LOCUS X15218 3511 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human ski oncogene mRNA.
ACCESSION X15218
VERSION X15218.1
KEYWORDS oncogene; ski oncogene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3511)
AUTHORS Nomura N.
JOURNAL Submitted (08-MAY-1989) to the INSDC. Nomura N., Molecular Oncology
Laboratory, Nippon Medical School, Sakuragi , 1-10-19 Uenosakuragi
Taito-ku, Tokyo 110, JAPAN.
REFERENCE 2 (bases 1 to 3511)
AUTHORS Nomura N., Sasamoto S., Ishii S., Matsui M., Ishizaki R.
TITLE Isolation of human cDNA clones of ski and the ski-related gene, sno
JOURNAL Nucleic Acids Res. 17(14), 5489-5500(1989).
PUBMED 2762147
COMMENT see x15217 and x15219 for ski-related mRNAs, snoA and snoN.
FEATURES Location/Qualifiers
source 1..3511
/db_xref="H-InvDB:HIT000321493"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_type="endothelial cells."
/tissue_type="umbilicord vein"
/db_xref="taxon:9606"
CDS 73..2259
/note="ski protein (AA 1 - 728)"
/db_xref="GOA:P12755"
/db_xref="H-InvDB:HIT000321493.15"
/db_xref="HGNC:HGNC:10896"
/db_xref="InterPro:IPR003380"
/db_xref="InterPro:IPR009061"
/db_xref="InterPro:IPR010919"
/db_xref="InterPro:IPR014890"
/db_xref="InterPro:IPR023216"
/db_xref="InterPro:IPR028760"
/db_xref="InterPro:IPR037000"
/db_xref="PDB:1MR1"
/db_xref="PDB:1SBX"
/db_xref="PDB:5XOD"
/db_xref="UniProtKB/Swiss-Prot:P12755"
/protein_id="CAA33288.1"
/translation="MEAAAGGRGCFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQ
EAYKKESAKEAGAAAVPAPVPAATEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCE
TVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHIYCSRCTADQLEI
LKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSV
RVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGF
DSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYGNKYKRRVPRVSSEPPASIRP
KTDDTSSQSPAPSEKDKPSSWLRTLAGSSNKSLGCVHPRQRLSAFRPWSPAVSASEKE
LSPHLPALIRDSFYSYKSFETAVAPNVALAPPAQQKVVSSPPCAAAVSRAPEPLATCT
QPRKRKLTVDTPGAPETLAPVAAPEEDKDSEAEVEVESREEFTSSLSSLSSPSFTSSS
SAKDLGSPGARALPSAVPDAAAPADAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEV
VKMRVKQEEKLSAALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENE
KKMKEANESRLRLKRELEQARQARVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADRE
QLRADLLREREAREHLEKVVKELQEQLWPRARPEAAGSEGAAELEP"
variation 3369..3369
/note="a is g in variant clone"
misc_feature 3373..3373
/note="3' end of variant clone with 7 additional A
residues"
misc_feature 3503..3508
/note="put. polyA signal"
BASE COUNT 663 a 1159 c 1089 g 600 t
ORIGIN
1 cggggcggcg gcgggggccg ggggggcccg ggcgcgcggg agcgggagcg gccgggggag
61 ccggagcgca ccatggaggc ggcggcaggc ggccgcggct gtttccagcc gcacccgggg
121 ctgcagaaga cgctggagca gttccacctg agctccatga gctcgctggg cggcccggcc
181 gctttctcgg cgcgctgggc gcaggaggcc tacaagaagg agagcgccaa ggaggcgggc
241 gcggccgcgg tgccggcgcc ggtgcccgca gccaccgagc cgccgcccgt gctgcacctg
301 cccgccatcc agccgccgcc gcccgtgctg cccgggccct tcttcatgcc gtccgaccgc
361 tccaccgagc gctgcgagac cgtactggaa ggcgagacca tctcgtgctt cgtggtggga
421 ggcgagaagc gcctgtgtct gccgcagatt ctcaactcgg tgctgcgcga cttctcgctg
481 cagcagatca acgcggtgtg cgacgagctc cacatctact gctcgcgctg cacggccgac
541 cagctggaga tcctcaaagt catgggcatc ctgcccttct cggcgccctc gtgcgggctc
601 atcaccaaga cggacgccga gcgcctgtgc aacgcgctgc tctacggcgg cgcctacccg
661 ccgccctgca agaaggagct ggccgccagc ctggcgctgg gcctggagct cagcgagcgc
721 agcgtccgcg tgtaccacga gtgcttcggc aagtgtaagg ggctgctggt gcccgagctc
781 tacagcagcc cgagcgccgc ctgcatccag tgcctggact gccgcctcat gtacccgccg
841 cacaagttcg tggtgcactc gcacaaggcc ctggagaacc ggacctgcca ctggggcttc
901 gactcggcca actggcgggc ctacatcctg ctgagccagg attacacggg caaggaggag
961 caggcgcgcc tcggccgctg cctggacgac gtgaaggaga aattcgacta tggcaacaag
1021 tacaagcggc gggtgccccg ggtctcctct gagcctccgg cctccataag acccaaaaca
1081 gatgacacct cttcccagtc ccccgcgcct tccgaaaagg acaagccgtc cagctggctg
1141 cggaccttgg ccggctcttc caataagagc ctgggctgtg ttcaccctcg ccagcgcctc
1201 tctgctttcc gaccctggtc ccccgcagtg tcagcgagtg agaaagagct ctccccacac
1261 ctcccggccc tcatccgaga cagcttctac tcctacaaga gctttgagac agccgtggcg
1321 cccaacgtgg ccctcgcacc gccggcccag cagaaggttg tgagcagccc tccgtgtgcc
1381 gccgccgtct cccgggcccc cgagcctctc gccacttgca cccagcctcg gaagcggaag
1441 ctgactgtgg acaccccagg agccccagag acgctggcgc ccgtggctgc cccagaggag
1501 gacaaggact cggaggcgga ggtggaagtt gaaagcaggg aggaattcac ctcctccttg
1561 tcctcgctct cttccccgtc ctttacctca tccagctccg ccaaggacct gggctccccg
1621 ggtgcgcgtg ccctgccctc ggccgtccct gatgctgcgg cccctgccga cgcccccagt
1681 gggctggagg cggagctgga gcacctgcgg caggcactgg agggcggcct ggacaccaag
1741 gaagccaaag agaagttcct gcatgaggtg gtcaagatgc gcgtgaagca ggaggagaag
1801 ctcagcgcag ccctgcaggc caagcgcagc ctccaccagg agctggagtt cctacgcgtg
1861 gccaagaagg agaagctgcg ggaggccacg gaggccaagc gtaacctgcg gaaggagatc
1921 gagcgtctcc gcgccgagaa cgagaagaag atgaaagagg ccaacgagtc acggctgcgc
1981 ctgaagcggg agctggagca ggcgcggcag gcccgggtgt gcgacaaggg ctgcgaggcg
2041 ggccgcctgc gcgccaagta ctcggcccag atcgaagacc tgcaggtgaa gctgcagcac
2101 gcggaggcgg accgggagca gctgcgggcc gacctgctgc gggagcgcga ggcccgggag
2161 cacctggaga aggtggtgaa ggagctgcag gaacagctgt ggccgcgggc ccgccccgag
2221 gctgcgggca gcgagggcgc tgcggagctg gagccgtaga ttccgtgcct gccgccgcag
2281 cgccgccgac aacgcgggtg caggggggcg cggctgggcg gtgcagctcc gcccggctcc
2341 gcccctgcag cccacacagc acaacgtctt accgtgccta ttaccaagcg agtgtttgta
2401 accatgtagt tttggaaccc actgcaaaat tttctactgg ccaagttcaa gtgagtaagc
2461 cgcgtccccc aactacagct ggagacgggg ccagctcggc ggcctgctgg tcctctgctt
2521 gctggaacat tctaacattt acacttttgt tataagctat ttaaaaccag taaggagact
2581 tgaaattcag aaaatcaaca catttttaaa tgactaactt ctaaaagccc caacacatga
2641 cgccatctga agacccgcaa cggagtgggg gtggcggccg ccccaccctc cccacccggg
2701 gaagccatca cagctcatct gcccgcggct gcgtgaggac agcaggggtt tttcttcaga
2761 gtctattttt tcagcgacaa ggacccaggt cttcctgctg ctgccaggga gagcagggac
2821 agtgccgcgt gcgagatgag ctcgaacact gcccgcctta ctgccgccta ccccgcccgc
2881 cacgccgccg tcgatgccag cgctgtcccc acgggtacca ggaagtgcag agccgcacag
2941 gagctgcccc ggagctgagg ggacggtctt cggctcctct gcaccccgtg attctgccca
3001 cgctcctcca ccacgaggca ctgacctgcg tcgggtggtg accgtggctg gcggtcacgc
3061 cctcagccct ccgggcacac gtgccgcctg accgggcgac ccttttcagt tcggcaaacg
3121 tcgctccctt cattttggga ctgaggctgc agcattggaa caaaagagca ttatttcaat
3181 ttttctttct ttttttttgt tcgttcattt aaacgtatat ttagaactgc actttgtcca
3241 caaccttccc ttctctttct attccccagt gaactgaggt ttttaccgac tttatagagc
3301 agtcaaatcc gaagtgctcg agtgcttaga aaccccctct ggtgcttggt tgaacaaggg
3361 aatcacaaaa aaacgaaaat gcaaaaactg aacttcgggg gtcgttctgt gccttccagc
3421 atcttgtaca gcaaatcctg actcgtgtct ttttaccccc aagatatctg tcttcagtag
3481 cgactgaatc tgccactctc agaataagtt c
//