LOCUS HUMGMCSF 1480 bp mRNA linear HUM 27-APR-1993
DEFINITION Human GM-CSF receptor mRNA, complete cds.
ACCESSION M64445
VERSION M64445.1
KEYWORDS GM-CSF receptor; hematopoietin receptor; transmembrane protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1480)
AUTHORS Crosier,K.E., Wong,G.G., Mathey-Prevot,B., Nathan,D.G. and
Sieff,C.A.
TITLE A functional isoform of the human granulocyte/macrophage
colony-stimulating factor receptor has an unusual cytoplasmic
domain
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88 (17), 7744-7748 (1991)
PUBMED 1715577
COMMENT Original source text: Homo sapiens (library: cDNA) cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1480
/db_xref="H-InvDB:HIT000196130_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="M-07"
/tissue_lib="cDNA"
gene 1..1480
/gene="GM-CSF receptor"
CDS 163..1395
/gene="GM-CSF receptor"
/codon_start=1
/product="GM-CSF receptor"
/protein_id="AAA35908.1"
/translation="MLLLVTSLLLCELPHPAFLLIPEKSDLRTVAPASSLNVRFDSRT
MNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNTSQ
RGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRR
REIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIERF
NPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGD
LENRYNFPSSEPRAKHSVKIRAADVRILNWSSWSEAIEFGSDDGNLGSVYIYVLLIVG
TLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKLNDNHEVEDEMGPQRHHRCGWNLYPTP
GPSPGSGSSPRLGSESSL"
BASE COUNT 394 a 361 c 380 g 345 t
ORIGIN
1 ccgagagaag aaaagcaggt ggaaggagag gaagctgatg ccgtggggtt tacagcagga
61 aaatccgtgg agacagcaga tccgagaagc ggcgatgttt gcgtagaacc ctgtacgtgc
121 ttccttcggc ctgtcgctct tcccttctct ctgaccagca ccatgcttct cctggtgaca
181 agccttctgc tctgtgagtt accacaccca gcattcctcc tgatcccaga gaaatcggat
241 ctgcgaacag tggcaccagc ctctagtctc aatgtgaggt ttgactccag gacgatgaat
301 ttaagctggg actgccaaga aaacacaacc ttcagcaagt gtttcttaac tgacaagaag
361 aacagagtcg tggaacccag gctcagtaac aacgaatgtt cgtgcacatt tcgtgaaatt
421 tgtctgcatg aaggagtcac atttgaggtt cacgtgaata ctagtcaaag aggatttcaa
481 cagaaactgc tttatccaaa ttcaggaagg gagggtaccg ctgctcagaa tttctcctgt
541 ttcatctaca atgcggattt aatgaactgt acctgggcga ggggtccgac ggccccccgt
601 gacgtccagt attttttgta catacgaaac tcaaagagaa ggagggagat ccggtgtcct
661 tattacatac aagactcagg aacccatgtg ggatgtcacc tggataacct gtcaggatta
721 acgtctcgca attactttct ggttaacgga accagccgag aaattggcat ccaattcttt
781 gattcacttt tggacacaaa gaaaatagaa cgattcaacc ctcccagcaa tgtcaccgta
841 cgttgcaaca cgacgcactg cctcgtacgg tggaaacagc ccaggaccta tcagaagctg
901 tcgtacctgg actttcagta ccagctggac gtccacagaa agaataccca gcctggcacg
961 gaaaacctac tgattaatgt ttctggtgat ttggaaaata gatacaactt tccaagctct
1021 gagcccagag caaaacacag tgtgaagatc agagctgcag acgtccgcat cttgaattgg
1081 agctcctgga gtgaagccat tgaatttggt tctgacgacg ggaacctcgg ctctgtgtac
1141 atttatgtgc tcctaatcgt gggaaccctt gtctgtggca tcgtcctcgg cttcctcttt
1201 aaaaggttcc ttaggataca gcggctgttc ccgccagttc cacagatcaa agacaaactg
1261 aatgataacc atgaggtgga agacgagatg ggaccgcagc gtcaccaccg gtgtggctgg
1321 aatctgtatc ccactcctgg gccttctccc gggtcggggt cttctccaag gttggggtca
1381 gagtcatctc tgtgagctcc atcaggagaa actgaggcag ggtggtggtc aagaaaagga
1441 ggagaagacg gtagagaggg ccaggcacgg tggctcatct
//