LOCUS       HSU25414                1265 bp    DNA     linear   HUM 10-SEP-2007
DEFINITION  Human annexin I (ANX1) gene, promoter region and exon 1.
ACCESSION   U25414
VERSION     U25414.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1265)
  AUTHORS   Morgan,R.O. and Fernandez,M.P.
  TITLE     A BC200-derived element and Z-DNA as structural markers in annexin
            I genes: relevance to Alu evolution and annexin tetrad formation
  JOURNAL   J. Mol. Evol. 41 (6), 979-985 (1995)
   PUBMED   8587144
REFERENCE   2  (bases 1 to 1265)
  AUTHORS   Fernandez,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-1995) Maria-Pilar Fernandez, University of
            Oviedo, Functional Biology (Biochem. Mol. Biol.), c/Julian Claveria
            6, E-33006 Oviedo, Spain
FEATURES             Location/Qualifiers
     source          1..1265
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /map="9q12-9q22"
                     /clone="lambda 28p11 (Biogen)"
                     /cell_type="fibroblast"
     regulatory      <1..999
                     /regulatory_class="promoter"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /function="gene expression regulation"
     repeat_region   373..388
                     /note="5'-flanking direct repeat; 16 bp insertion site
                     (A-rich recombination target)"
                     /rpt_type=direct
     repeat_region   389..532
                     /note="short interspersed repetitive element; ANX1-BC200;
                     probable retroposon of Alu-like segment from active BC200
                     gene, descendent of 7SL gene and phylogenetically close to
                     free left Alu-C monomer (FLAM-C)"
                     /rpt_family="Alu (BC200)"
                     /rpt_type=dispersed
     repeat_region   533..548
                     /note="3'-flanking direct repeat; 16 bp insertion site"
                     /rpt_type=direct
     repeat_region   736..787
                     /note="contains 2 identical copies of 20 bp tandem repeat"
                     /rpt_type=tandem
                     /rpt_unit_range=736..755
     regulatory      969..976
                     /regulatory_class="TATA_box"
                     /note="31 bp 5' of putative transcription start point"
     gene            1000..1059
                     /gene="ANX1"
     exon            1000..1059
                     /gene="ANX1"
                     /product="annexin I"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phospholipase A2 inhibitor; lipocortin 1; first of
                     13 exons"
                     /number=1
     intron          1060..>1265
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /number=1
BASE COUNT          422 a          190 c          225 g          428 t
ORIGIN      
        1 tgtatcaata tgatatataa ctgatctata ttacagttat atatatagtt ctatgtaact
       61 gactctattt aaaagaatta atgtagatag gccttctgat gtcaatgctt ttattgaatg
      121 tcataatgat caaatttttg gcattacctt tgttcaaaat tttgagccaa tctggaactt
      181 tattacttct atatttctta tttataacaa caagctatat ctaggaacaa aagtcgttta
      241 ttttttaagg caagaaaaat ataaatagaa aattattcgg cactgtgtaa tgttaaaatt
      301 tacaaatata tgttatttct ccattgtcac aagaattcta gtgggtagac aacttagata
      361 atgctcctat atacaaaagt aaaaacagct aggcatggtg gctcacgcct gtgattccaa
      421 ctcttaggga gacagaggca ggaggatagc ctgagcccag gagtttgaga cctgcctggg
      481 caatataacg agaccccatt ctccacaaaa agcgggggaa aaagacaaca aaacaaaagt
      541 aaaaacaggt tcagaaaaat taagtatgtc cctaaagtca cagaataata agtgatggag
      601 gtggaattca aatgtaatat tttgtttgtt ggtttgttta gttttgaagg taacatactt
      661 tttagtctac aacctattta actacaaaag tgtgccaatc actggtatta ggattggggc
      721 agatgtatac tctgaaaata aaagtgcaaa ataaatatcc catctggaaa taaaagtgca
      781 aaataaagag ggaggaaaaa tcagcccttc catttctttt cctttgtaat gccagttgaa
      841 ttggtttagt gagtagtttt gcaagacttg tttcactttg tttttggaca tagctgagcc
      901 atgtacttca aacagaaggc agccaattac taacttctgg ttgctaggtg tggcttcctt
      961 taaaatccta taaaatcaga agcccaagtc tccactgcca gtgtgaaatc ttcagagaag
     1021 aatttctctt tagttctttg caagaaggta gagataaagg taagtcttgg ttttcctttt
     1081 agttagtttt ggttgttttg aaaacttttc tcatcactat gttaaatgtt actgcttcta
     1141 caggatttat ggttagttgc atttaacatg ataagtcatt cataaatctt tctgtagaat
     1201 tacattggat atttatattt taggaatcac aaattacaat atttttgttc tacttagtta
     1261 caaat
//