LOCUS HUMBMYH7CD 6008 bp mRNA linear HUM 06-MAR-1995
DEFINITION Homo sapiens beta-myosin heavy chain (MYH7) mRNA, complete cds.
ACCESSION M58018
VERSION M58018.1
KEYWORDS beta-myosin heavy chain; cardiac myosin heavy chain.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6008)
AUTHORS Jaenicke,T., Diederich,K.W., Haas,W., Schleich,J., Lichter,P.,
Pfordt,M., Bach,A. and Vosberg,H.P.
TITLE The complete sequence of the human beta-myosin heavy chain gene and
a comparative analysis of its product
JOURNAL Genomics 8 (2), 194-206 (1990)
PUBMED 2249844
COMMENT Original source text: Human leukocyte, cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..6008
/db_xref="H-InvDB:HIT000195856"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="14q11.2-q13"
/clone="lambda gMHC-1"
/clone="lambda gMHC-2"
/clone="lambda gMHC-3"
/clone="lambda gMHC-4"
/cell_type="leukocyte"
/tissue_type="blood"
/dev_stage="adult"
gene 1..6008
/gene="MYH7"
CDS 87..5894
/gene="MYH7"
/codon_start=1
/product="beta-myosin heavy chain"
/protein_id="AAA62830.1"
/db_xref="GDB:G00-120-215"
/translation="MGDSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQ
EFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVL
YNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDN
AYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLED
QIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQ
LKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDN
AFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNS
ADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETK
QPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW
TFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP
RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY
AGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPG
VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRK
GAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLAR
MEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEF
TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQ
LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE
NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQ
VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN
ALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEI
SERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG
EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSK
AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLE
EEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD
AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN
AAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH
LETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLE
HEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNE
ALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK
ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ
KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK
NMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRK
SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ
HELDEAEERADIAESQVNKLRAKSRDIGTKGLNEE"
BASE COUNT 1612 a 1560 c 1877 g 959 t
ORIGIN 14q.
1 tgtctttccc tgctgctctc aggtcccctg caggccttgg cccctttcct catctgtaga
61 cacacttgag tagcccaggc acagccatgg gagattcgga gatggcagtc tttggggctg
121 ccgcccccta cctgcgcaag tcagagaagg agcggctaga agcgcagacc aggccttttg
181 acctcaagaa ggatgtcttc gtgcctgatg acaaacagga gtttgtcaag gccaagatcg
241 tgtctcgaga gggtggcaaa gtcactgccg agactgagta tggcaagaca gtgaccgtga
301 aggaggacca ggtgatgcag cagaacccac ccaagttcga caaaatcgag gacatggcca
361 tgctgacctt cctgcatgag cccgcggtgc tctacaacct caaggatcgc tacggctcct
421 ggatgatcta cacctactcg ggcctcttct gtgtcaccgt caacccttac aagtggctgc
481 cggtgtacac tcctgaggtg gtggctgcct accggggcaa gaagaggagc gaggccccgc
541 cccacatctt ctccatctcc gacaacgcct atcagtacat gctgacagac agagaaaacc
601 agtccatcct gatcaccgga gaatccggag cagggaagac agtcaacacc aagagggtca
661 tccagtactt tgctgttatt gcagccattg gggaccgcag caagaaggac cagagcccgg
721 gcaagggcac cctggaggac cagatcatcc aggccaaccc tgctctggag gcctttggca
781 atgccaagac cgtccggaac gacaactcct cccgcttcgg gaaattcatt cgaattcatt
841 ttggggcaac aggaaagttg gcatctgcag acatagagac ctatcttctg gaaaaatcca
901 gagttatttt ccagctgaaa gcagagagag attatcacat tttctaccaa atcctgtcta
961 acaaaaagcc tgagctgctg gacatgctgc tgatcaccaa caacccctac gattatgcat
1021 tcatctccca aggagagacc accgtggcct ccattgatga cgctgaggag ctcatggcca
1081 ctgataacgc ttttgatgtg ctgggcttca cttcagagga gaaaaactcc atgtataagc
1141 tgacaggcgc catcatgcac tttggaaaca tgaagttcaa gctgaagcag cgggaggagc
1201 aggcggagcc agacggcact gaagaggctg acaagtctgc ctacctcatg gggctgaact
1261 cagccgacct gctcaagggg ctgtgccacc ctcgggtgaa agtgggcaat gagtacgtca
1321 ccaaggggca gaatgtccag caggtgatat atgccactgg ggcactggcc aaggcagtgt
1381 atgagaggat gttcaactgg atggtgacgc gcatcaatgc caccctggag accaagcagc
1441 cacgccagta cttcatagga gtcctggaca tcgctggctt cgagatcttc gatttcaaca
1501 gctttgagca gctctgcatc aacttcacca acgagaagct gcagcagttc ttcaaccacc
1561 acatgtttgt gctggagcag gaggagtaca agaaggaggg catcgagtgg acattcattg
1621 actttggcat ggacctgcag gcctgcattg acctcatcga gaagcccatg ggcatcatgt
1681 ccatcctgga agaggagtgc atgttcccca aggccaccga catgaccttc aaggccaagc
1741 tgtttgacaa ccacctgggc aaatccgcca acttccagaa gccacgaaat atcaagggga
1801 agcctgaagc ccacttctcc ctgatccact atgccggcat cgtggactac aacatcattg
1861 gctggctgca gaagaacaag gatcctctca atgagactgt cgtgggcttg tatcagaagt
1921 cttccctcaa gttgctcagc accctgtttg ccaactatgc tggggctgat gcgcctattg
1981 agaagggcaa aggcaaggcc aagaaaggct cgtcctttca gactgtgtca gctctgcaca
2041 gggaaaatct gaacaagctg atgaccaact tgcgctccac ccatccccac tttgtacgtt
2101 gtatcatccc taatgagaca aagtctccag gcgtgatgga caaccccctg gtcatgcacc
2161 agctgcgctg caatggtgtg ctggagggca tccgcatctg caggaaaggc ttccccaacc
2221 gcatcctcta cggggacttc cggcagaggt atcgcatcct gaacccagcg gccatccctg
2281 agggacagtt cattgatagc aggaaggggg cagagaagct gctcagctcc ctggacattg
2341 atcacaacca gtacaagttt ggccacacca aggtgttctt caaggccggg ctgctggggc
2401 tgctggagga aatgagggac gagaggctga gccgcatcat cacgcgtatc caggcccagt
2461 cccgaggtgt gctcgccaga atggagtaca aaaagctgct ggaacgtaga gactccctgc
2521 tggtaatcca gtggaacatt cgggccttca tgggggtcaa gaattggccc tggatgaagc
2581 tctacttcaa gatcaagccg ctgctgaaga gtgcagaaag agagaaggag atggcctcca
2641 tgaaggagga gttcacacgc ctcaaagagg cgctagagaa gtccgaggct cgccgcaagg
2701 agctggagga gaagatggtg tccctgctgc aggagaagaa tgacctgcag ctccaagtgc
2761 aggcggaaca agacaacctg gcagatgctg aggagcgctg tgatcagctg atcaaaaaca
2821 agattcagct ggaggctaag gtgaaggaga tgaacgagag gctggaggat gaggaggaga
2881 tgaatgctga gctcactgcc aagaagcgca agttggaaga tgagtgctca gagctcaaaa
2941 gggacatcga tgatctggag ctgacactgg ccaaagtgga gaaggagaaa cacgcaacag
3001 agaacaaggt gaaaaacctg acagaggaga tggctgggct ggatgagatc attgccaagc
3061 tgaccaagga gaagaaagct ctgcaagagg cccaccaaca ggctctggat gaccttcagg
3121 ccgaggagga caaggtcaac accctgacta aggccaaagt caagctggag cagcaagtgg
3181 atgatctgga aggatccctg gagcaagaga agaaggtgcg catggacctg gagcgagcga
3241 agcggaagct ggagggcgac ctgaagctga cccaggagag catcatggac ctggagaatg
3301 acaagcagca gctggatgag cggctgaaaa aaaaagactt tgagctgaat gctctcaacg
3361 caaggattga ggatgaacag gccctcggca gccagctgca gaagaagctc aaggagcttc
3421 aggcacgcat cgaggagctg gaggaggagc tggagtccga gcgcaccgcc agggctaagg
3481 tggagaagct gcgctcagac ctgtctcggg agctggagga gatcagcgag cggctggaag
3541 aggccggcgg ggccacgtcc gtgcagatcg agatgaacaa gaagcgcgag gccgagttcc
3601 agaagatgcg gcgggacctg gaggaggcca cgctgcagca cgaggccact gccgcggccc
3661 tgcgcaagaa gcacgccgac agcgtggccg agctgggcga gcagatcgac aacctgcagc
3721 gggtgaagca gaagctggag aaggagaaga gcgagttcaa gctggagctg gatgacgtca
3781 cctccaacat ggagcagatc atcaaggcca aggctaacct ggagaagatg tgccggacct
3841 tggaagacca gatgaatgag caccggagca aggcggagga gacccagcgt tctgtcaacg
3901 acctcaccag ccagcgggcc aagttgcaaa ccgagaatgg tgagctgtcc cggcagctgg
3961 atgagaagga ggcactgatc tcccagctga cccgaggcaa gctcacctac acccagcagc
4021 tggaggacct caagaggcag ctggaggagg aggttaaggc gaagaacgcc ctggcccacg
4081 cactgcagtc ggcccggcat gactgcgacc tgctgcggga gcagtacgag gaggagacgg
4141 aggccaaggc cgagctgcag cgcgtccttt ccaaggccaa ctcggaggtg gcccagtgga
4201 ggaccaagta tgagacggac gccattcagc ggactgagga gctcgaggag gccaagaaga
4261 agctggccca gcggctgcag gaagctgagg aggccgtgga ggctgttaat gccaagtgct
4321 cctcgctgga gaagaccaag caccggctac agaatgagat cgaggacttg atggtggacg
4381 tagagcgctc caatgctgct gctgcagccc tggacaagaa gcagaggaac ttcgacaaga
4441 tcctggccga gtggaagcag aagtatgagg agtcgcagtc ggagctggag tcctcgcaga
4501 aggaggctcg ctccctcagc acagagctct tcaaactcaa gaacgcctat gaggagtccc
4561 tggaacatct ggagaccttc aagcgggaga acaaaaacct gcaggaggag atctccgact
4621 tgactgagca gttgggttcc agcggaaaga ctatccatga gctggagaag gtccgaaagc
4681 agctggaggc cgagaagatg gagctgcagt cagccctgga ggaggccgag gcctccctgg
4741 agcacgagga gggcaagatc ctccgggccc agctggagtt caaccagatc aaggcagaga
4801 tcgagcggaa gctggcagag aaggacgagg agatggaaca ggccaagcgc aaccacctgc
4861 gggtggtgga ctcgctgcag acctccctgg acgcagagac acgcagccgc aacgaggccc
4921 tgagggtgaa gaagaagatg gaaggagacc tcaatgagat ggagatccag ctcagccacg
4981 ccaaccgcat ggccgccgag gcccagaagc aagtcaagag cctccagagc ttgttgaagg
5041 acacccagat tcagctggac gatgcagtcc gtgccaacga cgacctgaag gagaacatcg
5101 ccatcgtgga gcggcgcaac aacctgctgc aggctgagct ggaggagttg cgtgccgtgg
5161 tggagcagac agagcggtcc cggaagctgg cggagcagga gctgattgag actagtgagc
5221 gggtgcagct gctgcattcc cagaacacca gcctcatcaa ccagaagaag aagatggatg
5281 ctgacctgtc ccagctccag actgaagtgg aggaggcagt gcaggagtgc aggaatgctg
5341 aggagaaggc caagaaggcc atcacggatg ccgccatgat ggcagaggag ctgaagaagg
5401 agcaggacac cagcgcccac ctggagcgca tgaagaagaa catggaacag accattaagg
5461 acctgcagca ccggctggac gaagccgagc agatcgccct caagggcggc aagaagcagc
5521 tgcagaagct ggaagcgcgg gtgcgggagc tggagaatga gctggaggcc gagcagaagc
5581 gcaacgcaga gtcggtgaag ggcatgagga agagcgagcg gcgcatcaag gagctcacct
5641 accagacgga ggaggacagg aaaaacctgc tgcggctgca ggacctggta gacaagctgc
5701 agctaaaggt caaggcctac aagcgccagg ccgaggaggc ggaggagcaa gccaacacca
5761 acctgtccaa gttccgcaag gtgcagcacg agctggatga ggcagaggag cgggcggaca
5821 tcgccgagtc ccaggtcaac aagctgcggg ccaagagccg tgacattggc acgaagggct
5881 tgaatgagga gtagctttgc cacatcttga tctgctcagc cctggaggtg ccagcaaagc
5941 cccatgctgg agcctgtgta acagctcctt gggaggaagc agaataaagc aattttcctt
6001 gaagccga
//