LOCUS HSU43959 1284 bp mRNA linear HUM 31-JAN-1996
DEFINITION Human beta 4 adducin mRNA, alternatively spliced partial cds.
ACCESSION U43959
VERSION U43959.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1284)
AUTHORS Sinard,J.H., Stewart,G.W., Argent,A.C., Stabach,P.R. and
Morrow,J.S.
TITLE Characterization of a novel alternative transcript of beta adducin
JOURNAL Unpublished
REFERENCE 2 (bases 749 to 834)
AUTHORS Sinard,J.H., Stewart,G.W., Argent,A.C., Gilligan,D.M. and
Morrow,J.S.
TITLE A novel isoform of beta adducin utilizes an alternatively spliced
exon near the C-terminus
JOURNAL Mol. Biol. Cell 6 (Suppl), 269-269 (1995)
REFERENCE 3 (bases 1 to 1284)
AUTHORS Morrow,J.S.
TITLE Direct Submission
JOURNAL Submitted (26-DEC-1995) Jon S. Morrow, Pathology, Yale University
School of Medicine, 333, Cedar Street, New Haven, CT 06510, USA
FEATURES Location/Qualifiers
source 1..1284
/db_xref="H-InvDB:HIT000219907"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="bone marrow"
/dev_stage="adult"
CDS <1..939
/note="COOH-terminal fragment; alternatively spliced form"
/codon_start=1
/product="beta 4 adducin"
/protein_id="AAA86421.1"
/translation="LEQEKHRPHEVGSVQWAGSTFGPMQKSRLGEHEFEALMRMLDNL
GYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRW
LNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTD
PQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDS
EETVPNPFSQLTDQELEEYKKEVERKKLELDETGQEREPGSGPAVCEFFSVALHIWSN
ILERKKLPQKSLAHLQSLHLLLQCRAQRRRQRQRAL"
exon 749..834
/product="beta 4 adducin"
/note="sequence downstream of this exon is frame-shifted"
BASE COUNT 373 a 344 c 374 g 193 t
ORIGIN
1 ctggagcagg agaagcaccg gccccatgag gtgggctccg tgcagtgggc cgggagcacc
61 tttgggccta tgcagaagag tcggctgggg gagcatgagt ttgaggccct catgaggatg
121 ctggacaacc tgggctacag aacaggttac acgtatcgcc acccctttgt tcaagagaaa
181 accaaacaca aaagtgaggt ggagattcca gccacggtca cagccttcgt gtttgaggag
241 gacggtgccc cggtgcccgc cctgcgacag catgcccaga agcagcagaa ggagaagacc
301 cgctggctca atacgcccaa cacctacctg cgggtcaatg tggccgatga ggtccagagg
361 agcatgggca gcccccgacc caagaccacg tggatgaagg ctgacgaggt ggagaaatcc
421 agcagtggca tgccgattcg catcgaaaac ccaaaccaat ttgtgcctct ctatactgac
481 ccccaggaag tactggagat gaggaacaag attcgagaac aaaaccgaca agatgtgaag
541 tcagcggggc ctcagtccca gctcctggcg agcgtcattg ccgagaagag ccgaagcccg
601 tctacagaga gccagctgat gtccaaggga gacgaggata ccaaagacga ttcagaggag
661 acggtgccca accccttcag ccaactcact gaccaggagt tggaggagta caagaaagag
721 gtggagagga agaaactaga acttgatgag acaggacagg aacgagagcc aggctctggt
781 ccggccgtgt gcgagttctt cagcgttgcc ctccacatct ggagtaacat attggagaga
841 aagaaactgc cccagaagag cctggctcac ctgcaaagtc tgcacctgct tctccagtgc
901 agagcccagc gaaggaggca gagacaaaga gccctttagt ctctccttcc aagtctttag
961 aggaaggtac taagaagaca gaaacaagca aagccgccac cacagagccc gaaacaaccc
1021 agccggaagg ggtggtggtc aacgggaggg aggaggagca gacggcagag gaaatcctca
1081 gcaaaggcct gagccagatg accaccagtg ctgacacgga tgttgatacc tctaaggaca
1141 aaaccgagtc ggtcaccagc ggccccatgt ccccagaggg ctcaccttcc aagtctccct
1201 caaagaagaa aaagaaattc cgaaccccct ccttcctgaa aaagagcaaa aagaaggaga
1261 aagtggagtc ctgattcatg acac
//