LOCUS       HSU78735                6491 bp    mRNA    linear   HUM 06-FEB-1997
DEFINITION  Human ABC3 mRNA, complete cds.
ACCESSION   U78735
VERSION     U78735.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6491)
  AUTHORS   Connors,T.D., Van Raay,T.J., Petry,L.R., Klinger,K.W., Landes,G.M.
            and Burn,T.C.
  TITLE     The cloning of a human ABC gene (ABC3) mapping to chromosome
            16p13.3
  JOURNAL   Genomics 39 (2), 231-234 (1997)
   PUBMED   9027511
REFERENCE   2  (bases 1 to 6491)
  AUTHORS   Connors,T.D., Van Raay,T.J., Petry,L.R., Klinger,K.W., Landes,G.M.
            and Burn,T.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-NOV-1996) Human Genetics, Genzyme Genetics, One
            Mountain Road, Framinghan, MA 01701, USA
FEATURES             Location/Qualifiers
     source          1..6491
                     /db_xref="H-InvDB:HIT000221446"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..6491
                     /gene="ABC3"
     CDS             560..5674
                     /gene="ABC3"
                     /codon_start=1
                     /product="ABC3"
                     /protein_id="AAC50967.1"
                     /db_xref="GI:1699038"
                     /translation="MAVLRQLALLLWKNYTLQKRKVLVTVLELFLPLLFPGILIWLRL
                     KIQSENVPNATIYPGQSIQELPLFFTFPPPGDTWELAYIPSHSDAAKTVTETVRRALV
                     INMRVRGFPSEKDFEDYIRYDNCSSSVLAAVVFEHPFNHSKEPLPLAVKYHLRFSYTR
                     RNYMWTQTGSFFLKETEGWHTTSLFPLFPNPGPRELTSPDGGEPGYIREGFLAVQHAV
                     DRAIMEYHADAATRQLFQRLTVTIKRFPYPPFIADPFLVAIQYQLPLLLLLSFTYTAL
                     TIARAVVQEKERRLKEYMRMMGLSSWLHWSAWFLLFFLFLLIAASFMTLLFCVKVKPN
                     VAVLSRSDPSLVLAFLLCFAISTISFSFMVSTFFSKANMAAAFGGFLYFFTYIPYFFV
                     APRYNWMTLSQKLCSCLLSNVAMAMGAQLIGKFEAKGMGIQWRDLLSPVNVDDDFCFG
                     QVLGMLLLDSVLYGLVTWYMEAVFPGQFGVPQPWYFFIMPSYWCGKPRAVAGKEEEDS
                     DPEKALRNEYFEAEPEDLVAGIKIKHLSKVFRVGNKDRAAVRDLNLNLYEGQITVLLG
                     HNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDILFDNLTVA
                     EHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGIALIAG
                     SKVLILDEPTSGMDAISRRAIWDLLQRQKSDRTIVLTTHFMDEADLLGDRIAIMAKGE
                     LQCCGSSLFLKQKYGAGYHMTLVKEPHCNPEDISQLVHHHVPNATLESSAGAELSFIL
                     PRESTHRFEGLFAKLEKKQKELGIASFGASITTMEEVFLRVGKLVDSSMDIQAIQLPA
                     LQYQHERRASDWAVDSNLCGAMDPSDGIGALIEEERTAVKLNTGLALHCQQFWAMFLK
                     KAAYSWREWKMVAAQVLVPLTCVTLALLAINYSSELFDDPMLRLTLGEYGRTVVPFSV
                     PGTSQLGQQLSEHLKDALQAEGQEPREVLGDLEEFLIFRASVEGGGFNERCLVAASFR
                     DVGERTVVNALFNNQAYHSPATALAVVDNLLFKLLCGPHASIVVSNFPQPRSALQAAK
                     DQFNEGRKGFDIALNLLFAMAFLASTFSILAVSERAVQAKHVQFVSGVHVASFWLSAL
                     LWDLISFLIPSLLLLVVFKAFDVRAFTRDGHMADTLLLLLLYGWAIIPLMYLMNFFFL
                     GAATAYTRLTIFNILSGIATFLMVTIMRIPAVKLEELSKTLDHVFLVLPNHCLGMAVS
                     SFYENYETRRYCTSSEVAAHYCKKYNIQYQENFYAWSAPGVGRFVASMAASGCAYLIL
                     LFLIETNLLQRLRGILCALRRRRTLTELYTRMPVLPEDQDVADERTRILAPSPDSLLH
                     TPLIIKELSKVYEQRVPLLAVDRLSLAVQKGECFGLLGFNGAGKTTTFKMLTGEESLT
                     SGDAFVGGHRISSDVGKVRQRIGYCPQFDALLDHMTGREMLVMYARLRGIPERHIGAC
                     VENTLRGLLLEPHANKLVRTYSGGNKRKLSTGIALIGEPAVIFLDEPSTGMDPVARRL
                     LWDTVARARESGKAIIITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGSGYS
                     LRAKVQSEGQQEALEEFKAFVDLTFPGSVLEDEHQGMVHYHLPGRDLSWAKVFGILEK
                     AKEKYGVDDYSVSQISLEQVFLSFAHLQPPTAEEGR"
BASE COUNT         1304 a         2025 c         1858 g         1304 t
ORIGIN      
        1 ccgccccggc gcccaggctc ggtgctggag agtcatgcct gtgagccctg ggcacctcct
       61 gatgtcctgc gaggtcacgg tgttcccaaa cctcagggtt gccctgcccc actccagagg
      121 ctctcaggcc ccaccccgga gccctctgtg cggagccgcc tcctcctggc cagttcccca
      181 gtagtcctga agggagacct gctgtgtgga gcctcttctg ggacccagcc atgagtgtgg
      241 agctgagcaa ctgaacctga aactcttcca ctgtgagtca aggaggcttt tccgcacatg
      301 aaggacgctg agcgggaagg actcctctct gcctgcagtt gtagcgagtg gaccagcacc
      361 aggggctctc tagactgccc ctcctccatc gccttccctg cctctccagg acagagcagc
      421 cacgtctgca cacctcgccc tctttacact cagttttcag agcacgtttc tcctatttcc
      481 tgcgggttgc agcgcctact tgaacttact cagaccacct acttctctag cagcactggg
      541 cgtccctttc agcaagacga tggctgtgct caggcagctg gcgctcctcc tctggaagaa
      601 ctacaccctg cagaagcgga aggtcctggt gacggtcctg gaactcttcc tgccattgct
      661 gtttcctggg atcctcatct ggctccgctt gaagattcag tcggaaaatg tgcccaacgc
      721 caccatctac ccgggccagt ccatccagga gctgcctctg ttcttcacct tccctccgcc
      781 aggagacacc tgggagcttg cctacatccc ttctcacagt gacgctgcca agaccgtcac
      841 tgagacagtg cgcagggcac ttgtgatcaa catgcgagtg cgcggctttc cctccgagaa
      901 ggactttgag gactacatta ggtacgacaa ctgctcgtcc agcgtgctgg ccgccgtggt
      961 cttcgagcac cccttcaacc acagcaagga gcccctgccg ctggcggtga aatatcacct
     1021 acggttcagt tacacacgga gaaattacat gtggacccaa acaggctcct ttttcctgaa
     1081 agagacagaa ggctggcaca ctacttccct tttcccgctt ttcccaaacc caggaccaag
     1141 ggaactaaca tcccctgatg gcggagaacc tgggtacatc cgggaaggct tcctggccgt
     1201 gcagcatgct gtggaccggg ccatcatgga gtaccatgcc gatgccgcca cacgccagct
     1261 gttccagaga ctgacggtga ccatcaagag gttcccgtac ccgccgttca tcgcagaccc
     1321 cttcctcgtg gccatccagt accagctgcc cctgctgctg ctgctcagct tcacctacac
     1381 cgcgctcacc attgcccgtg ctgtcgtgca ggagaaggaa aggaggctga aggagtacat
     1441 gcgcatgatg gggctcagca gctggctgca ctggagtgcc tggttcctct tgttcttcct
     1501 cttcctcctc atcgccgcct ccttcatgac cctgctcttc tgtgtcaagg tgaagccaaa
     1561 tgtagccgtg ctgtcccgca gcgacccctc cctggtgctc gccttcctgc tgtgcttcgc
     1621 catctctacc atctccttca gcttcatggt cagcaccttc ttcagcaaag ccaacatggc
     1681 agcagccttc ggaggcttcc tctacttctt cacctacatc ccctacttct tcgtggcccc
     1741 tcggtacaac tggatgactc tgagccagaa gctctgctcc tgcctcctgt ctaatgtcgc
     1801 catggcaatg ggagcccagc tcattgggaa atttgaggcg aaaggcatgg gcatccagtg
     1861 gcgagacctc ctgagtcccg tcaacgtgga cgacgacttc tgcttcgggc aggtgctggg
     1921 gatgctgctg ctggactctg tgctctatgg cctggtgacc tggtacatgg aggccgtctt
     1981 cccagggcag ttcggcgtgc ctcagccctg gtacttcttc atcatgccct cctattggtg
     2041 tgggaagcca agggcggttg cagggaagga ggaagaagac agtgaccccg agaaagcact
     2101 cagaaacgag tactttgaag ccgagccaga ggacctggtg gcggggatca agatcaagca
     2161 cctgtccaag gtgttcaggg tgggaaataa ggacagggcg gccgtcagag acctgaacct
     2221 caacctgtac gagggacaga tcaccgtcct gctgggccac aacggtgccg ggaagaccac
     2281 caccctctcc atgctcacag gtctctttcc ccccaccagt ggacgggcat acatcagcgg
     2341 gtatgaaatt tcccaggaca tggttcagat ccggaagagc ctgggcctgt gcccgcagca
     2401 cgacatcctg tttgacaact tgacagtcgc agagcacctt tatttctacg cccagctgaa
     2461 gggcctgtca cgtcagaagt gccctgaaga agtcaagcag atgctgcaca tcatcggcct
     2521 ggaggacaag tggaactcac ggagccgctt cctgagcggg ggcatgaggc gcaagctctc
     2581 catcggcatc gccctcatcg caggctccaa ggtgctgata ctggacgagc ccacctcggg
     2641 catggacgcc atctccagga gggccatctg ggatcttctt cagcggcaga aaagtgaccg
     2701 caccatcgtg ctgaccaccc acttcatgga cgaggctgac ctgctgggag accgcatcgc
     2761 catcatggcc aagggggagc tgcagtgctg cgggtcctcg ctgttcctca agcagaaata
     2821 cggtgccggc tatcacatga cgctggtgaa ggagccgcac tgcaacccgg aagacatctc
     2881 ccagctggtc caccaccacg tgcccaacgc cacgctggag agcagcgctg gggccgagct
     2941 gtctttcatc cttcccagag agagcacgca caggtttgaa ggtctctttg ctaaactgga
     3001 gaagaagcag aaagagctgg gcattgccag ctttggggca tccatcacca ccatggagga
     3061 agtcttcctt cgggtcggga agctggtgga cagcagtatg gacatccagg ccatccagct
     3121 ccctgccctg cagtaccagc acgagaggcg cgccagcgac tgggctgtgg acagcaacct
     3181 ctgtggggcc atggacccct ccgacggcat tggagccctc atcgaggagg agcgcaccgc
     3241 tgtcaagctc aacactgggc tcgccctgca ctgccagcaa ttctgggcca tgttcctgaa
     3301 gaaggccgca tacagctggc gcgagtggaa aatggtggcg gcacaggtcc tggtgcctct
     3361 gacctgcgtc accctggccc tcctggccat caactactcc tcggagctct tcgacgaccc
     3421 catgctgagg ctgaccttgg gcgagtacgg cagaaccgtc gtgcccttct cagttcccgg
     3481 gacctcccag ctgggtcagc agctgtcaga gcatctgaaa gacgcactgc aggctgaggg
     3541 acaggagccc cgcgaggtgc tcggtgacct ggaggagttc ttgatcttca gggcttctgt
     3601 ggaggggggc ggctttaatg agcggtgcct tgtggcagcg tccttcagag atgtgggaga
     3661 gcgcacggtc gtcaacgcct tgttcaacaa ccaggcgtac cactctccag ccactgccct
     3721 ggccgtcgtg gacaaccttc tgttcaagct gctgtgcggg cctcacgcct ccattgtggt
     3781 ctccaacttc ccccagcccc ggagcgccct gcaggctgcc aaggaccagt ttaacgaggg
     3841 ccggaaggga ttcgacattg ccctcaacct gctcttcgcc atggcattct tggccagcac
     3901 gttctccatc ctggcggtca gcgagagggc cgtgcaggcc aagcatgtgc agtttgtgag
     3961 tggagtccac gtggccagtt tctggctctc tgctctgctg tgggacctca tctccttcct
     4021 catccccagt ctgctgctgc tggtggtgtt taaggccttc gacgtgcgtg ccttcacgcg
     4081 ggacggccac atggctgaca ccctgctgct gctcctgctc tacggctggg ccatcatccc
     4141 cctcatgtac ctgatgaact tcttcttctt gggggcggcc actgcctaca cgaggctgac
     4201 catcttcaac atcctgtcag gcatcgccac cttcctgatg gtcaccatca tgcgcatccc
     4261 agctgtaaaa ctggaagaac tttccaaaac cctggatcac gtgttcctgg tgctgcccaa
     4321 ccactgtctg gggatggcag tcagcagttt ctacgagaac tacgagacgc ggaggtactg
     4381 cacctcctcc gaggtcgccg cccactactg caagaaatat aacatccagt accaggagaa
     4441 cttctatgcc tggagcgccc cgggggtcgg ccggtttgtg gcctccatgg ccgcctcagg
     4501 gtgcgcctac ctcatcctgc tcttcctcat cgagaccaac ctgcttcaga gactcagggg
     4561 catcctctgc gccctccgga ggaggcggac actgacagaa ttatacaccc ggatgcctgt
     4621 gcttcctgag gaccaagatg tagcggacga gaggacccgc atcctggccc ccagcccgga
     4681 ctccctgctc cacacacctc tgattatcaa ggagctctcc aaggtgtacg agcagcgggt
     4741 gcccctcctg gccgtggaca ggctctccct cgcggtgcag aaaggggagt gcttcggcct
     4801 gctgggcttc aatggagccg ggaagaccac gactttcaaa atgctgaccg gggaggagag
     4861 cctcacttct ggggatgcct ttgtcggggg tcacagaatc agctctgatg tcggaaaggt
     4921 gcggcagcgg atcggctact gcccgcagtt tgatgccttg ctggaccaca tgacaggccg
     4981 ggagatgctg gtcatgtacg ctcggctccg gggcatccct gagcgccaca tcggggcctg
     5041 cgtggagaac actctgcggg gcctgctgct ggagccacat gccaacaagc tggtcaggac
     5101 gtacagtggt ggtaacaagc ggaagctgag caccggcatc gccctgatcg gagagcctgc
     5161 tgtcatcttc ctggacgagc cgtccactgg catggacccc gtggcccggc gcctgctttg
     5221 ggacaccgtg gcacgagccc gagagtctgg caaggccatc atcatcacct cccacagcat
     5281 ggaggagtgt gaggccctgt gcacccggct ggccatcatg gtgcaggggc agttcaagtg
     5341 cctgggcagc ccccagcacc tcaagagcaa gttcggcagc ggctactccc tgcgggccaa
     5401 ggtgcagagt gaagggcaac aggaggcgct ggaggagttc aaggccttcg tggacctgac
     5461 ctttccaggc agcgtcctgg aagatgagca ccaaggcatg gtccattacc acctgccggg
     5521 ccgtgacctc agctgggcga aggttttcgg tattctggag aaagccaagg aaaagtacgg
     5581 cgtggacgac tactccgtga gccagatctc gctggaacag gtcttcctga gcttcgccca
     5641 cctgcagccg cccaccgcag aggaggggcg atgaggggtg gcggctgtct cgccatcagg
     5701 cagggacagg acgggcaagc agggcccatc ttacatcctc tctctccaag tttatctcat
     5761 cctttatttt taatcacttt tttctatgat ggatatgaaa aattcaaggc agtatgcaca
     5821 gaatggacga gtgcagccca gccctcatgc ccaggatcag catgcgcatc tccatgtctg
     5881 catactctgg agttcacttt cccagagctg gggcaggccg ggcagtctgc gggcaagctc
     5941 cggggtctct gggtggagag ctgacccagg aagggctgca gctgagctgg gggttgaatt
     6001 tctccaggca ctccctggag agaggaccca gtgacttgtc caagtttaca cacgacacta
     6061 atctcccctg gggaggaagc gggaagccag ccaggttgaa ctgtagcgag gcccccaggc
     6121 cgccaggaat ggaccatgca gatcactgtc agtggaggga agctgctgac tgtgattagg
     6181 tgctggggtc ttagcgtcca gcgcagcccg ggggcatcct ggaggctctg ctcccttagg
     6241 gcatggtagt caccgcgaag ccgggcaccg tcccacagca tctcctagaa gcagccggca
     6301 caggagggaa ggtggccagg ctcgaagcag tctctgtttc cagcactgca ccctcaggaa
     6361 gtcgcccgcc ccaggacacg cagggaccac cctaagggct gggtggctgt ctcaaggaca
     6421 cattgaatac gttgtgacca tccagaaaat aaatgctgag gggacacaaa aaaaaaaaaa
     6481 aaaaaaaaaa a
//