LOCUS HUMRIB 2366 bp mRNA linear HUM 10-NOV-1994
DEFINITION Human cAMP-dependent protein kinase regulatory subunit RI-beta
mRNA, 3' end.
ACCESSION M65066
VERSION M65066.1
KEYWORDS cAMP-dependent protein kinase RI-beta regulatory subunit.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2366)
AUTHORS Solberg,R., Tasken,K., Keiserud,A. and Jahnsen,T.
TITLE Molecular cloning, cDNA structure and tissue-specific expression of
the human regulatory subunit RI beta of cAMP-dependent protein
kinases
JOURNAL Biochem. Biophys. Res. Commun. 176 (1), 166-172 (1991)
PUBMED 1708242
REFERENCE 2 (bases 1 to 2366)
AUTHORS Solberg,R., Tasken,K., Wen,W., Coghlan,V.M., Meinkoth,J.L.,
Scott,J.D., Jahnsen,T. and Taylor,S.S.
TITLE Human regulatory subunit RI beta of cAMP-dependent protein kinases:
expression, holoenzyme formation and microinjection into living
cells
JOURNAL Exp. Cell Res. 214 (2), 595-605 (1994)
PUBMED 7925653
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2366
/db_xref="H-InvDB:HIT000196159"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="7p"
/tissue_type="testis"
/tissue_lib="Clontech HL 1010"
gene 1..2366
/gene="PRKAR1B"
CDS <1..1144
/gene="PRKAR1B"
/EC_number="2.7.11.1"
/codon_start=2
/product="cAMP-dependent protein kinase RI-beta regulatory
subunit"
/protein_id="AAC37564.1"
/translation="ASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPER
PMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPVVKARRRRGGVSAE
VYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAG
ETVIQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKT
DLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADRLEPVQFE
DGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPR
AATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV"
variation 844
/gene="PRKAR1B"
/note="t in clones 15 and 20, c in clone 36."
regulatory 1300..1305
/regulatory_class="polyA_signal_sequence"
/gene="PRKAR1B"
/note="potential; putative"
regulatory 2349..2354
/regulatory_class="polyA_signal_sequence"
/gene="PRKAR1B"
/note="potential; putative"
BASE COUNT 465 a 730 c 747 g 424 t
ORIGIN
1 ggcctccccg cccgcctgcc cctcggagga ggacgagagc ctgaagggct gtgagctgta
61 cgtgcagctg cacgggatcc agcaggtcct caaagactgt atcgtccacc tctgcatctc
121 caagcccgaa cgccccatga agttcctccg ggagcacttc gagaagctgg agaaggaaga
181 aaacaggcag attttggcgc ggcaaaagtc aaactcacag tcggactccc atgatgagga
241 ggtgtcgccc acccccccga accctgtggt gaaggcccgc cgccggcgag gaggcgtgag
301 tgccgaggtg tacaccgagg aggacgccgt gtcctacgtc aggaaggtga ttcccaagga
361 ctacaaaacc atgactgcgc tggccaaggc catctccaag aacgtgctct tcgctcacct
421 ggatgacaac gagaggagtg acatattcga tgccatgttc cctgtcactc acatcgctgg
481 ggagactgtt atacagcaag ggaatgaagg agacaacttc tatgtcgttg atcaagggga
541 agtggatgtg tacgtgaacg gagagtgggt gaccaacatc agcgagggag gcagcttcgg
601 ggagctggcg ctcatctacg gcacccccag ggctgcgacc gtgaaagcca agacggacct
661 caagctctgg gggatcgacc gggacagcta ccggcgcatc cttatgggca gcacgctgag
721 gaaacgcaag atgtacgagg agttcctcag caaggtctcc atcctagagt ccctggagaa
781 gtgggagcgt ctgaccgtgg cggatcggct ggagcccgtc cagtttgaag atggagagaa
841 aattgtggtc cagggagagc ctggggacga cttttacatc atcacggagg gcaccgcgtc
901 cgtgctgcag cgccggtccc ccaatgagga gtacgtggag gtggggcgcc tgggaccctc
961 tgactacttc ggggagattg cactgctgct gaaccggccc cgggcggcca ctgtcgtggc
1021 ccgggggccc ctcaagtgtg tgaagctgga ccggccccgc ttcgagcgtg tgctggggcc
1081 ctgctctgag atcctcaaga ggaacattca gcgttacaac agcttcatct ccctcaccgt
1141 ctgagcacac gtcccgccct gcagccccag ctccccagtg tggtggccgt gcctgctcgt
1201 ctgtgtcggg ggcccgggag ccgctgtgtg aggtgtgggc cgggtggggc tgggtcccgg
1261 cagcgtgagg actgcccctt ccccggactc actttttgga ataaatgatc accttgtgca
1321 tttccaaatc aaaggacaag cggacaaaat gcatcccaag atcaaggaag ggacaggcca
1381 gcttcctccc cacacgcctc cccggctgcc tctgtgggct tctcctgggg ggcccacccc
1441 acccctgcca gtctcctgga gatgcttgag gatcggtcct ccccagaacc aggccaggac
1501 gttgcccctg gcggctggtg accctgtgag gtcaggtccc ccagattgag gtctgagtgt
1561 gggcaagtgt gtcaaaaggg gctgcccccc aggagatgag gctgagagca gggagttgag
1621 gccgaagaag tcaaggcccc tcccgcaaat gtgtacccct gcccgcgcca ctgcaccccg
1681 ccgcaccccc acctccccgg gggccctgct gcggatcgcg gagtgggaga gtctctgagc
1741 tatgagattg atcttgcccc taattggaga ggaagccggg cgccaagaca cacggggctc
1801 ctgccttggg agccagggcc gcggccgcag gtagacccca gtaggggggg ccgggctcga
1861 agttcctttg ggaggggctg gcgggactcc agcaggccgt cctcaccttt cttagaaagt
1921 ccacccaggg caagttgatg ttgggggaaa gcagaagtca agccagccgc ggccccacac
1981 gccccgaccc gctcaaccga cttgtccctt aaatgtgtct tggatcccgc agtgatgacg
2041 tgagccagcc aggcccgaaa gggtgaggcc agtgcagaga agcttcccag gggattcctg
2101 gttcccccga aagacaagcg aggtcattgc agttcacccg atgttgctcc tgtcccgtgc
2161 gtcccgggga ggctgtcctt ggtccgcatg gctcgttgca gcccctcccc tgctggcggt
2221 tacgatgcgt ggggtccccc tccccaccca gccccggcac cgtcgccgtg tcccgcctgt
2281 gcctgtgacg tccctgtgga cctgtgagcc atccccccct tatctctgct ctgaatactg
2341 catgaagcat taaacgtgca atgaag
//