V., Vincent R.D.,
            Clot J.
  TITLE     Polymorphism in the regulatory region of HLA-DRB genes correlating
            with haplotype evolution
  JOURNAL   Immunogenetics 38(1), 21-26(1993).
   PUBMED   8462990
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Homo sapiens"
                     /chromosome="6"
                     /map="6p21.3"
                     /isolate="homozygous typing cell work shop number 9004"
                     /mol_type="genomic DNA"
                     /cell_line="Jesthom"
                     /cell_type="homozygous typing cells WS 9004"
                     /tissue_type="cultured B-lymphocytes"
                     /germline
                     /db_xref="taxon:9606"
     regulatory      1..141
                     /note="proximal promoter"
                     /regulatory_class="promoter"
     regulatory      15..29
                     /note="X box"
                     /regulatory_class="other"
     regulatory      49..58
                     /note="Y box"
                     /regulatory_class="other"
     regulatory      75..80
                     /regulatory_class="CAAT_signal"
     regulatory      112..117
                     /regulatory_class="TATA_box"
     sig_peptide     204..>287
                     /gene="HLA-DRB"
                     /allele="HLA-DRB*0101"
                     /product="MHC class II antigen"
     CDS             204..>287
                     /gene="HLA-DRB"
                     /allele="HLA-DRB*0101"
                     /product="MHC class II antigen"
                     /db_xref="UniProtKB/TrEMBL:A0N998"
                     /protein_id="CAL69438.1"
                     /translation="MVCLKLPGGSCMTALTVTLMVLSSRLAL"
     exon            <204..>287
                     /gene="HLA-DRB"
                     /allele="HLA-DRB*0101"
                     /number=1
BASE COUNT           60 a           78 c           73 g           76 t
ORIGIN      
        1 catacagcat ctctgaccag caactgatga tgctattgaa ctcagatgct gattggttct
       61 ccaacacgag attacccaac ccaggagcaa ggaaatcagt aacttcctcc ctataacttg
      121 gaatgtgggt ggaggggttc atagttctcc ctgagtgaga cttgcctgct tctctggccc
      181 ctggtcctgt cctgttctcc agcatggtgt gtctgaagct ccctggaggc tcctgcatga
      241 cagcgctgac agtgacactg atggtgctga gctcccgact ggctttg
//