LOCUS       HUMERK2A                1611 bp    mRNA    linear   HUM 31-DEC-1994
DEFINITION  Human extracellular signal-regulated kinase 2 mRNA, complete cds.
ACCESSION   M84489
VERSION     M84489.1
KEYWORDS    kinase 2.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1611)
  AUTHORS   Owaki,H., Makar,R., Boulton,T.G., Cobb,M.H. and Geppert,T.D.
  TITLE     Extracellular signal-regulated kinases in T cells: characterization
            of human ERK1 and ERK2 cDNAs
  JOURNAL   Biochem. Biophys. Res. Commun. 182 (3), 1416-1422 (1992)
   PUBMED   1540184
COMMENT     Original source text: Homo sapiens cDNA to mRNA.
FEATURES             Location/Qualifiers
     source          1..1611
                     /db_xref="H-InvDB:HIT000196579"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /cell_line="JURKAT"
                     /cell_type="T CELL"
     gene            1..1611
                     /gene="ERK2"
     CDS             328..1410
                     /gene="ERK2"
                     /codon_start=1
                     /product="protein kinase 2"
                     /protein_id="AAA58459.1"
                     /translation="MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYD
                     NVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVY
                     IVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTT
                     CDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL
                     AEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWN
                     RLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDME
                     LDDLPKEKLKELIFEETARFQPGYRS"
BASE COUNT          403 a          421 c          407 g          380 t
ORIGIN      
        1 acataatttc tggagccctg taccaacgtg tggccacata ttctgtcagg aaccctgtgt
       61 gatcatggtc tggatctgca acacgggcca ggccaaagtc acagatcttg agatcacagg
      121 tggtgttgag cagcaggcag gcaggcaatc ggtccgagtg gctgtcggct cttcagctct
      181 ccgctcggcg tcttccttcc tctcccggtc agcgtcggcg gctgcaccgg cggcgggcag
      241 tcctgcggga ggggcgacaa gagctgaggc gcggccgccg agcgtcgagc tcagcgcggc
      301 ggaggcggcg gcggcccggc agccaacatg gcggcggcgg cggcggcggg cgcgggcccg
      361 gagatggtcc gcgggcaggt gttcgacgtg gggccgcgct acaccaacct ctcgtacatc
      421 ggcgagggcg cctacggcat ggtgtgctct gcttatgata atgtcaacaa agttcgagta
      481 gctatcaaga aaatcagccc ctttgagcac cagacctact gccagagaac cctgagggag
      541 ataaaaatct tactgcgctt cagacatgag aacatcattg gaatcaatga cattattcga
      601 gcaccaacca tcgagcaaat gaaagatgta tatatagtac aggacctcat ggaaacagat
      661 ctttacaagc tcttgaagac acaacacctc agcaatgacc atatctgcta ttttctctac
      721 cagatcctca gagggttaaa atatatccat tcagctaacg ttctgcaccg tgacctcaag
      781 ccttccaacc tgctgctcaa caccacctgt gatctcaaga tctgtgactt tggcctggcc
      841 cgtgttgcag atccagacca tgatcacaca gggttcctga cagaatatgt ggccacacgt
      901 tggtacaggg ctccagaaat tatgttgaat tccaagggct acaccaagtc cattgatatt
      961 tggtctgtag gctgcattct ggcagaaatg ctttccaaca ggcccatctt tccagggaag
     1021 cattatcttg accagctgaa tcacattttg ggtattcttg gatccccatc acaagaagac
     1081 ctgaattgta taataaattt aaaagctagg aactatttgc tttctcttcc acacaaaaat
     1141 aaggtgccat ggaacaggct gttcccaaat gctgactcca aagctctgga cttattggac
     1201 aaaatgttga cattcaaccc acacaagagg attgaagtag aacaggctct ggcccaccca
     1261 tatctggagc agtattacga cccgagtgac gagcccatcg ccgaagcacc attcaagttc
     1321 gacatggaat tggatgactt gcctaaggaa aagctaaaag aactaatttt tgaagagact
     1381 gctagattcc agccaggata cagatcttaa atttgtcagg acaagggctc agaggactgg
     1441 acgtgctcag acatcggtgt tcttcttccc agttcttgac ccctggtcct gtctccagcc
     1501 cgtcttggct tatccacttt gactcctttg agccgtttgg aggggcggtt tctggtagtt
     1561 gtggctttta tgctttcaaa gaatttcttc agtccagaga attcactggc c
//