LOCUS HUMVENHK1 2445 bp mRNA linear HUM 14-JAN-1995
DEFINITION Human voltage-gated potassium channel (HK1) mRNA, complete cds.
ACCESSION M60450
VERSION M60450.1
KEYWORDS voltage-gated potassium channel.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2445)
AUTHORS Tamkun,M.M., Knoth,K.M., Walbridge,J.A., Kroemer,H., Roden,D.M. and
Glover,D.M.
TITLE Molecular cloning and characterization of two voltage-gated K+
channel cDNAs from human ventricle
JOURNAL FASEB J. 5 (3), 331-337 (1991)
PUBMED 2001794
COMMENT Original source text: Homo sapiens ventricular cardiac muscle cDNA
to mRNA.
FEATURES Location/Qualifiers
source 1..2445
/db_xref="H-InvDB:HIT000195938"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="ventricular cardiac muscle"
gene 1..2445
/gene="HK1"
CDS 298..2259
/gene="HK1"
/standard_name="KCNA4"
/standard_name="Kv1.4"
/codon_start=1
/product="voltage-gated potassium channel"
/protein_id="AAA61275.1"
/db_xref="GDB:G00-120-044"
/translation="MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRAAAAAAV
AAATAAVEGSGGSGGGSHHHHQSRGACTSHDPQSSRGSRRRRRQRSEKKKAHYRQSSF
PHCSDLMPSGSEEKILRELSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQD
EGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNE
YFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFV
REEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRD
DRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFA
CPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVR
VFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHF
QSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF
YHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCA
KEEKCQGKGDDSETDKNNCSNAKAVETDV"
BASE COUNT 612 a 563 c 648 g 622 t
ORIGIN
1 aacataggtg tctgagagac tccagcattt tcggacttct tagtcttgag agtgccaggc
61 tatttatctc gaccagccaa gctctggaga gcaatgttga atccctgaga agagagagca
121 tggggcgtgc tgatttaaaa acagaaaatg caaagttgga ctgaaaatat ccttagtctt
181 ccaagcaatc tgcttaaggg ttccaaactt accttaattt ggtgagaaaa gaagctgccc
241 tatttttctt tcttcttctt ctacaactgg aaccagccat ttccgaaaac caccaccatg
301 gaggttgcaa tggtgagtgc ggagagctca gggtgcaaca gtcacatgcc ttatggttat
361 gctgcccagg cccgggcccg ggagcgggag aggcttgctc actccagggc agctgcagca
421 gctgctgttg cagcggccac agctgctgtc gaaggtagcg ggggttctgg tgggggctcc
481 caccaccacc accagtcacg cggggcctgt acctcccatg accctcagag cagccggggt
541 agtcggagga ggaggcgaca gcggtctgag aagaagaaag cccactaccg gcagagcagc
601 ttccctcatt gctctgacct gatgcccagt ggctctgagg agaagatcct gagggagctg
661 agtgaggagg aggaagatga ggaggaggag gaagaggagg aagaggaggg aaggttttac
721 tatagtgaag atgaccatgg tgatgagtgt tcctacacgg atctgctgcc tcaggatgag
781 ggcggtggcg gctacagttc agtccgctac agtgactgtt gtgaacgtgt ggtgataaat
841 gtgtcaggcc tacgctttga gacccaaatg aaaactctgg cccagtttcc agagactttg
901 ttgggagacc ctgaaaagag gactcagtac tttgaccctt tgcgcaatga gtattttttt
961 gacaggaacc gccccagctt tgatgccatc ttgtattatt atcaatcagg aggccgcctg
1021 aagaggccag tcaatgtccc ctttgatatc ttcactgagg aggtgaagtt ctatcagttg
1081 ggggaggagg ccctgttgaa gtttcgggag gacgagggct ttgtgagaga agaggaagac
1141 agggccctcc ccgagaatga atttaaaaag cagatttggc tcctctttga atatccagag
1201 agctccagtc ctgcaagggg catagccatt gtgtccgtcc tggtcatctt aatctccatt
1261 gtcatctttt gcctggaaac cttgcctgag tttagggacg acagggatct cgtcatggca
1321 ctgagtgctg gcgggcatgg tgggttgttg aatgatactt cagcacccca tctggagaac
1381 tcagggcaca caatattcaa tgaccccttc ttcatcgtgg aaacagtctg tattgtatgg
1441 ttttcctttg agtttgtggt tcgctgcttt gcttgtccca gccaagcact cttcttcaaa
1501 aacatcatga acatcattga cattgtctcc attttgcctt acttcatcac actgggcact
1561 gacctggccc agcaacaggg gggtggcaat ggtcagcagc agcaggccat gtcctttgcc
1621 atcctcagaa tcattcgtct ggtccgagta ttccggatct tcaaactctc caggcactcc
1681 aaaggcctgc agatcctggg ccacaccctc agagccagca tgcgggaact gggccttctg
1741 atcttcttcc tcttcattgg ggtcatcctc ttttctagtg ctgtgtattt tgcagaggcg
1801 gatgaaccta ctacccattt ccaaagcatc ccagatgcat tttggtgggc tgtggtgacc
1861 atgacaactg tgggctatgg ggacatgaag cccatcactg tagggggcaa gattgtcggg
1921 tccctgtgtg ccattgcggg tgtcttaacc attgctttgc cagtgccagt gattgtctct
1981 aactttaact atttctacca cagagagact gaaaatgagg aacagacaca gctaacgcag
2041 aatgcagtca gttgtccata cctcccctct aatttgctca agaaatttcg gagctctact
2101 tcttcttccc tgggggacaa gtcagagtat ctagagatgg aagaaggagt taaggaatct
2161 ctgtgtgcaa aggaggagaa gtgtcaggga aagggggatg acagtgagac agataaaaac
2221 aactgttcta atgcaaaggc tgtggagact gatgtgtgaa tctttttcca cctgccactg
2281 ctcccccctc agcatctcca aatatattta tgcatagaga gtgcagttat gaaaatgaaa
2341 tatgcaaatg atccaatgca tacagtagta cactatttaa tggttataca tggcataatt
2401 gttactaaac ttgtattaca tatcaaataa atgatacatc ttgga
//