LOCUS X15875 1647 bp mRNA linear HUM 12-SEP-1993
DEFINITION Human mRNA for cAMP response element (CRE-BP1) binding protein.
ACCESSION X15875
VERSION X15875.1
KEYWORDS CREBP1 gene; DNA binding protein; leucine zipper; transcription
factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1647)
AUTHORS Maekawa T., Sakura H., Kanei-Ishii C., Sudo T., Yoshimura T.,
Fujisawa J.I., Yoshida M., Ishii S.
TITLE Leucine zipper structure of the protein CRE-BP1 binding to the
cyclic AMP response element in brain
JOURNAL EMBO J. 8(7), 2023-2028(1989).
PUBMED 2529117
COMMENT Data kindly reviewed (20-FEB-1990) by Ishii S.
FEATURES Location/Qualifiers
source 1..1647
/db_xref="H-InvDB:HIT000321525"
/organism="Homo sapiens"
/mol_type="mRNA"
/dev_stage="foetus"
/clone_lib="lambda gt11"
/tissue_type="brain"
/db_xref="taxon:9606"
CDS 27..1544
/note="cAMP response element binding protein (AA 1-505)"
/db_xref="GOA:P15336"
/db_xref="H-InvDB:HIT000321525.13"
/db_xref="HGNC:HGNC:784"
/db_xref="InterPro:IPR004827"
/db_xref="InterPro:IPR013087"
/db_xref="InterPro:IPR016378"
/db_xref="InterPro:IPR029836"
/db_xref="InterPro:IPR036236"
/db_xref="PDB:1BHI"
/db_xref="PDB:1T2K"
/db_xref="PDB:4H36"
/db_xref="UniProtKB/Swiss-Prot:P15336"
/protein_id="CAA33886.1"
/translation="MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAV
HKHKHEMTLKFGPARNDSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASED
DIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPT
SAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLL
LHLPSGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKM
RLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPASPAHTTP
QTQSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNG
QLQSEVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDISVPSSPHTE
AIQHSSVSTSNGVSSTSKAEAVATSVLTQMADQSTEPALSQIVMAPSSQSQPSGS"
BASE COUNT 504 a 396 c 341 g 406 t
ORIGIN
1 gaattctgtg ataagttatt caacttatga aattcaagtt acatgtgaat tctgccaggc
61 aatacaagga cctgtggaat atgagtgatg acaaaccctt tctatgtact gcgcctggat
121 gtggccagcg ttttaccaac gaggatcatt tggctgtcca taaacataaa catgagatga
181 cactgaaatt tggtccagca cgtaatgaca gtgtcattgt ggctgatcag accccaacac
241 caacaagatt cttgaaaaac tgtgaagaag tgggtttgtt taatgagttg gcgagtccat
301 ttgagaatga attcaagaaa gcttcagaag atgacattaa aaaaatgcct ctagatttat
361 cccctcttgc aacacctatc ataagaagca aaattgagga gccttctgtt gtagaaacaa
421 ctcaccagga tagtccttta cctcacccag agtctactac cagtgatgag aaggaagtac
481 cattggcaca aactgcacag cccacatcag ctattgttcg tccagcatca ttacaggttc
541 ccaatgtgct gcttacaagt tctgactcaa gtgtaattat tcagcaggca gtaccttcac
601 caacctcaag tactgtaatc acccaggcac catcctctaa caggccaatt gtccctgtac
661 caggcccatt tcctcttctg ttacatcttc ctagtggaca aaccatgcct gttgctattc
721 ctgcatcaat tacaagttct aatgtgcatg ttccagctgc agtcccactc gttcgaccag
781 tcaccatggt gcctagtgtt ccaggaatcc caggtccttc ctctccccaa ccagtacagt
841 cagaagcaaa aatgagatta aaagctgctt tgacccagca acatcctcca gttaccaatg
901 gtgatactgt caaaggtcat ggtagcggat tggttaggac tcagtcagag gaatctcgac
961 cgcagtcatt acaacagcca gccacatcca ctacagaaac tccggcttct ccagctcaca
1021 caactccaca gacccaaagt acaagtggtc gtcggagaag agcagctaac gaagatcctg
1081 atgaaaaaag gagaaagttt ttagagcgaa atagagcagc agcttcaaga tgccgacaaa
1141 aaaggaaagt ctgggttcag tctttagaga agaaagctga agacttgagt tcattaaatg
1201 gtcagctgca gagtgaagtc accctgctga gaaatgaagt ggcacagctg aaacagcttc
1261 ttctggctca taaagattgc cctgtaaccg ccatgcagaa gaaatctggc tatcatactg
1321 ctgataaaga tgatagttca gaagacattt cagtgccgag tagtccacat acggaagcta
1381 tacagcatag ttcggtcagc acatccaatg gagtcagttc aacctccaag gcagaagctg
1441 tagccacttc agtcctcacc cagatggcgg accagagtac agagcctgct ctttcacaga
1501 tcgttatggc tccttcctcc cagtcacagc cctcaggaag ttgattaaaa acctgcagta
1561 caacagttta gatactcatt agtgacttca aagggaaatc aaggaaagac cagtttccat
1621 ttatgcgaaa tctgtggttg taaattt
//