LOCUS       HSU31202                1557 bp    DNA     linear   HUM 13-DEC-1995
DEFINITION  Human noggin (NOGGIN) gene, complete cds.
ACCESSION   U31202
VERSION     U31202.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1557)
  AUTHORS   Valenzuela,D.M., Economides,A.N., Rojas,E., Lamb,T.M., Nunez,L.,
            Jones,P., Ip,N.Y., Espinosa,R., Brannan,C.I., Gilbert,D.J.,
            Copeland,N.G., Jenkins,N.A., LeBeau,M.M., Harland,R.M. and
            Yancopoulos,G.D.
  TITLE     Identification of mammalian noggin and its expression in the adult
            nervous system
  JOURNAL   J. Neurosci. 15 (9), 6077-6084 (1995)
   PUBMED   7666191
REFERENCE   2  (bases 1 to 1557)
  AUTHORS   Valenzuela,D.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUL-1995) David M. Valenzuela, Discovery Group,
            Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Rd.,
            Tarrytown, NY 10591, USA
FEATURES             Location/Qualifiers
     source          1..1557
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q22"
     gene            812..1510
                     /gene="NOGGIN"
     CDS             812..1510
                     /gene="NOGGIN"
                     /codon_start=1
                     /product="noggin"
                     /protein_id="AAA83259.1"
                     /db_xref="GI:1117817"
                     /translation="MERCPSLGVTLYALVVVLGLRATPAGGQHYLHIRPAPSDNLPLV
                     DLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGAAGGAEDLA
                     ELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYA
                     WNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWI
                     PIQYPIISECKCSC"
BASE COUNT          242 a          521 c          580 g          213 t
ORIGIN      
        1 gagctccggc gggtcagccg gactgtcggc ttcccggggc atctgggtcc ggcggggcac
       61 agccctgggc gctgccgaag ccgccgccgc cgcctccgcg gcgagtacag gcggcttccc
      121 ccggagcctg tgcagctcca gctcctcggg ggtggagaag tggggggtgg gggtgatgta
      181 tggggggaag aagggggagg ggccaacccc gagagagtca gtggtttcca tggtgatgga
      241 gctgaaagtg caggaaattt aaaggcttgg accctgcgag acagacaaac cggtgccaac
      301 gtgcgcggac gccgccgccg ccgccgccgc tggagtccgc cgggcagagc cggccgcgga
      361 gcccggagca ggcggaggga agtgccccta gaaccagctc agccagcggc gcttgcacag
      421 agcggccggn cgaagagcag cgagaggagg aggggagagc ggctcgtcca cgcgccctgc
      481 gccgccgccg gcccgggaag gcagcgagga gccggcgcct cccgcgcccc gcggtcgccc
      541 tggagtaatt tcggatgccc agccgcggcc gccttcccca gtagacccgg gagaggagtt
      601 gcggccaact tgtgtgcctt tcttccgccc cggtgggagc cggcgctgcg cgaagggctc
      661 tcccggcggc tcatgctgcc ggccctgcgc ctgcccagcc tcgggtgagc cgcctccgga
      721 gagacggggg agcgcggcgg cgccgcgggc tcggcgtgct ctcctccggg gacgcgggac
      781 gaagcagcag ccccgggcgc gcgccagagg catggagcgc tgccccagcc taggggtcac
      841 cctctacgcc ctggtggtgg tcctggggct gcgggcgaca ccggccggcg gccagcacta
      901 tctccacatc cgcccggcac ccagcgacaa cctgcccctg gtggacctca tcgaacaccc
      961 agaccctatc tttgacccca aggaaaagga tctgaacgag acgctgctgc gctcgctgct
     1021 cgggggccac tacgacccag gcttcatggc cacctcgccc cccgaggacc ggcccggcgg
     1081 gggcgggggt gcagctgggg gcgcggagga cctggcggag ctggaccagc tgctgcggca
     1141 gcggccgtcg ggggccatgc cgagcgagat caaagggcta gagttctccg agggcttggc
     1201 ccagggcaag aagcagcgcc taagcaagaa gctgcggagg aagttacaga tgtggctgtg
     1261 gtcgcagaca ttctgccccg tgctgtacgc gtggaacgac ctgggcagcc gcttttggcc
     1321 gcgctacgtg aaggtgggca gctgcttcag taagcgctcg tgctccgtgc ccgagggcat
     1381 ggtgtgcaag ccgtccaagt ccgtgcacct cacggtgctg cggtggcgct gtcagcggcg
     1441 cgggggccag cgctgcggct ggattcccat ccagtacccc atcatttccg agtgcaagtg
     1501 ctcgtgctag aactcggggg ccccctgccc gcacccggac acttgatcct cgagctc
//