LOCUS HUMHUGBR1 2351 bp mRNA linear HUM 07-MAR-1995
DEFINITION Human bilirubin UDP-glucuronosyltransferase isozyme 1 mRNA,
complete cds.
ACCESSION M57899
VERSION M57899.1
KEYWORDS UDP-glucuronosyltransferase; bilirubin UDP-glucuronosyltransferase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2351)
AUTHORS Ritter,J.K., Crawford,J.M. and Owens,I.S.
TITLE Cloning of two human liver bilirubin UDP-glucuronosyltransferase
cDNAs with expression in COS-1 cells
JOURNAL J. Biol. Chem. 266 (2), 1043-1047 (1991)
PUBMED 1898728
COMMENT Original source text: Human adult female liver, cDNA to mRNA,
clones Z6, Z11 and Z6MB2.
FEATURES Location/Qualifiers
source 1..2351
/db_xref="H-InvDB:HIT000195845"
/organism="Homo sapiens"
/mol_type="mRNA"
/isolate="AK"
/db_xref="taxon:9606"
/map="2"
/clone="Z6"
/sex="female"
/tissue_type="liver"
/dev_stage="adult"
/tissue_lib="lambda-ZAP"
gene 1..2351
/gene="UGT1"
CDS 16..1617
/gene="UGT1"
/EC_number="2.4.1.17"
/standard_name="bilirubin UDP-glucuronosyltransferase
isozyme 1"
/codon_start=1
/product="UDP-glucuronosyltransferase 1"
/protein_id="AAA63195.1"
/db_xref="GDB:G00-120-007"
/translation="MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSML
GAIQQLQQRGHEIVVLAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFEN
DSFLQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIV
AQYLSLPTVFFLHALPCSLEFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFS
QNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVG
GINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVL
WRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMP
LFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDR
PVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFK
CCAYGYRKCLGKKGRVKKAHKSKTH"
sig_peptide 43..75
/gene="UGT1"
/note="G00-120-007"
mat_peptide 76..1614
/gene="UGT1"
/product="UDP-glucuronosyltransferase 1"
/EC_number="2.4.1.17"
/standard_name="bilirubin UDP-glucuronosyltransferase
isozyme 1"
/note="G00-120-007"
BASE COUNT 601 a 540 c 557 g 653 t
ORIGIN
1 aggagcaaag gcgccatggc tgtggagtcc cagggcggac gcccacttgt cctgggcctg
61 ctgctgtgtg tgctgggccc agtggtgtcc catgctggga agatactgtt gatcccagtg
121 gatggcagcc actggctgag catgcttggg gccatccagc agctgcagca gaggggacat
181 gaaatagttg tcctagcacc tgacgcctcg ttgtacatca gagacggagc attttacacc
241 ttgaagacgt accctgtgcc attccaaagg gaggatgtga aagagtcttt tgttagtctc
301 gggcataatg tttttgagaa tgattctttc ctgcagcgtg tgatcaaaac atacaagaaa
361 ataaaaaagg actctgctat gcttttgtct ggctgttccc acttactgca caacaaggag
421 ctcatggcct ccctggcaga aagcagcttt gatgtcatgc tgacggaccc tttccttcct
481 tgcagcccca tcgtggccca gtacctgtct ctgcccactg tattcttctt gcatgcactg
541 ccatgcagcc tggaatttga ggctacccag tgccccaacc cattctccta cgtgcccagg
601 cctctctcct ctcattcaga tcacatgacc ttcctgcagc gggtgaagaa catgctcatt
661 gccttttcac agaactttct gtgcgacgtg gtttattccc cgtatgcaac ccttgcctca
721 gaattccttc agagagaggt gactgtccag gacctattga gctctgcatc tgtctggctg
781 tttagaagtg actttgtgaa ggattaccct aggcccatca tgcccaatat ggtttttgtt
841 ggtggaatca actgccttca ccaaaatcca ctatcccagg aatttgaagc ctacattaat
901 gcttctggag aacatggaat tgtggttttc tctttgggat caatggtctc agaaattcca
961 gagaagaaag ctatggcaat tgctgatgct ttgggcaaaa tccctcagac agtcctgtgg
1021 cggtacactg gaacccgacc atcgaatctt gcgaacaaca cgatacttgt taagtggcta
1081 ccccaaaacg atctgcttgg tcacccgatg acccgtgcct ttatcaccca tgctggttcc
1141 catggtgttt atgaaagcat atgcaatggc gttcccatgg tgatgatgcc cttgtttggt
1201 gatcagatgg acaatgcaaa gcgcatggag actaagggag ctggagtgac cctgaatgtt
1261 ctggaaatga cttctgaaga tttagaaaat gctctaaaag cagtcatcaa tgacaaaagt
1321 tacaaggaga acatcatgcg cctctccagc cttcacaagg accgcccggt ggagccgctg
1381 gacctggccg tgttctgggt ggagtttgtg atgaggcaca agggcgcgcc acacctgcgc
1441 cccgcagccc acgacctcac ctggtaccag taccattcct tggacgtgat tggtttcctc
1501 ttggccgtcg tgctgacagt ggccttcatc acctttaaat gttgtgctta tggctaccgg
1561 aaatgcttgg ggaaaaaagg gcgagttaag aaagcccaca aatccaagac ccattgagaa
1621 gtgggtggga aataaggtaa aattttgaac cattccctag tcatttccaa acttgaaaac
1681 agaatcagtg ttaaattcat tttattctta ttaaggaaat actttgcata aattaatcag
1741 ccccagagtg ctttaaaaaa ttctcttaaa taaaaataat agactcgcta gtcagtaaag
1801 atatttgaat atgtatcgtg ccccctccgg tgtctttgat caggatgaca tgtgccattt
1861 ttcagaggac gtgcagacag gctggcattc tagattactt ttcttactct gaaacatggc
1921 ctgtttggga gtgcgggatt caaaggtggt cccaccgctg cccctactgc aaatggcagt
1981 tttaatctta tcttttggct tctgcagatg gttgcaattg atccttaacc aataatggtc
2041 agtcctcatc tctgtcctgc ttcataggtg ccaccttgtg tgtttaaaga agggaagctt
2101 tgtaccttta gagtgtaggt gaaatgaatg aatggcttgg agtgcactga gaacagcata
2161 tgatttcttg ctttggggaa aaagaatgat gctatgaaat tggtgggtgg tgtatttgag
2221 aagataatca ttgcttatgt caaatggagc tgaatttgat aaaaacccaa aatacagcta
2281 tgaagtgctg ggcaagttta ctttttttct gatgtttcct acaactaaaa ataaattaat
2341 aaatttataa a
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