LOCUS HSU09278 2778 bp mRNA linear HUM 14-NOV-2016
DEFINITION Human fibroblast activation protein mRNA, complete cds.
ACCESSION U09278
VERSION U09278.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2778)
AUTHORS Scanlan,M.J., Raj,B.K., Calvo,B., Garin-Chesa,P.,
Sanz-Moncasi,M.P., Healey,J.H., Old,L.J. and Rettig,W.J.
TITLE Molecular cloning of fibroblast activation protein alpha, a member
of the serine protease family selectively expressed in stromal
fibroblasts of epithelial cancers
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 91 (12), 5657-5661 (1994)
PUBMED 7911242
REFERENCE 2 (bases 1 to 2778)
AUTHORS Rettig,W.J.
TITLE Direct Submission
JOURNAL Submitted (29-APR-1994) Wolfgang J. Rettig, Thomae GmbH, Oncology,
Birkendorfer Str. 65, D88397 Biberach, Germany
REFERENCE 3 (bases 1 to 2778)
AUTHORS Rettig,W.J.
TITLE Direct Submission
JOURNAL Submitted (14-MAR-1997) Thomae GmbH, Oncology, Birkendorfer Str.
65, D88397 Biberach, Germany
REMARK Sequence update by submitter
REFERENCE 4 (bases 1 to 2778)
AUTHORS Rettig,W.J.
TITLE Direct Submission
JOURNAL Submitted (14-NOV-2016) Thomae GmbH, Oncology, Birkendorfer Str.
65, D88397 Biberach, Germany
REMARK Sequence update by database staff to remove vector contamination
COMMENT On Nov 14, 2016 this sequence version replaced U09278.1.
FEATURES Location/Qualifiers
source 1..2778
/db_xref="H-InvDB:HIT000217896"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="fibroblast"
CDS 209..2491
/codon_start=1
/product="fibroblast activation protein"
/protein_id="AAB49652.1"
/translation="MKTWVKIVFGVATSAVLALLVMCIVLRPSRVHNSEENTMRALTL
KDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNASN
YGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGS
KLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLPTKYALWWSPNG
KFLAYAEFNDKDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVG
PQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPK
TQEHIEESRTGWAGGFFVSRPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITS
GKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQY
YTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEI
KKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEG
MVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWS
YGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTV
MARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLS
TNHLYTHMTHFLKQCFSLSD"
BASE COUNT 906 a 518 c 557 g 797 t
ORIGIN
1 aagaacgccc ccaaaatctg tttctaattt tacagaaatc ttttgaaact tggcacggta
61 ttcaaaagtc cgtggaaaga aaaaaacctt gtcctggctt cagcttccaa ctacaaagac
121 agacttggtc cttttcaacg gttttcacag atccagtgac ccacgctctg aagacagaat
181 tagctaactt tcaaaaacat ctggaaaaat gaagacttgg gtaaaaatcg tatttggagt
241 tgccacctct gctgtgcttg ccttattggt gatgtgcatt gtcttacgcc cttcaagagt
301 tcataactct gaagaaaata caatgagagc actcacactg aaggatattt taaatggaac
361 attttcttat aaaacatttt ttccaaactg gatttcagga caagaatatc ttcatcaatc
421 tgcagataac aatatagtac tttataatat tgaaacagga caatcatata ccattttgag
481 taatagaacc atgaaaagtg tgaatgcttc aaattacggc ttatcacctg atcggcaatt
541 tgtatatcta gaaagtgatt attcaaagct ttggagatac tcttacacag caacatatta
601 catctatgac cttagcaatg gagaatttgt aagaggaaat gagcttcctc gtccaattca
661 gtatttatgc tggtcgcctg ttgggagtaa attagcatat gtctatcaaa acaatatcta
721 tttgaaacaa agaccaggag atccaccttt tcaaataaca tttaatggaa gagaaaataa
781 aatatttaat ggaatcccag actgggttta tgaagaggaa atgcttccta caaaatatgc
841 tctctggtgg tctcctaatg gaaaattttt ggcatatgcg gaatttaatg ataaggatat
901 accagttatt gcctattcct attatggcga tgaacaatat cctagaacaa taaatattcc
961 atacccaaag gctggagcta agaatcccgt tgttcggata tttattatcg ataccactta
1021 ccctgcgtat gtaggtcccc aggaagtgcc tgttccagca atgatagcct caagtgatta
1081 ttatttcagt tggctcacgt gggttactga tgaacgagta tgtttgcagt ggctaaaaag
1141 agtccagaat gtttcggtcc tgtctatatg tgacttcagg gaagactggc agacatggga
1201 ttgtccaaag acccaggagc atatagaaga aagcagaact ggatgggctg gtggattctt
1261 tgtttcaaga ccagttttca gctatgatgc catttcgtac tacaaaatat ttagtgacaa
1321 ggatggctac aaacatattc actatatcaa agacactgtg gaaaatgcta ttcaaattac
1381 aagtggcaag tgggaggcca taaatatatt cagagtaaca caggattcac tgttttattc
1441 tagcaatgaa tttgaagaat accctggaag aagaaacatc tacagaatta gcattggaag
1501 ctatcctcca agcaagaagt gtgttacttg ccatctaagg aaagaaaggt gccaatatta
1561 cacagcaagt ttcagcgact acgccaagta ctatgcactt gtctgctacg gcccaggcat
1621 ccccatttcc acccttcatg atggacgcac tgatcaagaa attaaaatcc tggaagaaaa
1681 caaggaattg gaaaatgctt tgaaaaatat ccagctgcct aaagaggaaa ttaagaaact
1741 tgaagtagat gaaattactt tatggtacaa gatgattctt cctcctcaat ttgacagatc
1801 aaagaagtat cccttgctaa ttcaagtgta tggtggtccc tgcagtcaga gtgtaaggtc
1861 tgtatttgct gttaattgga tatcttatct tgcaagtaag gaagggatgg tcattgcctt
1921 ggtggatggt cgaggaacag ctttccaagg tgacaaactc ctctatgcag tgtatcgaaa
1981 gctgggtgtt tatgaagttg aagaccagat tacagctgtc agaaaattca tagaaatggg
2041 tttcattgat gaaaaaagaa tagccatatg gggctggtcc tatggaggat acgtttcatc
2101 actggccctt gcatctggaa ctggtctttt caaatgtggt atagcagtgg ctccagtctc
2161 cagctgggaa tattacgcgt ctgtctacac agagagattc atgggtctcc caacaaagga
2221 tgataatctt gagcactata agaattcaac tgtgatggca agagcagaat atttcagaaa
2281 tgtagactat cttctcatcc acggaacagc agatgataat gtgcactttc aaaactcagc
2341 acagattgct aaagctctgg ttaatgcaca agtggatttc caggcaatgt ggtactctga
2401 ccagaaccac ggcttatccg gcctgtccac gaaccactta tacacccaca tgacccactt
2461 cctaaagcag tgtttctctt tgtcagacta aaaacgatgc agatgcaagc ctgtatcaga
2521 atctgaaaac cttatataaa cccctcagac agtttgctta ttttattttt tatgttgtaa
2581 aatgctagta taaacaaaca aattaatgtt gttctaaagg ctgttaaaaa aaagatgagg
2641 actcagaagt tcaagctaaa tattgtttac attttctggt actctgtgaa agaagagaaa
2701 agggagtcat gcattttgct ttggacacag tgttttatca cctgttcatt tgaagaaaaa
2761 taataaagtc agaagttc
//