LOCUS HUMPROZII 1551 bp mRNA linear HUM 27-APR-1993
DEFINITION Human protein Z (plus 66 bp insertion) mRNA, complete cds.
ACCESSION M55671
VERSION M55671.1
KEYWORDS plasma glycoprotein; protein Z.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1551)
AUTHORS Ichinose,A., Takeya,H., Espling,E., Iwanaga,S., Kisiel,W. and
Davie,E.W.
TITLE Amino acid sequence of human protein Z, a vitamin K-dependent
plasma glycoprotein
JOURNAL Biochem. Biophys. Res. Commun. 172 (3), 1139-1144 (1990)
PUBMED 2244898
COMMENT Original source text: Human liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1551
/db_xref="H-InvDB:HIT000195810"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="Hep G-2"
/tissue_type="liver"
gene 1..1551
/gene="human protein Z"
mRNA <1..1551
/gene="human protein Z"
CDS 8..1276
/gene="human protein Z"
/codon_start=1
/product="protein Z"
/protein_id="AAA36501.1"
/translation="MAGCVPLLQGLVLVLALHRVEPSATSLKERHGLHSDSACTGVQE
SLFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDE
FWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQ
HFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRAPDLQDLPWQVKLTN
SEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYD
ADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGN
SLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSWFLTGV
LGSQPVGGQAHMVLVTKVSRYSLWFKQIMN"
sig_peptide 8..76
/gene="human protein Z"
mat_peptide 194..1273
/gene="human protein Z"
/product="protein Z"
BASE COUNT 390 a 419 c 426 g 316 t
ORIGIN
1 ggtgggaatg gcaggctgcg tcccactgct ccagggcctg gtcctggtcc tcgccctcca
61 tcgtgtggag ccctcagcca cttcactgaa ggaacgacat ggactccatt ctgactctgc
121 ctgcacaggc gtccaggaaa gcttatttct cccggcctcc aaagcaaacg acgttctggt
181 gaggtggaag cgtgcgggct cctatcttct ggaagaactc ttcgagggaa acttggaaaa
241 agaatgttat gaagaaatct gtgtctatga agaagcaaga gaagtgtttg aaaatgaagt
301 agtcactgat gaattctgga gacgatataa gggcggctcc ccgtgcatct cccagccctg
361 cctccacaac ggctcttgcc aggacagcat ctggggctac acctgcacct gctcccccgg
421 ctatgagggc agcaactgcg agctggctaa aaatgaatgt cacccagagc ggactgatgg
481 gtgtcaacac ttctgcctcc caggacagga atcctacacg tgcagctgtg ctcagggcta
541 caggcttggt gaggaccaca aacagtgtgt gccccacgac cagtgtgcct gcggggtgct
601 gacctctgag aagcgtgcac cggatctaca ggacctcccg tggcaggtaa agttaacaaa
661 ttccgaagga aaagacttct gtggtggtgt tataatacgg gaaaattttg tactgacaac
721 agcaaaatgt tcactgttac acaggaatat tactgtaaaa acatatttta acagaacgag
781 ccaagacccg ctgatgatca agataacgca cgtccatgtg cacatgcggt atgacgcgga
841 cgcgggggag aatgacctgt cactgctgga gctggagtgg cccatccagt gcccaggtgc
901 ggggctcccc gtgtgcaccc ctgagaaaga cttcgctgag cacctcctca tcccacgcac
961 caggggcctc ctcagcggct gggcacgcaa tggcactgac ctgggcaact cgctgaccac
1021 gcggcctgtc acacttgtgg agggggagga gtgcgggcag gtcctgaatg tgactgtcac
1081 caccaggacc tactgtgaga gaagcagcgt ggcggccatg cactggatgg atggaagtgt
1141 ggtcaccaga gaacacagag gctcctggtt tctcacgggg gtcctgggct cgcagccagt
1201 aggagggcag gctcacatgg tccttgtcac caaggtctcc aggtactcac tctggtttaa
1261 acagatcatg aactaactga aactcagcta gccagaatga acaacacaac cggaagcggg
1321 attccaagct ggcactgcca ctgtggaggg cgctgaaact tcatcacaca ctgagaggcc
1381 gtcacagccc cagaccaccc gcttggccca cgcagcagca gagccgccgt ttgctgggtt
1441 gtttaccgag cactgtgacc tttctttccc tggaactctt tatctcaata gagaccttaa
1501 aagaaaacat gagatacgtt aaataataaa ataagataat ctgtcagtca t
//