LOCUS HSU65019 1605 bp mRNA linear HUM 12-OCT-1996
DEFINITION Human MAD-related protein 2 (MADR2) mRNA, complete cds.
ACCESSION U65019
VERSION U65019.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1605)
AUTHORS Eppert,K., Scherer,S.W., Ozcelik,H., Pirone,R., Hoodless,P.,
Kim,H., Tsui,L.-C., Bapat,B., Gallinger,S., Andrulis,I.L.,
Thomsen,G.H., Wrana,J.L. and Attisano,L.
TITLE MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related
protein that is functionally mutated in colorectal carcinoma
JOURNAL Cell 86 (4), 543-552 (1996)
PUBMED 8752209
REFERENCE 2 (bases 1 to 1605)
AUTHORS Attisano,L., Pirone,R., Hoodless,P. and Wrana,J.L.
TITLE Direct Submission
JOURNAL Submitted (24-JUL-1996) Anatomy and Cell Biology, University of
Toronto, Medical Sciences Building, Toronto, Ontario M5S 1A8,
Canada
FEATURES Location/Qualifiers
source 1..1605
/db_xref="H-InvDB:HIT000220870"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q21"
gene 1..1605
/gene="MADR2"
CDS 37..1440
/gene="MADR2"
/codon_start=1
/product="MAD-related protein 2"
/protein_id="AAB17054.1"
/translation="MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKA
VKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLY
SFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIP
ETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCS
IAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGR
GVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA
LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
KVLTQMGSPSVRCSSMS"
BASE COUNT 477 a 342 c 361 g 419 t
ORIGIN
1 ttttcctagc gtggcttgct gcctttggtn aagaacatgt cgtccatctt gccattcacg
61 ccgccagttg tgaagagact gctgggatgg aagaagtcag ctggtgggtc tggaggagca
121 ggcggaggag agcagaatgg gcaggaagaa aagtggtgtg agaaagcagt gaaaagtctg
181 gtgaagaagc taaagaaaac aggacgatta gatgagcttg agaaagccat caccactcaa
241 aactgtaata ctaaatgtgt taccatacca agcacttgct ctgaaatttg gggactgagt
301 acaccaaata cgatagatca gtgggataca acaggccttt acagcttctc tgaacaaacc
361 aggtctcttg atggtcgtct ccaggtatcc catcgaaaag gattgccaca tgttatatat
421 tgccgattat ggcgctggcc tgatcttcac agtcatcatg aactcaaggc aattgaaaac
481 tgcgaatatg cttttaatct taaaaaggat gaagtatgtg taaaccctta ccactatcag
541 agagttgaga caccagtttt gcctccagta ttagtgcccc gacacaccga gatcctaaca
601 gaacttccgc ctctggatga ctatactcac tccattccag aaaacactaa cttcccagca
661 ggaattgagc cacagagtaa ttatattcca gaaacgccac ctcctggata tatcagtgaa
721 gatggagaaa caagtgacca acagttgaat caaagtatgg acacaggctc tccagcagaa
781 ctatctccta ctactctttc ccctgttaat catagcttgg atttacagcc agttacttac
841 tcagaacctg cattttggtg ttcgatagca tattatgaat taaatcagag ggttggagaa
901 accttccatg catcacagcc ctcactcact gtagatggct ttacagaccc atcaaattca
961 gagaggttct gcttaggttt actctccaat gttaaccgaa atgccacggt agaaatgaca
1021 agaaggcata taggaagagg agtgcgctta tactacatag gtggggaagt ttttgctgag
1081 tgcctaagtg atagtgcaat ctttgtgcag agccccaatt gtaatcagag atatggctgg
1141 caccctgcaa cagtgtgtaa aattccacca ggctgtaatc tgaagatctt caacaaccag
1201 gaatttgctg ctcttctggc tcagtctgtt aatcagggtt ttgaagccgt ctatcagcta
1261 actagaatgt gcaccataag aatgagtttt gtgaaagggt ggggagcaga ataccgaagg
1321 cagacggtaa caagtactcc ttgctggatt gaacttcatc tgaatggacc tctacagtgg
1381 ttggacaaag tattaactca gatgggatcc ccttcagtgc gttgctcaag catgtcataa
1441 agcttcacca atcaagtccc atggaaaaga cttaatgtaa caactcttct gttcattagc
1501 attgtgttgt ngtccctatg ggactgttta ctattccaaa agtttcaagg agagaaaaca
1561 gcanttgagg tctccntcat ttaaagnacc ctgtnggatt ttttt
//