LOCUS HSU62435 1743 bp mRNA linear HUM 11-JAN-1997
DEFINITION Human nicotinic acetylcholine receptor alpha6 subunit precursor,
mRNA, complete cds.
ACCESSION U62435
VERSION U62435.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1743)
AUTHORS Elliott,K.J., Ellis,S.B., Berckhan,K.J., Urrutia,A.,
Chavez-Noriega,L.E., Johnson,E.C., Velicelebi,G. and Harpold,M.M.
TITLE Comparative structure of human neuronal alpha 2-alpha 7 and beta
2-beta 4 nicotinic acetylcholine receptor subunits and functional
expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and
beta 4 subunits
JOURNAL J. Mol. Neurosci. 7 (3), 217-228 (1996)
PUBMED 8906617
REFERENCE 2 (bases 1 to 1743)
AUTHORS Elliott,K.J.
TITLE Direct Submission
JOURNAL Submitted (28-JUN-1996) Kathryn J. Elliott, SIBIA Neurosciences,
Inc., 505 Coast Blvd. So., La Jolla, CA 92037, USA
FEATURES Location/Qualifiers
source 1..1743
/db_xref="H-InvDB:HIT000220719"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="KEalpha6.3"
/tissue_type="Substantia nigra"
/clone_lib="Clontech #HL1179a, lambda gt10"
5'UTR 1..142
CDS 143..1627
/codon_start=1
/product="nicotinic acetylcholine receptor alpha6 subunit
precursor"
/protein_id="AAB40113.1"
/translation="MLTSKGQGFLHGGLCLWLCVFTPFFKGCVGCATEERLFHKLFSH
YNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEY
DGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPM
DITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDI
KYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCI
SVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTT
HTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHGEPRHL
KECFHCHKSNELATSKRRLSHQPLQWVVENSEHSPEVEDVINSVQFIAENMKSHNETK
EVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLLGNTGKS"
sig_peptide 143..232
mat_peptide 233..1624
/product="nicotinic acetylcholine receptor alpha6 subunit"
3'UTR 1628..1743
BASE COUNT 469 a 383 c 396 g 495 t
ORIGIN
1 cgggttttga tttctgagaa gacacacacg gattgcagtg ggcttctgat gatgtcaagg
61 ttggatgcat gtggctgact gatagctctt tgttttccac aatcctttgc ctaggaaaaa
121 ggaatccaag tgtgttttaa ccatgctgac cagcaagggg cagggattcc ttcatggggg
181 cttgtgtctc tggctgtgtg tgttcacacc tttctttaaa ggctgtgtgg gctgtgcaac
241 tgaggagagg ctcttccaca aactgttttc tcattacaac cagttcatca ggcctgtgga
301 aaacgtttcc gaccctgtca cggtacactt tgaagtggcc atcacccagc tggccaacgt
361 ggatgaagta aaccagatca tggaaaccaa tttgtggctg cgtcacatct ggaatgatta
421 taaattgcgc tgggatccaa tggaatatga tggcattgag actcttcgcg ttcctgcaga
481 taagatttgg aagcccgaca ttgttctcta taacaatgct gttggtgact tccaagtaga
541 aggcaaaaca aaagctcttc ttaaatacaa tggcatgata acctggactc caccagctat
601 ttttaagagt tcctgcccta tggatatcac ctttttccct tttgatcatc aaaactgttc
661 cctaaaattt ggttcctgga cgtatgacaa agctgaaatt gatcttctaa tcattggatc
721 aaaagtggat atgaatgatt tttgggaaaa cagtgaatgg gaaatcattg atgcctctgg
781 ctacaaacat gacatcaaat acaactgttg tgaagagata tacacagata taacctattc
841 tttctacatt agaagattgc cgatgtttta cacgattaat ctgatcatcc cttgtctctt
901 tatttcattt ctaaccgtgt tggtctttta ccttccttcg gactgtggtg aaaaagtgac
961 gctttgtatt tcagtcctgc tttctctgac tgtgtttttg ctggtcatca cagaaaccat
1021 cccatccaca tctctggtgg tcccactggt gggtgagtac ctgctgttca ccatgatctt
1081 tgtcacactg tccatcgtgg tgactgtgtt tgtgttgaac atacactacc gcaccccaac
1141 cacgcacaca atgcccaggt gggtgaagac agttttcctg aagctgctgc cccaggtcct
1201 gctgatgagg tggcctctgg acaagacaag gggcacaggc tctgatgcag tgcccagagg
1261 ccttgccagg aggcctgcca aaggcaagct tgcaagccat ggggaaccca gacatcttaa
1321 agaatgcttc cattgtcaca aatcaaatga gcttgccaca agcaagagaa gattaagtca
1381 tcagccatta cagtgggtgg tggaaaattc ggagcactcg cctgaagttg aagatgtgat
1441 taacagtgtt cagttcatag cagaaaacat gaagagccac aatgaaacca aggaggtaga
1501 agatgactgg aaatacgtgg ccatggtggt ggacagagta tttctttggg tatttataat
1561 tgtctgtgta tttggaactg cagggctatt tctacagcca ctacttggga acacaggaaa
1621 atcttaaaat gtattttctt ttatgttcag aaatttacag acaccatatt tgttctgcat
1681 tccctgccac aaggaaagga aagcaaaggc ttcccaccca agtcccccat ctgctaaaac
1741 ccg
//