LOCUS       HSU68068                 355 bp    mRNA    linear   HUM 24-JUL-2016
DEFINITION  Human estrogen receptor mRNA, alternatively spliced transcript H,
            partial cds.
VERSION     U68068.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Greene,G.L., Gilna,P., Waterfield,M., Baker,A., Hort,Y. and
  TITLE     Sequence and expression of human estrogen receptor complementary
  JOURNAL   Science 231 (4742), 1150-1154 (1986)
   PUBMED   3753802
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Green,S., Walter,P., Kumar,V., Krust,A., Bornert,J.M., Argos,P. and
  TITLE     Human oestrogen receptor cDNA: sequence, expression and homology to
  JOURNAL   Nature 320 (6058), 134-139 (1986)
   PUBMED   3754034
REFERENCE   3  (bases 1 to 335)
  AUTHORS   Keaveney,M., Klug,J., Dawson,M.T., Nestor,P.V., Neilan,J.G.,
            Forde,R.C. and Gannon,F.
  TITLE     Evidence for a previously unidentified upstream exon in the human
            oestrogen receptor gene
  JOURNAL   J. Mol. Endocrinol. 6 (1), 111-115 (1991)
   PUBMED   2015052
REFERENCE   4  (bases 1 to 335)
  AUTHORS   Piva,R., Gambari,R., Zorzato,F., Kumar,L. and del Senno,L.
  TITLE     Analysis of upstream sequences of the human estrogen receptor gene
  JOURNAL   Biochem. Biophys. Res. Commun. 183 (3), 996-1002 (1992)
   PUBMED   1567414
REFERENCE   5  (bases 1 to 335)
  AUTHORS   Keaveney,M., Klug,J. and Gannon,F.
  TITLE     Sequence analysis of the 5' flanking region of the human estrogen
            receptor gene
  JOURNAL   DNA Seq. 2 (6), 347-358 (1992)
   PUBMED   1476547
REFERENCE   6  (bases 1 to 335)
  AUTHORS   Piva,R., Bianchi,N., Aguiari,G.L., Gambari,R. and del Senno,L.
  TITLE     Sequencing of an RNA transcript of the human estrogen receptor
            gene: evidence for a new transcriptional event
  JOURNAL   J. Steroid Biochem. Mol. Biol. 46 (5), 531-538 (1993)
   PUBMED   8240974
REFERENCE   7  (bases 1 to 335)
  AUTHORS   Grandien,K.
  TITLE     Determination of transcription start sites in the human estrogen
            receptor gene and identification of a novel, tissue-specific,
            estrogen receptor-mRNA isoform
  JOURNAL   Mol. Cell. Endocrinol. 116 (2), 207-212 (1996)
   PUBMED   8647321
REFERENCE   8  (bases 1 to 355)
  AUTHORS   Thompson,D.A., McPherson,L.A., Carmeci,C., deConinck,E.C. and
  TITLE     Identification of two estrogen receptor transcripts with novel 5'
            exons isolated from a MCF7 cDNA library
  JOURNAL   J. Steroid Biochem. Mol. Biol. 62 (2-3), 143-153 (1997)
   PUBMED   9393949
REFERENCE   9  (bases 1 to 355)
  AUTHORS   Thompson,D.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-1996) Deparment of Surgery, Stanford University,
            MSLS Building, Room P228, 1201 Welch Rd., Stanford, CA 94305, USA
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Homo sapiens"
                     /tissue_type="breast adenocarcinoma"
     CDS             287..>355
                     /note="splice junction between nt 85/86, novel upstream
                     exon Ha splices to the novel exon Hb (which is
                     approximately 9 kb downstream from Ha in the genomic
                     sequence); splice junction between nt 216/217; novel
                     upstream exon Hb splices to nt 163; transcript H"
                     /product="estrogen receptor"
BASE COUNT           97 a          100 c           80 g           78 t
        1 aacaggctcg aaaggtccat gctcctttct cctgcccatt ctatagcata agaagacagt
       61 ctctgagtga taatcttctc ttcaagaaga agaaaactag gaaggagtaa gcacaaagat
      121 ctcttcacat tctccgggac tgcggtacca aatatcagca cagcacttct tgaaaaagga
      181 tgtagatttt aatctgaact ttgaaccatc actgaggtgg cccgccggtt tctgagcctt
      241 ctgccctgcg gggacacggt ctgcaccctg cccgcggcca cggaccatga ccatgaccct
      301 ccacaccaaa gcatctggga tggccctact gcatcagatc caagggaacg agctg